Navigation Links
Study Provides Evidence That Obesity Leads To A More Aggressive Ovarian Cancer

A new study states that the outcome of a woman diagnosed with ovarian cancer might be affected on whether or not she is obese// .

A new study that is to be published in the October 1, 2006 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a journal of the American Cancer Society, states to have found evidence claiming that obesity leads to more aggressive types of ovarian cancer. The researchers have stated that they have found significant differences in the histological types of epithelial ovarian cancer depending on body mass index (BMI). They also explained that in women with advanced disease, a higher BMI might be associated with a reduced survival rates.

Increasing evidence points to the importance of being obese (BMI greater than 30) and overweight (BMI between 25 and 30) in the development and prognosis of several cancers, including breast, uterine and colorectal. Their relationship to ovarian cancer is less well understood.

Almost one in 60 women will develop ovarian cancer during their lifetimes. Most will be diagnosed with advanced disease and 70 percent will die in five years, making it one of the most lethal cancers. There are several types of ovarian cancer, but tumours that begin from surface cells of the ovary (epithelial cells) are the most common type. A few recent studies have shown that obese patients have a worse outcome. Scientists hypothesize that higher mortality associated with obesity may be caused by more aggressive tumours rather than delays in diagnosis.

Andrew J. Li, M.D. of the Cedars-Sinai Medical Centre and Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute and colleagues reviewed data from 216 women with ovarian cancer to identify relationships between obesity, ovarian cancer, tumour biology, and outcome.

Comparison of obese (35 of 216) and ideal weight (108 of 216) women showed 29 percent of obese women and 10 percent of ideal weight women had localized disease. However, obesity was significantly associated with both different cellular characteristics of the tumour and outcome in women with advanced disease.

Obese women were more likely to have mucinous types of tumours and tended to have non-serous types as well.

Though increasing BMI was not associated with differences in treatment for women with advanced disease, a BMI greater than 25 was associated with shorter disease-free survival. In addition, increasing BMI was associated almost linearly increasing risk of mortality.

“This study supports the hypothesis that obesity impacts ovarian cancer mortality by influencing tumour biology, conclude the authors. Additionally, the researchers observed “significant differences in the risk of cancer progression and cancer-related mortality associated with increasing BMI in a fairly 'dose-dependent' fashion.”

Source: EurekAlet.
'"/>




Related medicine news :

1. Tomato Sauce reduces Cancer Risk- Study
2. Study on obesity and heart failure
3. National Lung Study in the process
4. Study casts doubt on keyboard ills
5. Study reveals how stress can make you sick
6. Study reveals how stress can make you sick
7. Study supports vegetable diet
8. Study to look at early surgery to treat epilepsy
9. Its Never Too Late to Stop Smoking,Study Finds
10. New Technique to Study Infants Brain.
11. Groundbreaking Study Gives Hope For Patients With Kidney Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... ... 21, 2017 , ... Westside Dental Associates and its owner, Dr. ... thirty-two years, Dr. Latner has become one of the Los Angeles area’s premier dentists. ... years with all their dental needs,” said Dr. Latner, who was recently named Chairperson ...
(Date:4/21/2017)... ... 2017 , ... Each year, everyone is urged to give back to the ... look forward to a better future. However, supporting the environment should be an everyday ... can be two to five times more polluted than outdoor air, reports the Environmental ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... familiar? These are five common elements between the Obamacare program that most ... control program which uses Warfarin poison to kill hogs. , Like Obamacare, ...
(Date:4/21/2017)... ... April 21, 2017 , ... Indiana Fiber Network, LLC (IFN), ... service to Tele-Media Solutions. IFN is delivering Multi-Gigabit data rates as an ... Solution’s protect transport with 3GB Dual Access Internet access now available in their ...
(Date:4/21/2017)... ... April 21, 2017 , ... MiracleFeet announced today ... years to help end the disability caused by untreated clubfoot in low-income countries. ... Global Clubfoot Initiative to end disability caused by clubfoot worldwide. , ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... NEW YORK , April 19, 2017 ... Surgical drainage devices are tubes used to remove excess ... include, blood, serum, pus, urine, bile or lymph. Surgical ... types of surgery such as orthopedics surgery, cardiovascular surgery, ... device is prophylactic post-surgery to prevent accumulation of fluid ...
(Date:4/19/2017)... The Global Effective Microorganisms (EM) Market ... has covered and analysed the potential of Global Effective Microorganisms ... shares and growth factors. The report identifies and analyses the ... the global market. ... 152 Tables and Figures, 6 Major Company Profiles, spread across ...
(Date:4/19/2017)... 19, 2017  New research provides evidence that an old ... to a study released today that will be presented at ... in Boston , April 22 to 28, ... of Parkinson,s disease, the oral drug levodopa has long been ... But as the disease progresses, the effects of the medication ...
Breaking Medicine Technology: