Navigation Links
Stem Cell Treatment may Prolong Lives of Children With Brittle Bone Disease

Researchers at Imperial College London have found that injections of stem cells during the gestation period may help prolong the lives of children with brittle bone disease , osteogenesis imperfecta (OI).

The genetic defect, detected in human foetuses by DNA testing or ultrasound, disrupts collagen production, leading to weak bones and stunted growth. Those with the condition suffer fractures while in the womb, and rarely survive beyond early adulthood.

Led by Nicholas Fisk of the college, the researchers studied mouse models of human type III osteogenesis imperfecta. They injected human foetal mesenchymal stem cells through the wall of the uterus into 14-day mouse foetuses.

It was found that at the age of 3 months, mice treated with stem cells had suffered just one-third of the long-bone fractures, as compared to their untreated counterparts. The experimental mice also had stronger bones and longer leg bones than the control subjects.

A report published in New Scientist magazine says that the treatment has already been tried in the US on three children with OI whilst still in the womb, with promising early results seen after the babies were born.

Fisk believes that though drugs exist to treat the disease, stem cell transplants may offer extra benefits.

The researcher, who presented the study at the annual meeting of the International Society for Stem Cell Research in Cairns, Australia, stresses that need for offering the treatment on a case-by-case basis.

However, other experts are of the opinion that clinical trials must be conducted before the treatment is offered to the public.


'"/>




Page: 1

Related medicine news :

1. Advances in Treatment of Cataracts
2. Recommendations for Treatment of Blood Pressue
3. Treatment for Menieres disease
4. Treatment for pre-menstrual syndrome is ineffective
5. Better Treatment for obesity
6. Gene Treatment for Heart Disease
7. More People Seeking Treatment for Depression
8. Focused Treatment For Childhood Cancer
9. Inadequate Drug Treatment For Youth
10. FDA Approves New surgery Treatment for Farsightedness
11. Treatment of antibiotics ineffectual in bronchitis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
Breaking Medicine Technology: