Navigation Links
Study Refutes Theory on HIV's Effect on White Blood Cells

A study conducted by researchers at Imperial College London refutes the long-standing "runaway" theory on how HIV slowly depletes the bodys capability to fight infection by attacking T helper cells, a class of white blood cells that co-ordinate the immune defences.

Scientists have for long been puzzled as to why this process of depletion of is so slow, often taking a decade or more.

According to the "runaway" hypothesis, T cells infected by HIV produce more HIV virus particles that activate more T cells, leading to an uncontrolled cycle of cell activation, infection, HIV production, and cell destruction.

But using mathematical model of the process by which T cells are produced and eliminated, the researchers have shown that if the runaway theory was correct, T helper cell numbers would fall to very low levels over a number of months, not years.

He said: "Scientists have never had a full understanding of the processes by which T helper cells are depleted in HIV, and therefore theyve been unable to fully explain why HIV destroys the bodys supply of these cells at such a slow rate," said Jaroslav Stark, Professor of Mathematics at Imperial College London.

"Our new interdisciplinary research has thrown serious doubt on one popular theory of how HIV affects these cells, and means that further studies are required to understand the mechanism behind HIVs distinctive slow process of cellular destruction," he added.

The researchers believe that one possible explanation for the slow pace of the process may be that the virus slowly adapts itself over the course of the infection.

They, however, stress the need for further analysis is to verify the alternative theory.

"If the specific process by which HIV depletes this kind of white blood cells can be identified, it could pave the way for potential new approaches to treatment," said Professor Stark.

The study has been published in PLoS Medicine.


Related medicine news :

1. Tomato Sauce reduces Cancer Risk- Study
2. Study on obesity and heart failure
3. National Lung Study in the process
4. Study casts doubt on keyboard ills
5. Study reveals how stress can make you sick
6. Study reveals how stress can make you sick
7. Study supports vegetable diet
8. Study to look at early surgery to treat epilepsy
9. Its Never Too Late to Stop Smoking,Study Finds
10. New Technique to Study Infants Brain.
11. Groundbreaking Study Gives Hope For Patients With Kidney Cancer
Post Your Comments:

(Date:6/27/2016)... NY (PRWEB) , ... June 27, 2016 , ... ... using cutting edge technology to revolutionize the emergency ambulance transport experience for the ... are aware of how Uber has disrupted the taxi industry through the use ...
(Date:6/26/2016)... (PRWEB) , ... June 27, 2016 , ... Quality metrics ... yet in many ways they remain in the eye of the beholder, according to ... a publication of The American Journal of Managed Care. For the full issue, ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Pixel Film Studios ... X. , "Film editors can give their videos a whole new perspective by using ... - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different ...
(Date:6/26/2016)... ... ... blind and certified personal trainer is helping to develop a weight loss fitness plan that ... the two major problems leading the fitness industry today:, , All ... They don’t eliminate all the reasons people quit their exercise program , ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  Guerbet announced today that it has been ... Award . One of 12 suppliers to ... its support of Premier members through exceptional local customer ... commitment to lower costs. ... our outstanding customer service from Premier," says Massimo ...
(Date:6/23/2016)... 2016 Research and Markets has ... Global Analysis (United States, China, Japan, Brazil, United Kingdom, ... their offering. Surgical ... business planners, provides surgical procedure volume data in a ... an in-depth analysis of growth drivers and inhibitors, including ...
(Date:6/23/2016)... , June 23, 2016 ... but it continues to present great opportunities to investors. ... for today: Intrexon Corp. (NYSE: XON ), ... Pharmaceuticals Inc. (NASDAQ: ARNA ), and Regeneron ... about these stocks and receive your complimentary trade alerts ...
Breaking Medicine Technology: