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Study Offers Hope In Prevention Of Facial Paralysis

an erode into the ear bones and other structures. If the trapped debris grows large enough, it can even cause problems with hearing and balance. Indeed, cholesteatomas can also grow into the nearby facial nerve, causing facial paralysis, or they can erode the nerve’s bony covering, making it dehiscent. This is especially a problem when doctors perform surgery to remove the cholesteatoma, as the facial nerve is now especially vulnerable to injury.

Eligible patients were consecutively enrolled in a prospective database from 1985-2005. From the original database, ultimately 416 ears were identified in which cholesteatoma was diagnosed at the time of surgery. Facial nerve dehiscence was characterized as either present or absent in the tympanic and the mastoid segments of the nerve. Dehiscence in the tympanic segment was then further characterized using the oval window and cochleariform process as landmarks. The presence of cholesteatoma directly adherent to the nerve was noted as were any fistulae to either the cochlea or semi-circular canals. Statistical analysis included the chi-squared test of independence (£q2) to analyze the relationship between age and rate of dehiscence. The £q2 test was also used to analyze the relationship between dehiscence of the facial nerve and inner ear fistula.

Study patients averaged 28 years in age, ranging from 10 months to 81 years. Fifty-seven percent were male, 43 percent were female. A facial nerve dehiscence was found in 78 of the 416 patients (18.8 percent). The most common site of dehiscence centered above the oval window (a middle ear landmark), with 80 percent of dehiscent nerves involving this area. Patients age 18 and under were less likely to have facial nerve dehiscence than older patients. Also, dehiscence of the facial nerve was also found to be associated with inner ear fistulae. Both of these observations were shown to be statistically significant by the £q2 test.

Source: Newwise
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