Navigation Links
Stressed Mice may Hold Clue to How Fat is Stored: Study

Ever dream of shifting around body fat to flatten your tummy and boost your bust all without surgery? Or maybe blocking that ample fat? According to an international study published Sunday, the fantasy could become reality.

The study, published online in Nature Medicine, could "revolutionise human cosmetic and reconstructive surgery and treatment of diseases associated with human obesity," the Georgetown University Medical Center in Washington, which participated in the research, said in a statement.

In the study, American, Australian and Slovak researchers describe a mechanism they found by which stress activates weight gain in mice. By manipulating this pathway, they said they were in fact able to selectively add fat to their test subjects.

"We couldn't believe such fat remodeling was possible, but the numerous different experiments conducted over four years demonstrated that it is, at least in mice," Zofia Zukowska, the study's senior author and a Georgetown professor, said in the statement.

"We are hopeful that these findings might eventually lead to control of metabolic syndrome.... Decreasing fat in the abdomen of the mice we studied reduced the fat in their liver and skeletal muscles, and also helped control insulin resistance, glucose intolerance, blood pressure and inflammation," she added.

The researchers tested how stressed and unstressed mice on different diets accumulated and stored fat, discovering that stressed mice eating high calorie food gained twice as much fat as unstressed mice eating the same meals.

"We have known for over a decade that there is a connection between chronic stress and obesity," said Professor Herbert Herzog at the Garvan Institute of Medical Research in Sydney, which participated in the study.

"Now we have identified the exact pathway, or chain of molecular events, that links chronic stress with obesity," he said.

Th e researchers found that both neurotransmitters (neuropeptide Y, or NPY) and the receptors (neuropeptide Y2 receptor, or Y2R) are activated during stress, leading to obesity and metabolic syndrome in mice on fatty diets.

By injecting Y2R blockers into abdominal fat, however, they managed to ward off both obesity and metabolic disorders.

With more than 300 million people worldwide suffering from obesity and 800 million more considered overweight, according to international estimates, ever more scientists are joining the search for that miracle molecule that will slim us all down.

While most pharmaceutical solutions have so far focused "with moderate success" on appetite suppressants, Herzog said that "our hope is that in the near future pharmaceutical companies, using the results of our research, will develop antagonists against the Y2 receptor that will bring about a reduction in fat cells."

Georgetown professor Stephen Baker, who co-authored the study, meanwhile pointed out that the ability to add fat selectively would be useful for cosmetic restructuring, like facial reconstruction, breast, buttock and lip enhancements.

"This is the first well-described mechanism found that can effectively eliminate fat without using surgery," he said, adding that "a safe, effective, non-surgical means to eliminate undesirable body fat would be of great benefit to our patients."


'"/>




Related medicine news :

1. Students Involved In Bullying And Victims Were Equally Stressed
2. Stress Statistics May Leave You Stressed Out
3. Stressed Pregnant Working Mothers Put Their Unborn Child’s Life in Dange
4. Educationists Stressed the Need for Common School System for the Country
5. Stressed African American Youth At Greater Risk for Kidney Disease
6. US Army to Recruit More Psychiatrists to Counsel Stressed Out Soldiers
7. Kalam Stressed the Need for Stem Cell Research to Cure Neuro Disorder
8. Tomato Sauce reduces Cancer Risk- Study
9. Study on obesity and heart failure
10. National Lung Study in the process
11. Study casts doubt on keyboard ills
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... ... May 24, 2017 , ... Rob Lowe is a sought after ... Public Television. “Informed” brings the public important topics from all aspects of life, and ... feet and issues surrounding feet and ankles. , Podiatry is essential to people’s overall ...
(Date:5/24/2017)... , ... May 24, 2017 , ... Technique, technique, technique ... injury when either lifting weights for strength training and exercise or simply lifting heavy ... . , “Body position is everything,” Dr. Chang says. “Improper technique in lifting anything ...
(Date:5/23/2017)... ... ... Axiad IDS , a leading provider of trusted identities for enterprise, ... a “Top 25 Cybersecurity Companies 2017.” Axiad IDS received this honor in ... address potential cybersecurity threats before they happen. The annual list of top ...
(Date:5/23/2017)... ... 2017 , ... Cambridge, MA, May 23, 2017—Total costs per ... a Workers Compensation Research Institute (WCRI) study, a contrast from the increases of ... Benchmarks, 17th Edition looks at indemnity and medical payments for workers’ compensation ...
(Date:5/23/2017)... ... May 23, 2017 , ... The National Council ... pleased to announce the organization’s Certified Strength Coach credential has earned accreditation from ... (CSC) program validates the competency of qualified candidates for jobs in the Strength ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... WAYNE, Pa. , May 4, 2017 /PRNewswire/ ... made from thermoplastics and other highly-engineered materials, is ... Microextrusion tubing has been developed in recent ... neurovascular interventional therapies and surgical applications. More expensive ... used to produce microextrusion tubing due to their ...
(Date:5/3/2017)... May 3, 2017  Kalorama Information notes that ... percent next year and this is projected to ... stem cell (HSCT) or bone marrow transplants require ... are well-suited for this task. This according to ... Kalorama Information. The various PCR-based methodologies, Sanger sequencing ...
(Date:5/2/2017)... YORK and LONDON , ... of market intelligence, MarketResearch.com is pleased to announce a ... AB that allows for the marketing and distribution ... analyses through the MarketResearch.com website. The new ... to complete product descriptions and tables of contents from ...
Breaking Medicine Technology: