Navigation Links
Surprising Interaction Between Genes, Gender, and Hypertension

ments. For example, men normally have slightly higher BP readings than women.

Accounting for these differences, the researchers set out to test their hypothesis that the influence of genes on blood pressure and hypertension varies with a patient’s gender. Ernst Beutler, M.D., of The Scripps Research Institute Department of Molecular and Experimental Medicine, organized a blood sample collection over a two-year period in order to prepare genomic DNA from the patients’ white blood cells. The researchers then focused on the genetic profiles, or genotypes, of more than 1,200 men and women whose systolic (the higher number in a BP reading) and diastolic (lower number) measurements fell at the extreme – highest and lowest – percentiles of distribution.

The study yielded 48 different genetic variations, or polymorphisms, on 35 different genes that encode proteins involved in blood pressure regulation. Thirty-three of the genes were on autosomes (chromosomes found in both sexes), and two were on the “X-linked” or sex chromosomes.

“Of the 35 genes, we found six genes that were quite different in the frequency of variation between people of either sex who had extremely high or low blood pressure,” said O’Connor.

Several diseases are caused by a variation on a single gene on the chromosome, called a single nucleotide polymorphism (SNP, pronounced “snip”). Examples of so-called SNP diseases are sickle-cell anemia and Huntington’s disease, where a single variant or mutation has a dramatic effect.

In contrast to these single-gene-specific diseases, the UCSD researchers observed more subtle variants on six different genes, indicating that multiple genes can contribute to high blood pressure. “We discovered that there’s more than one gene at work in hypertension,” said O’Connor, adding that the team was surprised to find that these SNPs appear to affect men and women differently.

Among the gene variants, each w
'"/>




Page: 1 2 3

Related medicine news :

1. Surprising Cystic Fibrosis Finding That Could Be A Helpful Treatment Option
2. Blood Pressure Levels Across The Globe Show Surprising Drop
3. Tamoxifen Discontinuation Rates Surprisingly High
4. Increases in Autism Rates Not Surprising to Education Expert
5. Rush Study Shows That Interactions with Friends and Family Prevents Damaging Effects of Alzheimers disease
6. Cancer Patients are at High Risk for Potential Drug Interactions
7. Scientists Discover Rare ‘gene-for-gene’ Interaction That Helps Bacteria Kill Their Hot
8. Link Between Infection And Heart Disease
9. Prescription Drug Use Varies Widely Between States
10. Wait Between Pregnancies
11. Link Between Migraines and Behavioral Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Surprising Interaction Between Genes Gender and Hypertension

(Date:11/26/2014)... The family foundation of Best Buy founder, Richard ... Foundation (Meso Foundation), half of which will be specifically ... Program . The focus area of the Richard M. ... organizations that can generate transformational results in education, human ... and chairman emeritus of Best Buy Co., Inc., the ...
(Date:11/26/2014)... Arlington, VA (PRWEB) November 26, 2014 ... Ushma Suvarnakar as the Association’s new director of ... directing the Association’s annual meeting, special events and ... Ushma Suvarnakar to this post,” said AAA Executive ... contagious level of enthusiasm and energy. She was ...
(Date:11/26/2014)... For its December issue , Atlantic Information ... Blue Cross and Blue Shield Plans* interviewed officials at ... the two Blues plans are implementing in order to ... apnea, ranging from brick-and-mortar retail stores to patient data ... rates of a variety of serious disorders, including hypertension, ...
(Date:11/26/2014)... GI for Life announced today, that they ... of their popular nutritional supplements: ColoVite Colon Health ... Discounts of 40% will be offered for a limited ... ColoVite supplement is a scientifically formulated vitamin supplement developed ... easy-to-take colon vitamin with ALL the nutrients associated with ...
(Date:11/26/2014)... (PRWEB) November 26, 2014 Anthropologists ... effectiveness in containing and stopping Ebola, improve international ... in healthcare systems in West Africa. , ... to Stop Ebola: Anthropologists Offer Insights,” will be ... the American Anthropological Association (AAA), Fri., Dec. 5, ...
Breaking Medicine News(10 mins):Health News:Best Buy Founder’s Family Foundation Donates $100,000 to Organization Fighting Deadly Cancer 2Health News:Best Buy Founder’s Family Foundation Donates $100,000 to Organization Fighting Deadly Cancer 3Health News:American Anthropological Association Appoints New Director of Meetings and Conferences: Ushma Suvarnakar 2Health News:AIS Newsletter Reports on Strategies Blues Plans Are Implementing to Combat Sleep Apnea 2Health News:AIS Newsletter Reports on Strategies Blues Plans Are Implementing to Combat Sleep Apnea 3Health News:GI For Life Slashes Prices by 40% on Liposomal Vitamin D3 and ColoVite Colon Health Formula for a Limited Time 2Health News:Anthropologists Release Recommendations, Better Practices to Contain Ebola 2Health News:Anthropologists Release Recommendations, Better Practices to Contain Ebola 3
... developed a fertility predictor test, which enables women to ... or decreasing. This will be particularly useful to women ... best age for child bearing is// reported to be ... of the Sheffield University. But the pressure of modern ...
... School is exploring the beneficial properties of Lactic acid ... is used for fermentation of curd and yogurt, used ... also as applications in saving fish culture system from ... inhibit the binding of HIV virus into the mucous ...
... over safety with regard to the hormone replacement therapy (HRT), another ... from diseases related to the heart. //The risk of a coronary ... who start with the HRT at an younger age, when in ... ,There are no cardiovascular benefits to be seen in the case ...
... Washington University School of Medicine identify yet another reason to ... been found to play a critical role in the development// ... diet have been found to have a low bone mass. ... 18 individuals aged between 33 and 85 years, under a ...
... themselves to come out of the financial crisis they ... British Health secretary as welcomed better financial management ... cutting unnecessary fund wastage. ,The health ... the NHS hospitals will be followed and finance management ...
... gave the all clear to 21 women who had breast ... chances of fighting and surviving the disease//. ,It ... years after she was given a clean chit by the ... Manchester. The said radiologist worked at Trafford General and the ...
Cached Medicine News:Health News:Raw Vegan Diet Promises Lightweight, Healthy Bones 2
(Date:11/26/2014)... 2014  BioScrip ® , Inc. (NASDAQ: BIOS ) ... Executive Officer, will present at the Bank of America Merrill Lynch ... , Date: , , , Wednesday, December 3, 2014 , ... , , , Location: , , , Boca Raton Resort ... Inc. BioScrip, Inc. is a leading national ...
(Date:11/26/2014)... -- Zynerba Pharmaceuticals , Inc., a specialty pharmaceutical ... cannabinoid treatments, today announced that the company will present ... The conference will be held December 2 to 3, ... York . Zynerba,s Chairman and CEO, Armando ... December 2. To listen to a webcast ...
(Date:11/26/2014)... 26, 2014  Aridis Pharmaceuticals, Inc., a biopharmaceutical ... for infectious diseases, announced today the addition of ... key opinion leader in the areas of pneumonia ... Founder and Chief Executive Officer, ... Opal,s extensive experience investigating bacterial toxins and key ...
Breaking Medicine Technology:Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 2Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 3
... Pharmaceuticals, Inc., a privately held drug development company, is ... as Executive Chairman of the Board of Directors. ... important milestone for Tigris Pharmaceuticals, future," said Edmundo Muniz, ... brings to Tigris extraordinary ability and pharmaceutical industry experience ...
... Sept. 28 Sunridge International (OTC Bulletin Board: ... glaucoma and ocular hypertension will be introduced in October ... Presentations have been planned by its Indian ... October 1 – 14.  The company,s Pneumatic Trabeculoplasty (PNT), ...
Cached Medicine Technology:Tigris Pharmaceuticals Appoints Neil Flanzraich to Executive Chairman of the Board 2Tigris Pharmaceuticals Appoints Neil Flanzraich to Executive Chairman of the Board 3Sunridge to Introduce Their PNT Treatment for Glaucoma to Medical Personnel in India 2
The 96 PW is an intelligent full microplate washer with a 96 needle wash head washing all wells simultaneously. This instrument gives high throughput and outstanding washing efficiency....
Stat Fax 2600 is fully automatic microplate washer....
... 1575 immunowash microplate washer ... needle position to perform ... maximize wash efficiency. This ... choice of wash that ...
... LMW Automated Microplate ... choice for any laboratory. ... sensor allows a precise ... residual volume, digitally controlled ...
Medicine Products: