Navigation Links
Stroke victims have new hope with activated protein C

A new study by researchers from the University of Rochester, New York suggests that the activated protein C (APC), a protein with anti-inflammatory and anti-coagulant properties,which until now is being used to treat septic infections, may also help reduce the damage caused by stroke. Researchers who conducted the study on mice found that APC could protect brain cells from the secondary damage associated with ischemic stroke by preventing apoptosis, a form of programmed cell death. The study has shown// that APC reduced apoptosis by 65 per cent and neurological deficits by 91 per cent when given to mice following a stroke. Currently, only tissue plasminogen activator is useful for the 80 per cent of strokes that involve a blood clot, but can damage cells if given after the first few hours.

Further analysis by this team of researchers has shown that APC blocks p53, a molecule that drives cells towards apoptosis following stroke. APC works through two cellular receptors, called endothelial protein C receptor and protease-activated receptor 1, to reduce the level of p53 in damaged cells by 75 per cent. APC also increases anti-apoptotic signals that instruct cells to survive. Researchers concluded that the compound which is working in a completely unexpected way could spur further research to help develop treatments that reduce the lifelong disability often associated with stroke.


'"/>




Page: 1

Related medicine news :

1. Amphetamines Help Recovery of Stroke Patients
2. Cough Syrup Ingredient Linked to Stroke
3. Estrogen Does Not Prevent Recurrent Strokes
4. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
5. Triglycerides Linked To Stroke Risk
6. Strokes increased during squatting
7. Drug Combinations May Boost Stroke Risk
8. Stroke and Dementia - a ghastly association
9. Stroke risk might be linked to antibody
10. Stroke Risk and Fish :A factual interconnection
11. Fewer teeth & Increased Ischemic Stroke risk
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: