Navigation Links
Studies Find Connection Between Acid Reflux And Esophageal Cancer

In a new study scientists have claimed to find a link between acid reflux and esophageal cancer.// In a recent study that has been published in the Journal of Biological Chemistry, researchers have explained that a specific enzyme found to be significantly higher in cancer cells on their exposure to acid, which could lead to the overproduction of hydrogen peroxide, and there by offer a possible explanation as to how acid reflux might lead to cancer of the esophagus.

The study found that the enzyme NOX5-S is affected by exposure to acid and that it produces stress on cells, activating genes that lead to DNA damage. For the first time, researchers have outlined the signaling pathway from cells damaged by acid, to the progression of esophageal cancer. They believe the same process may happen in the body when cells are exposed to acid reflux. "The role of acid is controversial. But we show that by exposing cells to acid for short periods of time, that affects a particular enzyme, triggering a chain of events that possibly leads to cancer of the esophagus. Now that we have a better understanding of the signaling pathway, we can possibly identify who is at risk of developing cancer by determining the levels of this enzyme," says senior author Weibiao Cao, a researcher at Rhode Island Hospital and an assistant professor of medicine and surgery at Brown Medical School. The study looked at human cancer cells and biopsies from patients with Barrett's esophagus (BE), a condition where cells in the esophagus have been altered by gastroesophageal reflux disease (GERD), or acid reflux. Acid reflux is believed to be a major risk factor for cancer in people with Barrett's esophagus. However, the mechanisms of the progression to cancer have not been fully understood. In this study, researchers found that the enzyme NOX5-S is significantly higher in Barrett's esophageal tissues, which creates a pre-cancerous condition, as we
'"/>




Page: 1 2 3

Related medicine news :

1. Studies On Hearing Loss Discovers New Causes
2. Broccoli Found to Block Cancer Progression In Both Animal and Human Studies
3. Cure For Autism Could Be Established Through Hamster Studies
4. Despite More Studies Researchers Are Still Confound With ADHD
5. Studies Show Brain becomes Less Specialized With Age
6. ISB To Establish Research Chair On Real Estate And Urban Studies
7. Studies Show Combination Drugs As A Poor Substitute For Anti-Coagulants In Stroke
8. Further Studies Needed To Completely Understand About Ventricular Fibrillation
9. Studies Report Mammograms Unsafe
10. Six Indians Win Australian Studies Fellowships
11. Circumcision Studies to Continue Says Health Panel
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Studies Find Connection Between Acid Reflux And Esophageal Cancer

(Date:10/1/2014)... protein beta-amyloid is strongly associated with Alzheimer,s disease; however, ... peptide is the causal agent of the onset and ... confirmation is that beta-amyloid is not harmful when found ... when it self-assembles to form the so-called amyloid fibrils ... beta-amyloid alone, but with multiple ones because each aggregate ...
(Date:10/1/2014)... Physical Sciences Research Council (EPSRC) will focus on ... systems which run, for example, manufacturing plants, power ... , The research will help understand and ... systems behind our critical national infrastructure. , ... (RITICS), based at Imperial College London, is co-ordinating ...
(Date:10/1/2014)... Familylifeinsurancequotes.org has released a new blog post explaining how ... Senior citizens can qualify for affordable term life insurance ... are over 50 years old. Some term life insurance ... , Term life insurance with a simplified issue can ... life insurance during retirement is important for covering funeral ...
(Date:10/1/2014)... Lifeinsurance-policy.com has released a new ... insurance prices for smokers. , Smoking will always have ... quotes is the best method to find affordable coverage. ... who need coverage. , Whole life insurance premiums ... policy. Since the coverage is permanent, the initial ...
(Date:10/1/2014)... FARMINGTON, Conn. (PRWEB) October 01, 2014 ... its company, including a redefined mission and visual ... the power of partnering with them to create ... more agile brand that focuses on empowering customers ... benefits communications. , The crown jewel of the ...
Breaking Medicine News(10 mins):Health News:Laying siege to beta-amyloid, the key protein in Alzheimer's disease 2Health News:£2.5 million to recognize and reduce cyber-attack threats to critical infrastructure 2Health News:Affordable Term Life Insurance - Senior Citizens Can Qualify for Coverage! 2Health News:Affordable Whole Life Insurance Premiums for Smokers! 2Health News:Farmington Company Launches Rebrand and New Positioning 2
... say on whether patients should have to opt in or ... is concerned that, in the proposed summary care record, data ... and this is not being made sufficiently clear to the ... letter to this week's journal. ,"Patients and clinicians ...
... care workers in the United States has risen, so ... ,According to Vanderbilt infectious disease experts Timothy ... should be provided to health care workers with latent ... test, particularly if they meet certain high-risk criteria. ...
... the debate with many others to discuss on the focus ... women.// Instead of giving a conceptual argument on the similarities ... and proved. ,Barres' experience as a female-to-male transgendered ... July 13 issue of Nature rebuking the comments of former ...
... A study led by Australian researchers has discovered a ... binding protein in human airway epithelial cells// that regulates ... researchers had explained in their study that the adipocyte/macrophage ... the uptake by fat cells of fatty acids and ...
... suicide fail to seek help from a doctor or mental ... may find it difficult to obtain adequate// treatment or medication, ... improve access to treatment for people with suicide ideation," said ... Los Angeles and study co-author. "There is a problem with ...
... published in the open access journal Substance Abuse Treatment, Prevention ... regular extra// training treats the alcohol dependent patients better for ... patients treated by trained GPs who abstain from drinking alcohol ... received the basic training alone at the medical school. ...
Cached Medicine News:Health News:Electronic Patient Record "Serious Threat" to Patient Confidentiality 2Health News:Transgender Experience - A Tool to Analyze Gender Difference By Stanford Scientist 2Health News:Transgender Experience - A Tool to Analyze Gender Difference By Stanford Scientist 3Health News:Transgender Experience - A Tool to Analyze Gender Difference By Stanford Scientist 4Health News:Study Says - Blocking 'aP2' Protein Prevents Airway Diseases 2Health News:Many Suicidal Adults Aren't Getting Mental Health Treatment 2
(Date:9/30/2014)... LONDON , Sept. 30, 2014 This report ... Million by the following Product Categories: Enteral Feeding Pumps, Nasogastric ... analytics for the US Canada, Japan , ... Latin America , and Rest of World. ... through 2018. Also, a six-year historic analysis is provided for ...
(Date:9/30/2014)... ROCKVILLE, Md. , Sept. 30, 2014 /PRNewswire/ ... natural way to modernize medicine, announced today the ... line of nutraceuticals developed to address men and ... staying healthy and vibrant into old age while ... line includes three condition-specific, whole-food and herb-based formulas, ...
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... - 2014 Summary Global Markets Direct,s, ... 2014, provides an overview of the Aileron Therapeutics, ... report provides comprehensive information on the current therapeutic ... comparative analysis at various stages, therapeutics assessment by ...
Breaking Medicine Technology:Global Enteral Feeding Devices Industry 2Global Enteral Feeding Devices Industry 3Global Enteral Feeding Devices Industry 4Global Enteral Feeding Devices Industry 5Global Enteral Feeding Devices Industry 6Global Enteral Feeding Devices Industry 7Global Enteral Feeding Devices Industry 8Global Enteral Feeding Devices Industry 9Global Enteral Feeding Devices Industry 10Global Enteral Feeding Devices Industry 11Global Enteral Feeding Devices Industry 12Global Enteral Feeding Devices Industry 13Global Enteral Feeding Devices Industry 14Global Enteral Feeding Devices Industry 15Global Enteral Feeding Devices Industry 16Global Enteral Feeding Devices Industry 17Global Enteral Feeding Devices Industry 18Global Enteral Feeding Devices Industry 19Aileron Therapeutics, Inc. - Product Pipeline Review - 2014 2Aileron Therapeutics, Inc. - Product Pipeline Review - 2014 3
... (Ulleval,University Hospital, Oslo, Norway), lead investigator for the ... provide an update on,the study on Monday the ... be Sir Richard Peto (Professor of Medical,Statistics and ... University of Oxford) Professor Rory Collins (BHF Professor ...
... NEW YORK, July 17 The Michael J. ... in total funding to nine research teams under ... intellectual and financial,resources to help push potential PD ... nearly five million Parkinson,s patients,worldwide., "The discovery ...
Cached Medicine Technology:Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinson's Disease 2Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinson's Disease 3
Dust covers for a variety of Zeiss microscopes...
These objectives have more contrast than the DLL objectives for enhanced contrast with tissue culture specimens. These objectives are designed for use on inverted microscopes and therefore their mark...
... Axiovert 40 inverted ... you have ever expected from a microscope in ... outstanding quality, and functionality. Axiovert 40 has been ... safe as possible thus increasing the efficiency ...
... TE2000E is an advanced inverted microscope for ... imaging ports, high resolution CFI60 optics, and ... imaging workstation. In addition, its super-nanoprecision z-axis ... is perfect for precise imaging in 3D. ...
Medicine Products: