Navigation Links
Stem Cells Speed Growth of Healthy Liver Tissue

OAK BROOK, Ill.—For the first time, researchers have used adult bone marrow stem cells to regenerate healthy human liver tissue,// according to a study published in the April issue of the journal Radiology.

When large, fast-growing cancers invade the liver, some patients are unable to undergo surgery, because removing the cancerous tissue would leave too little liver to support the body.

Researchers at Heinrich-Heine-University in Düsseldorf, Germany, used adult bone marrow stem cells to help quickly regenerate healthy liver tissue, enabling patients to eventually undergo a surgical resection.

“Our study suggests that liver stem cells harvested from the patient’s own bone marrow can further augment and accelerate the liver’s natural capacity to regenerate itself,” said Günther Fürst, M.D., co-author and professor of radiology.

In the study, researchers compared the results of portal vein embolization (PVE), a technique currently used to help regenerate liver tissue, to a combination of PVE and an injection of bone marrow stem cells into the liver.

PVE blocks blood flow to the diseased portion of the liver and diverts blood to the organ’s healthy tissue, promoting liver growth. Bone marrow stem cells extracted from the patient’s hip bone and injected into the liver also help the liver regenerate.

The study included 13 patients with large central liver malignancies who were unable to undergo surgery because resection would leave less than 25 percent of their total liver volume.

Six of the patients underwent both PVE and injection of bone marrow stem cells. Seven patients underwent only PVE. Computed tomography (CT) scans were performed before and up to five weeks after PVE to determine the degree of liver growth.

Patients who received the combination of PVE and stem cell injection had double the liver growth rate and gain in liver volume, compared with those who underw ent PVE alone. As a result, the patients who received the combined treatment were able to undergo surgery an average of 18 days sooner than patients who received PVE only.

“Our research demonstrates that stem cells are a powerful adjunct to PVE for patients undergoing surgical resection,” said Jan Schulte am Esch, M.D., co-author and surgery staff member. “Based on our results, we also believe that adult stem cell administration may be a promising therapy for regenerating livers damaged by other chronic and acute diseases.”

The researchers are currently embarking on a randomized controlled trial of the therapy.


Related medicine news :

1. Blood Cells Capable of Regenerating Liver
2. White Cells Count Can Predict Heart Attack Death Risk
3. Gene Therapy Destroys Pancreatic Cancer Cells
4. Stem Cells Have Few Mutations
5. Heart may pull Cells from Body to Self-repair
6. Cells critical for asthma development found
7. Vitamin D Wipes out Cancer Cells
8. Bone Marrow Cells Help Heart Attack Patients
9. Islet Cells May Lead to Diabetes CureChildren
10. Stem Cells Found To Offer Promise For Hair Growth
11. Bone Marrow Cells Could Yield A New Lease of Life
Post Your Comments:

(Date:11/30/2015)... ... November 30, 2015 , ... RoamRight, a leading provider of ... Public Television’s Travel With Kids to promote family vacations around the world. ... they explore international destinations and educate families about the people and places of the ...
(Date:11/30/2015)... ... 2015 , ... A novel class of antimicrobials that inhibits ... fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial pathogens, according ... analogs that target the functions of SecA, a central part of the general ...
(Date:11/30/2015)... ... November 30, 2015 , ... At Grand Dental PC, their priority is ... When you have dental problems, you need to turn to a dentist who listens ... treat your needs, a friendly dentist who counsels you on the best ways to ...
(Date:11/30/2015)... ... November 30, 2015 , ... Using a combination of two ... American children and adults, according to a new study by researchers at the School ... in Children and Adults: Using Combinations of Blood Glucose Tests ,” published in Frontiers ...
(Date:11/30/2015)... ... November 30, 2015 , ... Newly ... out of Glen Ridge, NJ. He has both advanced training and considerable ... He is also an expert in cosmetic dentistry. He is an active ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... CHICAGO , Dec. 1, 2015 Researchers ... that measures body part thickness and checks for motion, ... to a feasibility study presented today at the annual ... America (RSNA). Steven Don , ... Radiology, Washington University School of Medicine in ...
(Date:11/30/2015)... Express Scripts (NASDAQ: ESRX ) today announced it will ... access to a low-cost alternative to Daraprim (pyrimethamine) , ... recently priced out of reach for people with HIV, pregnant ... --> --> Imprimis is offering a compounded ... acid) for $1 per capsule for people whose pharmacy benefit is ...
(Date:11/30/2015)... décembre 2015 MEDTEC Japon ... conférence d,Asie portant sur la conception ... manufacturière, se tiendra à ... 22 avril 2016. ... Photo - Logo ...
Breaking Medicine Technology: