Navigation Links
Susceptibility Of TB In Humans Might Be Due To Three Human Gene Variants

A new study has reported that there appears to be three variations of a human gene that seem to cause an impact on humans upon their susceptibility towards tuberculosis// . Researchers hope that these findings would provide sufficient knowledge as to why some patients infected with the Mycobacterium tuberculosis pathogen develop the full-blown disease while others are seemingly not affected. The findings was published in the online edition of the Proceedings of the National Academy of Sciences (PNAS) (http://www.pnas.org/) for the week of June 19-23,

The paper additionally describes how the association of two of the gene variants with the disease has been replicated.

Approximately one-third of the world's population is thought to be infected with the M. tuberculosis pathogen, yet only about 10 percent becomes ill with the active disease. Researchers suspect that a variety of factors interplay to determine who develops the full-blown disease. For example, in February 2006 Harvard School of Public Health (HSPH) researchers were part of a team that identified a mechanism that explains why people of African descent may be more vulnerable to the disease.
(http://www.hsph.harvard.edu/press/
releases/press02232006B.html)

Now HSPH Associate Professor Igor Kramnik is part of a team led by Professor Adrian V.S. Hill of Oxford University that has identified three variations of a human gene associated with tuberculosis susceptibility. The lead author on the paper is Kerrie Tosh of the Welcome Trust Centre for Human Genetics in the U.K.

Kramnik and his colleagues had previously identified a gene in mice called Ipr1 (intracellular pathogen resistance 1) that plays a significant role in limiting the multiplication of intracellular pathogens M. tuberculosis and Listeria monocytogenes inside host cells.
(http://www.hsph.harvard.edu/press/
releases/press04062005.html)

The Hill team then examined the closest ho
'"/>




Page: 1 2

Related medicine news :

1. Popularity Among Peers Increases Susceptibility To Smoking Habit Among School Children
2. Smoking Related Scenes in Movies Increase Teenage Susceptibility To Smoke
3. A Sneak Preview of Human’s Susceptibility to Auto Immune Disease, Allergy, Asthm
4. Gene Defects Determine Susceptibility to Cancer and Bone Marrow Failure
5. Gluten Intolerance Quadruples Susceptibility to Tuberculosis
6. Web-Based Genomics Tool Designed to Help Predict Disease Susceptibility
7. Susceptibility to TB is High Among the Smokers
8. First Vaccine Designed for Africa Cleared for Testing in Humans
9. Humans Found To Have The Ability To Block Unwanted Memories
10. US Senate Votes against Testing of Pesticide on Humans
11. Limb Regeneration In Humans: A Future Possibility
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Susceptibility Humans Might Due Three Human Gene Variants

(Date:7/12/2014)... my mom’s stroke, she loss the use of her right side. ... his left side. Eating became a difficult task for them so ... enjoy eating again,” said an inventor, from Fayetteville, N.C. As a ... (P C H PLATE). , The PATRICIA CAROL HALL PLATE (P ... individuals who suffer from stroke, experience tremors or loss of movement. ...
(Date:7/12/2014)... New York (PRWEB) July 12, 2014 ... to move forward in U.S. courts, Bernstein Liebhard LLP ... elevated metal ion levels to the failure of metal-on-metal ... 2nd issue of The Journal of Bone & Joint ... received unilateral Articular Surface Replacement prostheses at least twelve ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 For those who ... bodies can readily absorb the nutrients in food. The enzymes ... that are small enough to be absorbed by human bodies. ... a lack of enzymes in regular food is the cause ... product that was started by Michelle DelPresto, a mother of ...
(Date:7/12/2014)... 2014 “Critical Care Therapeutics in ... Late-Stage Four-Factor PCCs and Recombinant Products to Drive ... care market in the US, UK, France, Germany, ... an estimation of market size for 2013, along ... care indications that are being treated using the ...
(Date:7/12/2014)... 2014 As reported in this July ... and Technology), the June 25th, 2014 Supreme Court ruling in ... world. It was also met with both cheers and ... it was seen from an individual privacy perspective, or a ... there is now precedent which will require law enforcement officials ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 2Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 3Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 4Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 3Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 5Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 6Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5
... during college, survey shows , , MONDAY, July 7 (HealthDay ... common before and during college, a new study shows. ... (57.1 percent female) at three urban college campuses to ... , 407 (44.7 percent) of respondents said they experienced ...
... the risk seems bigger if certain painkillers are ... News) -- The widely prescribed class of antidepressants ... in the upper gastrointestinal tract, especially when taken ... study says. , Although reports of this effect ...
... Preserve Vital Stem Cells During, Their Menstrual Flow; Potential for Future Anti-Aging ... ... Fla., July 7 With today,s hectic,lifestyle, where most women are juggling ... a serious illness in,the future is not something that readily comes to ...
... HARRISBURG, Pa., July 7 Need to find ... area? Are you,a senior citizen living in Pennsylvania ... information on oral health topics such as,brushing and ... no,further! PDA,s website, http://www.padental.org, is an ...
... CCA Industries,Inc. (Amex: CAW ) declared today a ... shareholders of record as of August 1, 2008, payable on,September ... 31, 2008 were $17,389,985.,Net income was $790,692 and earnings per ... of $1,292,921 and earnings per,share of $0.18 fully diluted for ...
... In a New York City metro-area first, a 93-year-old ... at NewYork-Presbyterian Hospital, the only center on the Eastern ... new stent graft was implanted under an FDA-approved clinical ... a complex form of abdominal aortic aneurysms in which ...
Cached Medicine News:Health News:Relationship Violence Common Among College Students 2Health News:Popular Antidepressants Linked to GI Bleeding 2Health News:Popular Antidepressants Linked to GI Bleeding 3Health News:Taking Control: Future Therapies for a Host of Serious Diseases May Be Found in Women's Menstrual Blood 2Health News:Pennsylvania Dental Association Website: A Great Resource for Pennsylvania Residents 2Health News:CCA Industries, Inc. Declares Its Seventeenth Consecutive Dividend 2Health News:NYC first: Complex aneurysm treated using new fenestrated endograft stent 2
(Date:7/10/2014)... July 10, 2014  BC Technical, the largest nationwide, ... America , Inc., a leading provider of Siemens Nuclear ... long-term agreement naming BC Technical as the authorized provider ... MiE and BC Technical announced today that the ... BC Technical as the service and systems provider for ...
(Date:7/10/2014)... --  Ventana Medical Systems, Inc.  (Ventana), a member of ... an agreement with Merck KGaA, Darmstadt, Germany ... the United States and ... division on the development and commercialization of a companion ... diagnostic assays. In alignment with Merck KGaA,s strategic approach ...
(Date:7/10/2014)... Israel , July 10, 2014   ... Diabetes Management Solution, today announced the appointment of ... independent member of its Board of Directors. ... legal and business experience to LabStyle as an ... and legal and corporate governance expert. He currently ...
Breaking Medicine Technology:BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4
... Combines BchiVac V-500 with Vacuum ... Efficiently controls vacuum levels from ... pump designed to handle most vacuum applications. ... up to two rotary evaporators Laboratory ...
... Combines BchiVac V-500 with Vacuum Controller V-800 ... mechanism turns V-500 on and off as needed to ... is a powerful PTFE membrane vacuum pump designed to ... suited for use with up to two rotary evaporators ...
Universal vacuum pump (capacity 34 L/min, 8 mbar vacuum abs.)...
... a new addition to the powerful PTFE membrane ... pump can achieve an ultimate vacuum of 1 ... Applications For use with vacuum ... Distillation applications from lab size up to industrial ...
Medicine Products: