Navigation Links
Stroke victims have new hope with activated protein C

A new study by researchers from the University of Rochester, New York suggests that the activated protein C (APC), a protein with anti-inflammatory and anti-coagulant properties,which until now is being used to treat septic infections, may also help reduce the damage caused by stroke. Researchers who conducted the study on mice found that APC could protect brain cells from the secondary damage associated with ischemic stroke by preventing apoptosis, a form of programmed cell death. The study has shown// that APC reduced apoptosis by 65 per cent and neurological deficits by 91 per cent when given to mice following a stroke. Currently, only tissue plasminogen activator is useful for the 80 per cent of strokes that involve a blood clot, but can damage cells if given after the first few hours.

Further analysis by this team of researchers has shown that APC blocks p53, a molecule that drives cells towards apoptosis following stroke. APC works through two cellular receptors, called endothelial protein C receptor and protease-activated receptor 1, to reduce the level of p53 in damaged cells by 75 per cent. APC also increases anti-apoptotic signals that instruct cells to survive. Researchers concluded that the compound which is working in a completely unexpected way could spur further research to help develop treatments that reduce the lifelong disability often associated with stroke.


'"/>




Page: 1

Related medicine news :

1. Amphetamines Help Recovery of Stroke Patients
2. Cough Syrup Ingredient Linked to Stroke
3. Estrogen Does Not Prevent Recurrent Strokes
4. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
5. Triglycerides Linked To Stroke Risk
6. Strokes increased during squatting
7. Drug Combinations May Boost Stroke Risk
8. Stroke and Dementia - a ghastly association
9. Stroke risk might be linked to antibody
10. Stroke Risk and Fish :A factual interconnection
11. Fewer teeth & Increased Ischemic Stroke risk
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension ... that it will receive two significant new grants to support its work to ... its 25th anniversary by recognizing patients, medical professionals and scientists for their work ...
(Date:6/24/2016)... ... , ... Comfort Keepers® of San Diego, CA is excited to announce they ... to drive cancer patients to and from their cancer treatments. Comfort Keepers provides ... life and ongoing independence. Getting to and from medical treatments is one of ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Ill. and INDIANAPOLIS , ... students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is ... 2016 scholarship winners, announced today online at www.diabetesscholars.org ... let type 1 diabetes stand in the way of ... has supported the Foundation,s scholarship program since 2012, and ...
(Date:6/23/2016)... June 23, 2016  Guerbet announced today that it ... Supplier Horizon Award . One of 12 ... recognized for its support of Premier members through exceptional ... excellence, and commitment to lower costs. ... recognition of our outstanding customer service from Premier," says ...
(Date:6/23/2016)... June 23, 2016  Experian Health, the ... transforming the patient payment and care experience, ... new products and services that will enhance ... cycle offerings. These award-winning solutions will enable ... remain compliant in an ever-changing environment and ...
Breaking Medicine Technology: