Navigation Links
Stem cells offer hope for muscular dystrophy

Italian researchers said on Thursday they were combining two new and experimental therapies -- using stem cells and gene therapy -- to try to treat muscular dystrophy. Their early work has shown some success in mice but they warned any real progress is years away.
Writing in the journal Science, the team lead by Dr. Giulio Cossu of the Stem Cell Research Institute in Milan and the University of Rome said certain stem cells //had been coaxed into strengthening the muscles of mice with muscular dystrophy.

There are nine forms of muscular dystrophy, which affect 300,000 people in the United States alone. This group of genetic diseases is marked by progressive weakness and degeneration of the muscles that control movement, as well as, sometimes, the heart and other organs. There is no treatment or cure.

Cossu and colleagues worked with cells called mesoangioblasts, a type of stem cell. Stem cells are master cells that can produce a whole range of cells and tissues. Mesoangioblasts are called "adult" stem cells although this particular kind has so far been found only in fetuses.

The researchers injected mesoangioblasts into the arteries of mice genetically engineered to lack the alpha sarcoglycan gene -- in effect giving the mice a form of MD. These mesoangioblasts turned up downstream. The team then genetically engineered the stem cells, putting in healthy versions of alpha sarcoglycan gene, and injected these into the mice. Three months later, they found healthy alpha sarcoglycan proteins in the muscles of the treated mice. "The muscle cells of a dystrophied mouse are extremely weak, but a cured mouse recovered almost entirely all its strength," said Roberto Bottinelli from the University of Pavia, who worked on the study.

The experiment proves a theory but some real-world stumbling blocks remain. For instance, the approach would work best if a patient's own mesoangioblasts were used, but these cells have so
'"/>




Page: 1 2

Related medicine news :

1. Action of nerve cells
2. Therapy for stopping the spread of cancer cells
3. Hydroxyurea derivatives kill colon cancer cells
4. Creating brain cells from bone marrow
5. A Chinese herb kills cancer cells
6. Immune cells halt round in space
7. Transforming stem cells to lung cells
8. Changing stem cells to liver cells
9. Enzyme stimulates growth of adult stem cells
10. Stem cells aid to cure brain cancer
11. Brain cells protected by new compounds
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stem cells offer hope for muscular dystrophy

(Date:7/22/2014)... on Lung Cancer (LALCA 2014) will be held August ... Cancer is still the leading cause of death not ... success of the previous conferences in Chile, Mexico, Argentina ... science and advances in the treatment and prevention of ... in particular. , With tobacco being the leading cause ...
(Date:7/22/2014)... Ticket Down is a reliable source for cheap ... Landover, MD. There has never been a better time in ... the success of the American national soccer team at the 2014 ... way that fans of the world’s sport will be able to ... International Champions Cup. The tournament will kick off on July 24 ...
(Date:7/22/2014)... 22, 2014 The Entertainment Industries Council, ... resources, educational tools and recognition activities for thousands of ... prevention, treatment and recovery. On July 24, 2014, at ... some of these resources with a special mention of ... and treatment website at the end of the show. ...
(Date:7/22/2014)... London, UK (PRWEB) July 22, 2014 ... considerably over the past few years, owing to novel ... performed with BoNTs in the aging societies where physical ... is led by one player, current competitors, new companies ... for biosimilars. As biosimilar BoNTs will put the price ...
(Date:7/22/2014)... HealthDay Reporter TUESDAY, July 22, 2014 ... procedure known as morcellation carries a risk of spreading undetected ... clearly. Twenty-seven of every 10,000 women who had the ... procedure, researchers found, with the odds being highest for patients ... with morcellation use a power cutter to slice uterine tissue ...
Breaking Medicine News(10 mins):Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 2Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 3Health News:ABC’s BLACK BOX Spotlights Mental Health and Available Resources in Upcoming Episode 2Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 2Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 3Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 4Health News:Technique Used in Some Hysterectomies May Help Spread Cancer: Study 2Health News:Technique Used in Some Hysterectomies May Help Spread Cancer: Study 3
... February issue of PNAS that understanding and treating cholesterol-related ... discovery of a receptor in the cells of mice ... during a study of cerebrotendinous xanthomatosis (CTX), a rare ... They said that Pregnane X receptor (PXR)// is present ...
... curvature of the spine diagnosed after the age ten, ... to earlier belief that the condition increases mortality rates ... related to the curvature. Researchers from the University of ... with LIS appear to experience only little physical// impairment ...
... to be launched by researchers from the UK and Netherlands ... with cancer. The research will be led by Dr. Julian ... Dr. René Bernards of the Netherlands Cancer Institute. This research ... and will have scientists looking at nearly 10,000 genes, inactivating ...
... journal, Cancer Cell reported that scientists have discovered why some ... others. Researchers have found that high levels of a specific ... drugs such as Taxol, which are used to treat a ... the// researchers focused on a molecule called AURORA-A which is ...
... has shown that those who smoke face the highest ... However, researchers added that more studies are needed before ... of cross-sectional data obtained from the US National Household ... from 1994 to 1996) was conducted. A total// of ...
... from the Department of Human Services at the University ... elevated levels of abdominal visceral fat are associated with ... was also found to be a primary determinant in ... investigators assessed// plasma lipids and lipoproteins and their relationships ...
Cached Medicine News:Health News:Cancer gene mystery to be cracked! 2
(Date:7/22/2014)...  Decision Resources Group finds that the market for interventional ... remain relatively stagnant at a value of around $80 million ... intervention (PCI) volumes are growing faster in Canada ... the United States and Europe ... increase in penetration of PCI procedures relative to coronary artery ...
(Date:7/22/2014)... According to a new ... (Technology Types - Near infrared (NIR) spectroscopy, Raman spectroscopy and ... Size, Share, Growth, Trends and Forecast, 2013 - 2019," the ... is expected to grow at a CAGR of 7.4% from ... was the largest contributor to global process spectroscopy market ...
(Date:7/22/2014)... , July 22, 2014  Eyeon Therapeutics has received ... treatment based on a charged hydrophilic polymer developed at ... has been shown to be safe and effective in ... MD, CEO states, "This first set of claims around ... way to moving this technology into the commercial phase.  ...
Breaking Medicine Technology:The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 2Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 4Particle Sciences and Eyeon Therapeutics Receive Patent on Novel Dry Eye Technology 2
... 12, 2011 Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ... on August 29, 2011, as Vice President, Finance and Chief ... Arena for over 13 years before departing in March to ... a valuable leader who has been a key contributor to ...
... 2011 5 modules - 2 weeks - ... to announce that the Stability Testing Online Training Course is proving ... ,The secret behind the Stability testing Online Training Course ... is its user-friendly format which allows flexible and interactive high standard, ...
Cached Medicine Technology:Robert Hoffman to Rejoin Arena Pharmaceuticals as Vice President, Finance and Chief Financial Officer 2Robert Hoffman to Rejoin Arena Pharmaceuticals as Vice President, Finance and Chief Financial Officer 3Stability Testing Course is Taking the Online Training Format by Storm! 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: