Navigation Links
Study Refutes Theory on HIV's Effect on White Blood Cells

A study conducted by researchers at Imperial College London refutes the long-standing "runaway" theory on how HIV slowly depletes the bodys capability to fight infection by attacking T helper cells, a class of white blood cells that co-ordinate the immune defences.

Scientists have for long been puzzled as to why this process of depletion of is so slow, often taking a decade or more.

According to the "runaway" hypothesis, T cells infected by HIV produce more HIV virus particles that activate more T cells, leading to an uncontrolled cycle of cell activation, infection, HIV production, and cell destruction.

But using mathematical model of the process by which T cells are produced and eliminated, the researchers have shown that if the runaway theory was correct, T helper cell numbers would fall to very low levels over a number of months, not years.

He said: "Scientists have never had a full understanding of the processes by which T helper cells are depleted in HIV, and therefore theyve been unable to fully explain why HIV destroys the bodys supply of these cells at such a slow rate," said Jaroslav Stark, Professor of Mathematics at Imperial College London.

"Our new interdisciplinary research has thrown serious doubt on one popular theory of how HIV affects these cells, and means that further studies are required to understand the mechanism behind HIVs distinctive slow process of cellular destruction," he added.

The researchers believe that one possible explanation for the slow pace of the process may be that the virus slowly adapts itself over the course of the infection.

They, however, stress the need for further analysis is to verify the alternative theory.

"If the specific process by which HIV depletes this kind of white blood cells can be identified, it could pave the way for potential new approaches to treatment," said Professor Stark.

The study has been published in PLoS Medicine.


'"/>




Related medicine news :

1. Tomato Sauce reduces Cancer Risk- Study
2. Study on obesity and heart failure
3. National Lung Study in the process
4. Study casts doubt on keyboard ills
5. Study reveals how stress can make you sick
6. Study reveals how stress can make you sick
7. Study supports vegetable diet
8. Study to look at early surgery to treat epilepsy
9. Its Never Too Late to Stop Smoking,Study Finds
10. New Technique to Study Infants Brain.
11. Groundbreaking Study Gives Hope For Patients With Kidney Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... February 24, 2017 , ... Houston ... at his office, Antoine Dental Center. Currently, patients can get single dental implants ... apply, but patients can learn more about these offers by contacting Antoine Dental ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Smart Machine Age ... Oxford University predict that 47 percent of all jobs in the United States may ... and “successful.” The day of the aggressive know-it-all who steamrolls over colleagues is drawing ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now have the ability ... total control over position, rotation, distortion, edge softness, edge blur, chromatic aberration, individual glass ... , With ProGlass Prism users are given the tools and effects to generate ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Radiology Business Management ... radiology marketing programs at the annual Building Better Radiology Marketing Programs conference, ... Hotel in Fort Worth, Texas. Nine awards are given out in five categories. They ...
(Date:2/23/2017)... ... February 23, 2017 , ... On February 22, 2017 the ... to withdraw previous guidance issued by the Obama Administration requiring schools to ... May 2016 by the Obama Administration came in response to a growing number ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... 2017 Research and Markets has announced the ... - 2016" report to their offering. ... The latest research Oesophageal Cancer Drugs ... benchmarks in the global Oesophageal Cancer market. The research ... the key drugs marketed for Oesophageal Cancer and their clinical attributes? ...
(Date:2/23/2017)... Calif. , Feb. 23, 2017 ... company focused on the development and commercialization of ... pain, announced that it will release fourth quarter ... Thursday, March 2nd, 2017. AcelRx management will host ... Time (1:30 p.m. Pacific Time) on March 2 ...
(Date:2/23/2017)... York , February 23, 2017 ... arising from increasing caseload for varicose veins in their ... the globe are prompting the adoption of endovenous laser ... on global endovenous laser therapy market, published ... aftereffects of lifestyle choices and consequences of obesity have ...
Breaking Medicine Technology: