Navigation Links
Stressed Mice may Hold Clue to How Fat is Stored: Study

Ever dream of shifting around body fat to flatten your tummy and boost your bust all without surgery? Or maybe blocking that ample fat? According to an international study published Sunday, the fantasy could become reality.

The study, published online in Nature Medicine, could "revolutionise human cosmetic and reconstructive surgery and treatment of diseases associated with human obesity," the Georgetown University Medical Center in Washington, which participated in the research, said in a statement.

In the study, American, Australian and Slovak researchers describe a mechanism they found by which stress activates weight gain in mice. By manipulating this pathway, they said they were in fact able to selectively add fat to their test subjects.

"We couldn't believe such fat remodeling was possible, but the numerous different experiments conducted over four years demonstrated that it is, at least in mice," Zofia Zukowska, the study's senior author and a Georgetown professor, said in the statement.

"We are hopeful that these findings might eventually lead to control of metabolic syndrome.... Decreasing fat in the abdomen of the mice we studied reduced the fat in their liver and skeletal muscles, and also helped control insulin resistance, glucose intolerance, blood pressure and inflammation," she added.

The researchers tested how stressed and unstressed mice on different diets accumulated and stored fat, discovering that stressed mice eating high calorie food gained twice as much fat as unstressed mice eating the same meals.

"We have known for over a decade that there is a connection between chronic stress and obesity," said Professor Herbert Herzog at the Garvan Institute of Medical Research in Sydney, which participated in the study.

"Now we have identified the exact pathway, or chain of molecular events, that links chronic stress with obesity," he said.

Th e researchers found that both neurotransmitters (neuropeptide Y, or NPY) and the receptors (neuropeptide Y2 receptor, or Y2R) are activated during stress, leading to obesity and metabolic syndrome in mice on fatty diets.

By injecting Y2R blockers into abdominal fat, however, they managed to ward off both obesity and metabolic disorders.

With more than 300 million people worldwide suffering from obesity and 800 million more considered overweight, according to international estimates, ever more scientists are joining the search for that miracle molecule that will slim us all down.

While most pharmaceutical solutions have so far focused "with moderate success" on appetite suppressants, Herzog said that "our hope is that in the near future pharmaceutical companies, using the results of our research, will develop antagonists against the Y2 receptor that will bring about a reduction in fat cells."

Georgetown professor Stephen Baker, who co-authored the study, meanwhile pointed out that the ability to add fat selectively would be useful for cosmetic restructuring, like facial reconstruction, breast, buttock and lip enhancements.

"This is the first well-described mechanism found that can effectively eliminate fat without using surgery," he said, adding that "a safe, effective, non-surgical means to eliminate undesirable body fat would be of great benefit to our patients."


'"/>




Related medicine news :

1. Students Involved In Bullying And Victims Were Equally Stressed
2. Stress Statistics May Leave You Stressed Out
3. Stressed Pregnant Working Mothers Put Their Unborn Child’s Life in Dange
4. Educationists Stressed the Need for Common School System for the Country
5. Stressed African American Youth At Greater Risk for Kidney Disease
6. US Army to Recruit More Psychiatrists to Counsel Stressed Out Soldiers
7. Kalam Stressed the Need for Stem Cell Research to Cure Neuro Disorder
8. Tomato Sauce reduces Cancer Risk- Study
9. Study on obesity and heart failure
10. National Lung Study in the process
11. Study casts doubt on keyboard ills
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... ... 2017 , ... The world-class designers of Happy Gadget Alert ... lifesaving device for the everyday use of parents worldwide. It is a lightweight, ... a child’s vital signs, and detect unusual symptoms or physical patterns. This innovative ...
(Date:4/24/2017)... ... April 24, 2017 , ... Salus Telehealth, Inc. ... company’s VideoMedicine mobile platform has launched Quick Care, a new service offering on-demand ... Care provides patients with the option to request and begin a consultation with ...
(Date:4/24/2017)... ... April 24, 2017 , ... According to the ... now claim the lives of 62 Americans each day.(1) Yet since 2011, the ... distributors, pharmacies and prescribers by more than half.(2) Novus Medical Detox Center ...
(Date:4/24/2017)... ... 24, 2017 , ... MAP Health Management announced today a ... with addiction who are served by MAP’s patient engagement ecosystem. Lief Therapeutics is ... heart and breath rates to identify anxiety levels and can provide biofeedback exercises ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... ... health of individuals with HIV because it is not known to have significant ... have favorable effects to both lower cholesterol levels and dampen inflammation in the ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017 Research and Markets has ... Market Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, ... their offering. ... pharmacogenomics market was valued at US$ 7,167.6 Mn in 2015, ... expanding at a CAGR of 5.6% from 2016 to 2024. ...
(Date:4/20/2017)... , April 20, 2017 Research and ... Pharmaceutical Contract Manufacturing Services Market Analysis By Service (Manufacturing, Research), ... Forecasts, 2014 - 2025" report to their offering. ... The Latin American pharmaceutical ... billion by 2025 Low drug registration cost in ...
(Date:4/19/2017)... , April 19, 2017 The Mobile X-Ray product ... a healthy CAGR during the forecast period Mobile ... the global digital mobile X-Ray devices market, which is estimated ... 2017, expanding at a CAGR of 7% over the forecast ... opportunity of more than US$ 100 Mn in 2017 over ...
Breaking Medicine Technology: