Navigation Links
Survivors of Childhood Cancers at Higher Risk for Secondary Cancer

According to a recent study published in February 21 Journal of the National Cancer Institute; long-term survivors of childhood cancer// are at a higher risk of developing a secondary cancer than the general population.

Treatments for childhood cancer have resulted in a current overall cure rate of over 70 percent. Previous studies have shown that these survivors are specifically at a higher risk of secondary sarcomas, such as soft tissue sarcomas and osteosarcoma. Radiation therapy is associated with secondary sarcomas, but other specific risk factors are largely unknown.

Tara Henderson, M.D., of the University of Chicago Department of Pediatrics, and colleagues examined the incidence of secondary sarcomas and the risk factors associated with that risk among the 14,372 participants in the Childhood Cancer Survivor Study.

Overall, there were 751 second cancers diagnosed among the participants, 108 of which were secondary sarcomas such as soft tissue sarcoma, malignant peripheral nerve sheath tumors, and osteosarcoma. These sarcomas were diagnosed an average of 11 years after patients were diagnosed with their primary cancer.

The authors found that patients with secondary sarcomas were more likely to have received primary radiation therapy; to have received higher doses of drugs called anthracyclines or alkylators; to have had a primary diagnosis of soft tissue sarcoma, bone tumor, or Hodgkin lymphoma; to have a family history of cancer; or to have a history of other second cancers.

The risk of a secondary sarcoma was ninefold higher among childhood cancer survivors than the general population. The authors calculated that the excess number of cases of secondary sarcomas among childhood cancer survivors over those in the general population is 32.5 cases per 100,000 person-years of follow-up.

"As the childhood cancer survivor population ages and expands in number, clinicians and researchers must carefully iden tify patients who are at risk for secondary morbidities, particularly for secondary cancers," the authors write. "Diagnosis of a sarcoma can sometimes be elusive because symptoms are often nonspecific."

Source-Eurekalert
PRI
'"/>




Related medicine news :

1. Breast Cancer Survivors Worry About Infertility
2. Breast Cancer Survivors Worry About Infertility
3. An Incentive For Breast Cancer Survivors
4. Better Care Required for Breast Cancer Survivors
5. Exercising Good For Stroke Survivors
6. Tsunami Survivors Face Pneumonia Threat
7. Survivors of childhood cancer may have long-term health problems
8. Encephalitis Survivors Face The Risk Of Becoming Disabled
9. Socialization A Serious Trouble For Childhood Cancer Survivors
10. Pakistani Quake Survivors Face Outbreak Of Diarrhea
11. Chronic Post-Traumatic Stress Disorder (PTSD) Risk In Young Natural Disaster Survivors
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... 27, 2016 , ... TherapySites, the leading website ... Tennessee Counseling Association. This new relationship allows TherapySites to continue to ... adding exclusive benefits and promotional offers. , "TCA is extremely excited about this ...
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... transport experience for the millions of people who require these medical transport services ... industry through the use of technology. Now, SmartEMS has put forth an industry-changing ...
(Date:6/26/2016)... ... 27, 2016 , ... Quality metrics are proliferating in cancer care, and are ... the eye of the beholder, according to experts who offered insights and commentary in ... Managed Care. For the full issue, click here . , For the American ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Pixel Film Studios ... X. , "Film editors can give their videos a whole new perspective by using ... - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different ...
(Date:6/26/2016)... ... ... a legally blind and certified personal trainer is helping to develop a weight loss fitness ... to fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the ... (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, ... Global Forecast to 2021" report to their offering. ... pharmaceutical excipients market is projected to reach USD 8.1 ... the forecast period 2016 to 2021. ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at www.diabetesscholars.org by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
Breaking Medicine Technology: