Navigation Links
Study Finds the Effect of Alcohol and Aspirin in TBI Patients

An estimated 1.5 million people in the United States incur a traumatic brain injury (TBI) every year and 60,000 people die annually from these injuries//. TBI is the ultimate cause of death in 40 percent of all fatal trauma cases. TBI may result from a direct blow to the brain or from the secondary effects of head trauma such as bleeding, swelling, decreased oxygen, or increased pressure on the brain. Intracranial hemorrhage (ICH) or bleeding inside the head is the cause of death in 70-80 percent of patients presenting with TBI.

ICH increases the risk of brain damage, which can lead to serious residual neurological disabilities in surviving patients. Every year, 80,000 to 90,000 people experience the onset of long-term or lifelong disabilities associated with TBI. In the United States today, there are currently as many as 5.3 million TBI survivors living with these disabilities.

There have been many studies dedicated to predicting overall clinical outcome in TBI patients. The factors which have been identified thus far are age, level of consciousness on first admission to the hospital, and degree of injury on computed tomography (CT) scanning. It is known that up to 50 percent all cases of ICH can increase with time, resulting in worsening neurological status and appearance on CT scan.

More than half of the patients brought to the hospital with TBI are intoxicated and many have cardiovascular disease requiring them to be on blood-thinners such as aspirin. Yet no prior studies have examined the potential effects of alcohol and aspirin consumption on worsening ICH in patients with TBI. Researchers at Elmhurst Hospital Center performed a one-year observational study on 150 patients treated at this Level 1 Trauma Center.

Aspirin thins the blood, and reduces the risk of clots forming in key blood vessels, yet can cause bleeding problems in people with certain conditions Theoretically, TBI patients who are aspirin users coul d be prime candidates at risk for increased hemorrhaging associated with aspirin consumption.

When used in excess, alcohol damages brain structure and function. Besides the acute effects of alcohol consumption on the neurological function of the brain, there are physical changes that may result from moderate to heavy drinking of long duration. One concern is brain atrophy, which leaves more room inside the cranium for blood to collect during a brain injury. Alcohol weakens the walls of blood vessels and makes them more susceptible to rupture and bleeding. It is theorized that the combination of these factors can lead to an increase of ICH.

The study included 150 patients with a mean age of 49, admitted to the hospital with ICH after acute TBI. All pertinent patient information including history of blood-thinner usage was recorded. Initial alcohol levels were measured in all patients suspected of intoxication. Other labs were drawn including those used to assess the clotting ability of the blood. All patients underwent two sequential CT scans within 6-12 hours after admission. The CT scans were evaluated by the investigative team and the on-call radiologist for worsening brain hemorrhage. High blood alcohol levels were present in 56.2 percent of the patients. Patients taking aspirin comprised 8.2 percent of this study population.

“Interestingly, we found that neither alcohol nor aspirin were significantly associated with worsening ICH. However increasing age was significantly correlated with worsening hemorrhage,” stated Dr. Smith. Overall outcome was negatively associated with worsening ICH and was measured by mortality (3 percent) and discharges to home (78.1 percent), a rehabilitation center (16.4 percent), or a skilled nursing facility (2.3 percent).

Source-Newswise/
'"/>




Related medicine news :

1. Tomato Sauce reduces Cancer Risk- Study
2. Study on obesity and heart failure
3. National Lung Study in the process
4. Study casts doubt on keyboard ills
5. Study reveals how stress can make you sick
6. Study reveals how stress can make you sick
7. Study supports vegetable diet
8. Study to look at early surgery to treat epilepsy
9. Its Never Too Late to Stop Smoking,Study Finds
10. New Technique to Study Infants Brain.
11. Groundbreaking Study Gives Hope For Patients With Kidney Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and Nutrition ... the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market ... can be easily incorporated into liquid products, while reducing costs to end users. , ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... DevOps and Agile Software Development, has been awarded a contract by the Center ... Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  Caris Life Sciences ® , a leading ... of precision medicine, today announced that St. Jude Medical ... Alliance™ (POA) as its 17 th member. Through ... Crosson Cancer Institute will help develop standards of care ... profiling, making cancer treatment more precise and effective. ...
(Date:10/10/2017)... 2017   West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today shared the results of a study ... the intradermal administration of polio vaccines. The study results ... May 2017 by Dr. Ondrej Mach , Clinical ... Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... WESTWOOD, Mass. , Oct. 4, 2017  According to the Centers ... by the end of October . PhysicianOne Urgent Care is helping communities ... Westchester, NY , by offering no-cost* flu shots through ... , as mandated by certain health insurance regulations. ... The best time to get a flu shot is by ...
Breaking Medicine Technology: