Navigation Links
Swelling of Prostate Gland Prevented with New drug

Estrogen regulating drugs might aid in prevention of enlargement of the prostate gland in older men according to Australian scientists. //

Results of animal studies that were presented at a medical conference in London showed that an experimental estrogen-regulating drug prevented the swelling of the prostate gland which occurs as men age.

Professor Gail Risbridger, of Monash University in Melbourne said, “We still have to try the drugs in humans, but so far these are very promising results.”

“This work holds out the possibility that we may be able to help patients with benign disease as well as men with prostate cancer by using these designer drugs.”

Enlarged prostate, or benign prostate hyperplasia (BPH) is a common disease in men over 60 causing urinary problems, infections and pain.

Although estrogen is generally considered a female hormone it also plays a role in the development of the prostate gland having both positive and negative effects.

Risbridger said, “There are two things that estrogens do, good and bad, but in different diseases.”

The bad effect is that the hormone can cause malignancy but on the positive side it can stop BPH from developing.

On testing an estrogen receptor-beta agonist on transgenic mice with BPH Risbridger and her team found that the drug activated just one of the two cell receptors for the hormone to produce the positive impact. This was presented at the Society for Endocrinology conference.

The scientists found that regulating the estrogen receptor beta stopped the development of benign prostate hyperplasia, while the negative effects were due to switching on the estrogen receptor alpha.

She said, “When you give one of the estrogen selective drugs that only activates a particular type of estrogen receptor, beta, you can prevent the hyperplasia from developing.”

The drug was found to stop the development of the illness and improve the health of the animals which had existing BPH.

Risbridger added, “Ideally, we would want to promote the good effects of estrogen receptor beta and block the bad effects of estrogen receptor alpha.”

“It’s interesting work, and we are pleased that preclinical testing may translate into real benefits for patients.”


Related medicine news :

1. Swelling increases stroke risk with high B.P.
2. Do Not Neglect Your Abdominal Pain/ Swelling - Help Your Doctor In Early Cancer Detection
3. Brain Swelling Key to Reducing Stroke Fatalities
4. Surgeon Develops Procedure to Prevent Arm Swelling in Breast Cancer Patients
5. Cancer Doctors Okays Controversial Prostate Therapy
6. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
7. New Prostate Cancer Vaccine Shows Promise
8. Hormone Therapy applicable for Prostate Cancer
9. Prostate cancer and Vitamins
10. Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time
11. Early Detection Of Prostate Cancer
Post Your Comments:

(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
(Date:10/12/2017)... Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... is holding a treadmill relay – Miles by Moonlight to raise money for the ... donating $300 or more. , Teams will work together to keep their treadmills ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  BioPharmX Corporation (NYSE ... team that developed an innovative way to use nonlinear ... the delivery of new drugs. ... Clinical Dermatology Conference will show how researchers from BioPharmX ... Harvard Medical School used a suite of imaging techniques ...
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
Breaking Medicine Technology: