Navigation Links
Surprising Interaction Between Genes, Gender, and Hypertension

ments. For example, men normally have slightly higher BP readings than women.

Accounting for these differences, the researchers set out to test their hypothesis that the influence of genes on blood pressure and hypertension varies with a patient’s gender. Ernst Beutler, M.D., of The Scripps Research Institute Department of Molecular and Experimental Medicine, organized a blood sample collection over a two-year period in order to prepare genomic DNA from the patients’ white blood cells. The researchers then focused on the genetic profiles, or genotypes, of more than 1,200 men and women whose systolic (the higher number in a BP reading) and diastolic (lower number) measurements fell at the extreme – highest and lowest – percentiles of distribution.

The study yielded 48 different genetic variations, or polymorphisms, on 35 different genes that encode proteins involved in blood pressure regulation. Thirty-three of the genes were on autosomes (chromosomes found in both sexes), and two were on the “X-linked” or sex chromosomes.

“Of the 35 genes, we found six genes that were quite different in the frequency of variation between people of either sex who had extremely high or low blood pressure,” said O’Connor.

Several diseases are caused by a variation on a single gene on the chromosome, called a single nucleotide polymorphism (SNP, pronounced “snip”). Examples of so-called SNP diseases are sickle-cell anemia and Huntington’s disease, where a single variant or mutation has a dramatic effect.

In contrast to these single-gene-specific diseases, the UCSD researchers observed more subtle variants on six different genes, indicating that multiple genes can contribute to high blood pressure. “We discovered that there’s more than one gene at work in hypertension,” said O’Connor, adding that the team was surprised to find that these SNPs appear to affect men and women differently.

Among the gene variants, each w
'"/>




Page: 1 2 3

Related medicine news :

1. Surprising Cystic Fibrosis Finding That Could Be A Helpful Treatment Option
2. Blood Pressure Levels Across The Globe Show Surprising Drop
3. Tamoxifen Discontinuation Rates Surprisingly High
4. Increases in Autism Rates Not Surprising to Education Expert
5. Rush Study Shows That Interactions with Friends and Family Prevents Damaging Effects of Alzheimers disease
6. Cancer Patients are at High Risk for Potential Drug Interactions
7. Scientists Discover Rare ‘gene-for-gene’ Interaction That Helps Bacteria Kill Their Hot
8. Link Between Infection And Heart Disease
9. Prescription Drug Use Varies Widely Between States
10. Wait Between Pregnancies
11. Link Between Migraines and Behavioral Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Surprising Interaction Between Genes Gender and Hypertension

(Date:6/29/2015)... ... June 29, 2015 , ... Assurex Health, ... with certain neuropsychiatric and chronic pain conditions, has announced appointments to three key ... include: Peter Donato, Senior Vice President, Chief Financial Officer; Craig S. Lewis, Senior ...
(Date:6/29/2015)... ... , ... The world’s fastest and highest flying production aircraft, the SR-71 Blackbird, ... Virginia. This iconic, supersonic stealth plane will become the focal point of the Museum’s ... ceiling of a historic train station is perhaps one of the most unconventional presentations ...
(Date:6/29/2015)... ... June 29, 2015 , ... Celebrities have many skincare secrets, and skin ... all summer long and beyond. People don’t have to be famous to have ... process, maintain an even skin tone, avoid breakouts, and take skin health and wellness ...
(Date:6/29/2015)... PAUL, Minn. (PRWEB) , ... June 29, 2015 ... ... , an HVAC and plumbing company serving the Twin Cities area, provides money-saving ... overall energy efficiency strategies for Twin Cities’ residents, addressing water conservation and other ...
(Date:6/29/2015)... FL (PRWEB) , ... June 29, 2015 , ... Before launching the next product to ... products day in and day out. One simple question was asked: “What do you ... a pump. BPI used this information to create the next generation of pre-training powders ...
Breaking Medicine News(10 mins):Health News:Assurex Health Names Executives to Posts as CFO, CMO and VP/Clinical Operations 2Health News:Assurex Health Names Executives to Posts as CFO, CMO and VP/Clinical Operations 3Health News:SR-71 Prepares for Flight to Science Museum of Virginia 2Health News:Skin Guru Shares Celebrity FACE Secrets For Summer-Proofing The Skin 2Health News:Skin Guru Shares Celebrity FACE Secrets For Summer-Proofing The Skin 3Health News:Save Energy: MSP Plumbing, Heating & Air Endorses Efficiency 2Health News:Save Energy: MSP Plumbing, Heating & Air Endorses Efficiency 3Health News:The All-New PUMP HD™ by BPI Sports is Here to Energize Your Workouts 2
... Texas M. D. Anderson Cancer Center have found that ... growth factor expression are associated with poor survival in ... presented in a poster session today at the Society ... , Sex cord-stromal ovarian tumors are rare, accounting ...
... 5 Stephen H. Schneider, Ph.D.,professor of Environmental ... , a,climatologist and cancer survivor who shared the ... Gore, will be the keynote speaker at the ... FireSky Hotel in,Scottsdale. The conference attracts health care ...
... CINCINNATI, Feb. 5 LCA-Vision Inc. (Nasdaq: ... services under the Lasik Plus (R) brand, announces that ... Officer Michael J. Celebrezze will hold a conference call ... a.m. Eastern time to discuss management,s plan to drive ...
... Mich. --- Nearly 70 percent of minority women agree ... of the key findings of a Michigan State University ... breast cancer screenings. , The study of 341 Arab-American, ... of medical mistrust and assess the impact on whether ...
... Inc. (Pink Sheets: SYNJ) reports that it has engaged in ... the marketing campaign for the acquisition of and/or the start ... the "Director of Marketing" will be to coordinate and develop ... doctors, hospitals, and businesses in the specific location of each ...
... Tomorrow, millions of Americans will wear red to highlight ... as many women die from heart disease as breast cancer in ... primary care doctors still don,t know that heart attacks kill more ... women to continue wearing red once a week, to help sound ...
Cached Medicine News:Health News:Angiogenesis linked to poor survival in patients with rare type of ovarian cancer 2Health News:Nobel Peace Prize Winner Stephen Schneider Keynotes Annual Conference of Community Oncologists 2Health News:Nobel Peace Prize Winner Stephen Schneider Keynotes Annual Conference of Community Oncologists 3Health News:Nobel Peace Prize Winner Stephen Schneider Keynotes Annual Conference of Community Oncologists 4Health News:LCA-Vision to Hold Corporate Update Conference Call and Q&A Session on February 6 2Health News:LCA-Vision to Hold Corporate Update Conference Call and Q&A Session on February 6 3Health News:MSU study finds high level of medical mistrust among minority women impacts quality of health care 2Health News:Syndication Inc. Seeks 'Director of Marketing' for 'Sy-Med Decompression Centers'; BOD Considers Adding a 'Green Energy' New Company Subsidiary to its Ranks 2Health News:'Go Red for Women' Gets Stronger by the Week 2
(Date:6/29/2015)...  New guidelines released today by the American ... for better outcomes to the hundreds of thousands ... each year. Stryker,s Trevo ® Retriever was ... clinical trials that provided data for this development. ... endovascular therapy with stent retrievers for ischemic stroke ...
(Date:6/29/2015)... 29, 2015  Allergan plc (NYSE: AGN ... second quarter 2015 financial results on Thursday, August ... U.S. financial markets. The Company will host a conference ... Time on Thursday, August 6, 2015 to discuss ... call is U.S./ Canada (877) ...
(Date:6/29/2015)... 2015 Axxess , an industry leader ... software vendor accredited by the American Nursing Credentialing Center ... health agencies select the right revenue cycle management (RCM) ... their business. Research by American Health Information ... expect a decrease in productivity of 54.4 - 69 ...
Breaking Medicine Technology:New AHA Guidelines For The Early Management And Treatment Of Stroke Will Change The Standard Of Care For Thousands Of Stroke Patients Each Year 2New AHA Guidelines For The Early Management And Treatment Of Stroke Will Change The Standard Of Care For Thousands Of Stroke Patients Each Year 3Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 2Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 3Axxess Releases eGuide for Home Health Agencies, Revenue Cycle Management: What You Must Do Now - to Succeed! 2
... CRDC ) today announced that Bernard A. Hausen, M.D., ... present a corporate overview and update at the following conferences: ... November 15, 2011 8:00 a.m. ET New York, NY ... 2011 9:30 a.m. New York, NY To access the ...
... 10, 2011 The Medical Oncology Association of ... recently signed an agreement to work together to ... quality and costs of cancer care in Southern ... clinical, reimbursement and distribution services to help health ...
Cached Medicine Technology:Medical Oncology Association of Southern California, Cardinal Health Specialty Solutions Collaborate With Payors to Improve Quality, Costs, Accessibility of Cancer Care 2Medical Oncology Association of Southern California, Cardinal Health Specialty Solutions Collaborate With Payors to Improve Quality, Costs, Accessibility of Cancer Care 3
... has a graphical touch screen display which ... the "touch of a screen." Features ... Touch Screen, Graphical Display, Memory Cards, Gradient ... Format, Intuitive Programmin, Free Instrument Software Upgrade. ...
... compact design for personal use, yet is able to ... to 32 samples simultaneously. It contains a heating cover ... add mineral oil to prevent evaporation of the reaction ... up to 15 steps can be freely connected to ...
PTC-100 cycler with Hot Bonnet heated lid,holds sixty 0.5ml tubes...
Px2 thermal Cycler chassis (requires block). Multiple interchangeable blocks. Gradient capability. Adjustable height heated lid. Outstanding uniformity. Advanced control algorithms for reduced r...
Medicine Products: