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Stem Cells Research in Parkinsons Disease

disease. Its the first step in translating that research, he said.

We hear about new sources of stem cells monthly, but how we take those cells and treat disease is going to be a significant amount of translational work. This is one of the first studies that starts that process looking at primates before going into people with Parkinsons disease.

While the transplanted cells appeared not to form tumors following transplant, Dr. Sanberg said the translational research in primates raises questions that need to be addressed before moving to human trials, including determining the most effective cell dosing and brain sites to target.

Pending further preclinical studies, he writes in the commentary, the results so far from the current study are supportive for developing a safe and effective stem cell treatment for Parkinsons disease.

Dr. Sanbergs commentary and the study it highlights will also be published in the magazine edition of PNAS, a prestigious publication with a global audience. PNAS has been a resource for multidisciplinary research since 1914. Its online edition, where Dr. Sanbergs commentary appears this week, receives nearly 6 million e-visitor hits per month.

Content includes research reports, commentaries, reviews, perspectives, colloquium papers, and actions of the Academy. Coverage in PNAS spans the biological, physical, and social sciences.


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