Navigation Links
Steroid Drugs to Preterm Delivery Mothers may Cause Risk

Researchers in this weeks BMJ question whether giving repeated courses of steroid drugs to mothers at risk of preterm delivery is based on sound evidence .

Babies born before 32 weeks of pregnancy often have neonatal lung disease, a major cause of illness and death - the earlier the birth, the greater the risk.

In the 1990s, the benefit of giving antenatal corticosteroids to prevent lung disease in preterm babies was established. Several analyses concluded that steroids were most effective when given within a week of delivery and this led to repeated treatment for women who did not deliver within this time frame. Many mothers received multiple courses of corticosteroids during the 1990s and early 2000s.

But now two researchers warn that methodological problems in these analyses mean that this conclusion may be wrong and the practice of repeating courses was not based on any good evidence. We do not yet know whether this practice was beneficial or harmful.

The main problem, they say, is that the analyses of subgroups of people in the research studies were not done correctly and may have been misleading.

Several trials are now underway to determine the efficacy and safety of repeated courses of steroids. Results so far have shown no conclusive evidence of short-term benefit but long-term follow-up is needed to fully understand the benefits and risks, say the authors.

Until then, they suggest that reanalysis of the data from the original trials may help to clarify whether effectiveness declines with time to delivery, and if so, over what timescale this occurs.

But they warn that these new trials should avoid making the same errors in subgroup analyses or we risk repeating the errors made in the conclusions of the original antenatal steroid trials.


'"/>




Page: 1

Related medicine news :

1. Inhaled Steroids Safe & Effective for Children with Asthma
2. Mislabeled Body-building Steroid Supplements
3. Steroid Treatment for Wheezing Questioned
4. Steroid-Free Liver Transplants
5. The Use Of Steroids for Dizziness Questioned
6. Biofeedback Found To Reduce Steroid Dependence In Asthmatics
7. Steroid Treatment after head injury may be fatal
8. The Link Between High-dose Steroid Use And Heart Disease Questioned
9. The Use Of Oral Steroids For Muscular Dystrophy Questioned
10. No Steroids for Traumatic Brain Injury
11. Steroids Effective For Treating Carpel Tunnel Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/27/2017)... (PRWEB) , ... April 27, 2017 , ... Are you ... tragic spike in water-related accidents and drownings during the summer. While most of us ... that these situations occur every day. Very few people are taking the time to ...
(Date:4/26/2017)... ... 26, 2017 , ... Intalere, the healthcare industry leader in ... Plans for MACRA,” highlighting the impact of the Medicare Access and CHIP ... and other clinicians are reimbursed for the care they deliver in Medicare. , ...
(Date:4/26/2017)... ... April 26, 2017 , ... CareSet Labs today is ... as measured in Part D Medicare data. The dataset, called PaPR (Providers and ... e-prescribing, faxes or paper. The PaPR (pronounced "paper") data set aggregates this ...
(Date:4/26/2017)... ... 2017 , ... The National Business Research Institute (NBRI) is ... Emergency Medical Technicians and welcomes this organization to the NBRI Circle of ... Ph.D. , CEO & Organizational Psychologist at NBRI. “This award is a result ...
(Date:4/26/2017)... ... April 26, 2017 , ... RawTrition now brings you BioEnergy which is a ... SUPERFOODS! , RawTrition is taking nutrients to the next level! The ... recognizes its raw form (unlike the synthetically made options that are on the market). ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017 Global ... This report on the prostate cancer therapeutics market ... global market. Increasing prevalence of prostate cancer, launch ... in the development of new drugs & therapeutic ... cancer drug due to lesser side effects are ...
(Date:4/19/2017)... , April 19, 2017  New research provides evidence that ... Parkinson,s, according to a study released today that will be ... Meeting in Boston , April 22 ... the treatment of Parkinson,s disease, the oral drug levodopa has ... and longevity. But as the disease progresses, the effects of ...
(Date:4/18/2017)... April 18, 2017 Viverae ® , a ... the integration of IBM ® Watson Campaign Automation, ... targeted communications for a personalized experience. Through digital engagement, ... their health in real time. The enhanced experience drives ... to members, wherever they are in their journey to ...
Breaking Medicine Technology: