Navigation Links
Sub-Saharan Africans With HIV May Achieve Favorable Levels of ART Adherence

A review of previous studies suggests that favorable levels of antiretroviral therapy adherence can be reached among HIV-infected patients in sub-Saharan Africa,// while adherence remains a concern in North America.

Antiretroviral therapy (ART) has improved the health of many human immunodeficiency virus (HIV) positive individuals who otherwise would have died. However, treatment effectiveness relies on sustained adherence, which is a serious challenge to those receiving ART, according to background information in the article. The regimens are often complicated, can include varying dosing schedules, dietary restrictions, and adverse effects. Consistently high levels of adherence are necessary for reliable viral suppression and prevention of resistance, disease progression, and death. There has been concern that African patients, many of whom live in poverty and lack formal education, will have suboptimal adherence to ART.

Edward Mills, Ph.D., M.Sc., of the Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada, and colleagues conducted a review of available ART adherence data in both Africa and a resource-rich setting, North America, to determine the level of adherence in emerging African treatment programs relative to the more established North American programs. Eleven electronic databases were searched along with major conference abstract databases (inclusion dates: inception of database up until April 18, 2006) for all English-language articles and abstracts; and researchers and treatment advocacy groups were contacted.

Thirty-one studies from North America and 27 studies from sub-Saharan Africa were included. African studies represented 12 sub-Saharan countries. Of the North American studies, 71 percent used patient self-report to assess adherence; this was true of 66 percent of African assessments. The researchers found that North American studies (17,573 patients total) yielded a pooled estimat e of 55 percent of the populations achieving adequate levels of adherence and African studies (12,116 patients total) yielded a pooled estimate of 77 percent, indicating a higher level of ART adherence in Africa.

“The findings from this systematic review and meta-analysis suggest that ART adherence among sub-Saharan African patients in early treatment programs are favorable, although it should be noted that the complexity of treatment regimens is potentially greater in North America, which should be considered when interpreting the data,” the authors write.

The researchers add that the barriers to adherence among impoverished individuals in North America appear to be due to poor patient-clinician relationships, untreated depression, substance abuse, and other factors that are common among poor individuals in the North America setting rather than poverty itself.

“We have shown that there are patients in both settings that have suboptimal adherence and that factors beyond poverty play an important role. Clinicians should therefore proactively inquire with patients about current barriers or facilitators of adherence to HIV medications,” they write.

(Source: Newswis)
'"/>




Related medicine news :

1. HIV among IDUs On The Rise In The Sub-Saharan Africa Region
2. Africans Should Take Their Traditional Medicine Very Seriously
3. South Africans Turn to Natural Remedies for Treating Erectile Dysfunction
4. Human Genome Project Achieves Technological Triumph
5. Calcium Supplements May Not Be Useful After A Certain Threshold Is Achieved
6. Boost of Memory Can Be Achieved Through Physical Activity
7. India To Highlight Its Scientific Achievements
8. NHS To Achieve Waiting Figure Target By 2008
9. Better Weight Management Can be Achieved By Increased Intake Of Fibre & Fruits
10. A Village in Madhya Pradesh Achieves Total Sanitation
11. Major Change Needed to Achieve Dignified Care for Older People
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... ... May 24, 2016 , ... The Radiosurgery ... practice of radiosurgery, is recognizing five medical residents and students for their outstanding ... radiotherapy (SBRT). The awards will be presented at the 2016 SRS/SBRT Scientific Meeting ...
(Date:5/24/2016)... ... May 24, 2016 , ... The number of ... people, or 10% over last year, according to data in the forthcoming AIS’s ... was comparatively stable, with a slight decrease in risk-based groups and a slight ...
(Date:5/24/2016)... ... May 24, 2016 , ... Bio-Logic Aqua® Research Water ... years and a trainer for Ageless Grace ( http://www.agelessgrace.com ) to discuss healthier ... May 16, 2016. , Formerly a Northwestern University Literature Professor, Kinst gravitated to ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... WaterAid launched the #perioddrama campaign ... by more than 1 billion women around the world who do not have access to ... from across the US about their dread of #perioddrama. The (sometimes hilarious) results help shine ...
(Date:5/24/2016)... ... May 24, 2016 , ... In light of recent heavy flooding in ... of contaminated well water throughout the Houston area. , Heavy floodwaters have led to ... exposed to contaminants. Residents may not even be aware of the contamination of their ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... , May 23, 2016 ... "Patient Handling Equipment Market by Product (Wheelchair, Scooters, ... Care (Bariatric Care, Critical Care, Wound), Accessories (Lifting, ... Forecast to 2021", published by MarketsandMarkets, the patient ... 17.18 Billion by 2021 at a CAGR of ...
(Date:5/23/2016)... 2016 According to market ... Growth and Demand Forecast to 2022 - Industry ... Application (Drug Discovery and Development, Proteomics, Clinical Testing, ... Science and Biotechnology, Academic and Research Institute, Hospitals ... global mass spectrometry market was valued ...
(Date:5/23/2016)... , UAE, May 23, 2016 ... importance of Precision Medicine and the role of ...   The First International Conference of VPS-Penn ... the distinguished patronage and presence of Sheikh Nahyan bin Mubarak ... focused in Precision Medicine, which helps provide personalized medicine and ...
Breaking Medicine Technology: