Navigation Links
Study Refutes Theory on HIV's Effect on White Blood Cells

A study conducted by researchers at Imperial College London refutes the long-standing "runaway" theory on how HIV slowly depletes the bodys capability to fight infection by attacking T helper cells, a class of white blood cells that co-ordinate the immune defences.

Scientists have for long been puzzled as to why this process of depletion of is so slow, often taking a decade or more.

According to the "runaway" hypothesis, T cells infected by HIV produce more HIV virus particles that activate more T cells, leading to an uncontrolled cycle of cell activation, infection, HIV production, and cell destruction.

But using mathematical model of the process by which T cells are produced and eliminated, the researchers have shown that if the runaway theory was correct, T helper cell numbers would fall to very low levels over a number of months, not years.

He said: "Scientists have never had a full understanding of the processes by which T helper cells are depleted in HIV, and therefore theyve been unable to fully explain why HIV destroys the bodys supply of these cells at such a slow rate," said Jaroslav Stark, Professor of Mathematics at Imperial College London.

"Our new interdisciplinary research has thrown serious doubt on one popular theory of how HIV affects these cells, and means that further studies are required to understand the mechanism behind HIVs distinctive slow process of cellular destruction," he added.

The researchers believe that one possible explanation for the slow pace of the process may be that the virus slowly adapts itself over the course of the infection.

They, however, stress the need for further analysis is to verify the alternative theory.

"If the specific process by which HIV depletes this kind of white blood cells can be identified, it could pave the way for potential new approaches to treatment," said Professor Stark.

The study has been published in PLoS Medicine.


'"/>




Related medicine news :

1. Tomato Sauce reduces Cancer Risk- Study
2. Study on obesity and heart failure
3. National Lung Study in the process
4. Study casts doubt on keyboard ills
5. Study reveals how stress can make you sick
6. Study reveals how stress can make you sick
7. Study supports vegetable diet
8. Study to look at early surgery to treat epilepsy
9. Its Never Too Late to Stop Smoking,Study Finds
10. New Technique to Study Infants Brain.
11. Groundbreaking Study Gives Hope For Patients With Kidney Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/15/2018)... ... September 14, 2018 , ... ... campaign will showcase the innovative work being done within rare diseases research, diagnostics, ... for those living with rare diseases. , Clay Matthews, Super ...
(Date:9/13/2018)... Mont. (PRWEB) , ... September 13, 2018 , ... Pulsara ... Annual Health IT + Revenue Cycle Conference on September 19-22 in Chicago. Dr. ... separate panels as well as a talk titled, “Your Clinical Communication & Collaboration (CC&C) ...
(Date:9/12/2018)... (PRWEB) , ... September 13, 2018 , ... Donaldson Plastic ... companies, as well as Columbus Business First's Fast 50 list of central Ohio's fastest ... with a 3-year growth rate of 81 percent. It is the only medical practice ...
(Date:9/7/2018)... ... September 07, 2018 , ... ... , the only OSHA authorized OTI Education Center headquartered in Northern California, is ... who feel they have experienced retaliation in response to engaging in activity protected ...
(Date:9/2/2018)... ... September 02, 2018 , ... Eaton Hotel in Washington, DC ... itself, which opened this week, inspires creativity and innovation among its guests, whether ... Hotel DC currently features 209 hotel rooms, a wellness center, a radio station, ...
Breaking Medicine News(10 mins):
(Date:9/15/2018)... ... September 14, 2018 , ... ... sequencing to enable greater library coverage. However, severe gaps and limitations associated ... remain. , Multiplexed phage display provides a simple, robust, and seamless high-throughput-ready ...
(Date:9/13/2018)... ... , ... Dr. Rod J. Rohrich is pleased to announce that registration is ... experts from around the world, will take place from March 22nd and 23rd, 2019. ... anatomy to complex surgical procedures and detailed analysis of revision rhinoplasty . Formats ...
(Date:9/12/2018)... ... September 12, 2018 , ... ... of Express Surveys as part of its Population Engage patient experience suite. ... feedback from patients, giving the provider organization a wealth of strategic and tactical ...
Breaking Medicine Technology: