Navigation Links
Surprising Interaction Between Genes, Gender, and Hypertension

ments. For example, men normally have slightly higher BP readings than women.

Accounting for these differences, the researchers set out to test their hypothesis that the influence of genes on blood pressure and hypertension varies with a patient’s gender. Ernst Beutler, M.D., of The Scripps Research Institute Department of Molecular and Experimental Medicine, organized a blood sample collection over a two-year period in order to prepare genomic DNA from the patients’ white blood cells. The researchers then focused on the genetic profiles, or genotypes, of more than 1,200 men and women whose systolic (the higher number in a BP reading) and diastolic (lower number) measurements fell at the extreme – highest and lowest – percentiles of distribution.

The study yielded 48 different genetic variations, or polymorphisms, on 35 different genes that encode proteins involved in blood pressure regulation. Thirty-three of the genes were on autosomes (chromosomes found in both sexes), and two were on the “X-linked” or sex chromosomes.

“Of the 35 genes, we found six genes that were quite different in the frequency of variation between people of either sex who had extremely high or low blood pressure,” said O’Connor.

Several diseases are caused by a variation on a single gene on the chromosome, called a single nucleotide polymorphism (SNP, pronounced “snip”). Examples of so-called SNP diseases are sickle-cell anemia and Huntington’s disease, where a single variant or mutation has a dramatic effect.

In contrast to these single-gene-specific diseases, the UCSD researchers observed more subtle variants on six different genes, indicating that multiple genes can contribute to high blood pressure. “We discovered that there’s more than one gene at work in hypertension,” said O’Connor, adding that the team was surprised to find that these SNPs appear to affect men and women differently.

Among the gene variants, each w
'"/>




Page: 1 2 3

Related medicine news :

1. Surprising Cystic Fibrosis Finding That Could Be A Helpful Treatment Option
2. Blood Pressure Levels Across The Globe Show Surprising Drop
3. Tamoxifen Discontinuation Rates Surprisingly High
4. Increases in Autism Rates Not Surprising to Education Expert
5. Rush Study Shows That Interactions with Friends and Family Prevents Damaging Effects of Alzheimers disease
6. Cancer Patients are at High Risk for Potential Drug Interactions
7. Scientists Discover Rare ‘gene-for-gene’ Interaction That Helps Bacteria Kill Their Hot
8. Link Between Infection And Heart Disease
9. Prescription Drug Use Varies Widely Between States
10. Wait Between Pregnancies
11. Link Between Migraines and Behavioral Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Surprising Interaction Between Genes Gender and Hypertension

(Date:8/23/2014)... Cardiomyopathy (heart muscle disease) is the ... (the heart muscle) for any reason, usually leading ... and peripheral edema (swelling of the legs). People ... forms of irregular heart beat and sudden cardiac ... dilated cardiomyopathy. , Clinical trial report, “Cardiomyopathy Global ...
(Date:8/23/2014)... 23, 2014 GranuFlo lawsuit ( ... and NaturaLyte dialysis concentrate recall continue to mount ... District Court, District of Massachusetts, Bernstein Liebhard LLP ... by the U.S. Judicial Panel on Multidistrict Litigation ... are pending in the proceeding. In July, the ...
(Date:8/23/2014)... (PRWEB) August 23, 2014 "When men ... comes into contact with the dirty water inside the ... seat itself," said one of two inventors from Naugatuck, ... germs, we developed this protective device." , They developed ... toilet surfaces, including the water, bowl and seat. This ...
(Date:8/23/2014)... On Monday, August 18th, The New ... suffered by Community Health Systems, which operates over 200 ... records containing Personally Identifiable Information (PII) like names, phone ... was engaged to investigate the incident, the belief is ... cyber attackers based in China, who they say are ...
(Date:8/23/2014)... Viejo, California (PRWEB) August 23, 2014 Pixel ... and themes, announced today the release of ProIntro Vol.3, a ... customize a fresh and professional tile just by dragging ProIntro ... Film Studios. "ProIntro Vol.3 is a definite time saver and ... an intro pack with 30 beautifully designed titles made with ...
Breaking Medicine News(10 mins):Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 2Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 3Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 4Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 4Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 2Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 3Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 4Health News:A new plugin was announced today, ProIntro Vol.3 from Pixel Film Studios for Final Cut Pro X 2
... a woman,s eggs to deteriorate in quality with age, and ... choose an egg -- out of a stash of roughly ... the ovary be influenced to pick a "good" quality egg ... questions are much on the mind of fertility researcher Teresa ...
... of Oregon chemist Shih-Yuan Liu have successfully synthesized ... and isostructural to the fundamentally important benzene molecule. ... research and materials science, the boron-nitrogen substituted analogues ... areas. , In the Journal of the ...
... the odds of this cluster of heart risk factors, experts ... of developing metabolic syndrome -- a group of factors linked ... five common gene variations, researchers say. , But one additional ... , People with metabolic syndrome run four times the ...
... to 75 generic drugs at no cost ... for ... copays and coinsurance on 75 generic drugs that are used to,treat common ... help our members become more actively involved in their,health care. The program ...
... According to a recent,survey from the Deloitte Center ... percent of Americans are financially prepared for their future,health ... of consumers are,completely satisfied with their health plans. As ... respond to consumers, demand for,increased access to online tools, ...
... Processing Technology offers insight to fresh food ... ... in fresh tomatoes has resulted in a nationwide concern for,consumers unfamiliar with ... packaged commercially,via heat processing are still safe to eat. Unfortunately heat changes ...
Cached Medicine News:Health News:New photo 'op' for ovaries may solve some mysteries of infertility 2Health News:Researchers confirm benzene-like electron delocalization of important molecule 2Health News:Metabolic Syndrome May Be in the Genes 2Health News:Independence Blue Cross Waives Copays for Generics Used to Treat Certain Chronic Conditions 2Health News:Independence Blue Cross Waives Copays for Generics Used to Treat Certain Chronic Conditions 3Health News:Independence Blue Cross Waives Copays for Generics Used to Treat Certain Chronic Conditions 4Health News:As Consumers Feel Financial Burden of Increasing Health Care Costs, Health Plans Have Opportunity to Address Unmet Consumer Needs and Become Trusted Advisors 2Health News:As Consumers Feel Financial Burden of Increasing Health Care Costs, Health Plans Have Opportunity to Address Unmet Consumer Needs and Become Trusted Advisors 3Health News:As Consumers Feel Financial Burden of Increasing Health Care Costs, Health Plans Have Opportunity to Address Unmet Consumer Needs and Become Trusted Advisors 4Health News:Ultra-High Pressure Processing Eliminates Salmonella in Fresh Tomatoes 2
(Date:8/22/2014)... HILL, N.C. , Aug. 22, 2014  As ... the healthcare sector, many leaders in this area are ... The Medical Affairs Consortium at Best ... a forum for sharing insights about the key challenges ... creating and sharing solutions through three virtual roundtable discussions ...
(Date:8/22/2014)... Aug. 22, 2014 Research and Markets ... and Chinese Intravenous Catheter Industry Report 2014" report ... Chinese Intravenous Catheter Industry Report 2014 is a professional ... global intravenous catheter industry with a focus on the ... of the industry including definitions, classifications, applications and industry ...
(Date:8/22/2014)... 2014  - MediaLINC ... Today Lincor announced general availability of MediaLINC ... a range of education, entertainment and clinical content direct ... http://photos.prnewswire.com/prnh/20140822/702945) , " Lincor has ... patient engagement to bedside smart devices, " comments ...
Breaking Medicine Technology:Best Practices' Medical Affairs Consortium Survey Has Achieved Strong Participation 2Global and Chinese Intravenous Catheter Industry Report 2014 2Lincor Unveils Next Generation TV-based Patient Engagement Solution 2
... Meeting in Salt ... Lake City, ... that they have identified specific genetic markers,for scoliosis. The data from this ... spinal curve progression in,patients with Adolescent Idiopathic Scoliosis., This groundbreaking research ...
... 11 /PRNewswire/-- Cerimon,Pharmaceuticals, Inc., announced today positive results ... topical 15 mg (1%) diclofenac sodium,patch. The multi-center ... Obtain Relief Topically) study evaluated the safety and ... pain due to acute,mild-to-moderate ankle sprains. The study ...
Cached Medicine Technology:Researchers at Axial Biotech Develop a DNA Test for Scoliosis 2Cerimon Pharmaceuticals Announces Positive Results from a Phase II Clinical Study of Its Diclofenac Sodium Patch for Acute Pain 2Cerimon Pharmaceuticals Announces Positive Results from a Phase II Clinical Study of Its Diclofenac Sodium Patch for Acute Pain 3
Titanium hoskin suture tying forceps, 4.75"....
Barraquer straight tying forceps....
This standard tying forcep is curved with 5mm titanium coated platforms. Length 85 mm....
Catalano curved tying forcep has 6 mm V-grove tying platform. Overall length 100 mm....
Medicine Products: