Navigation Links
Stem Cell Therapy For Heart Attack Found To Be Ineffective

A recent study has now established that stem cell therapy for heart attack may not be as effective as it is claimed to be, when tested under rigorous conditions//. German researchers have stated that bone marrow transplantation may not improve cardiac function following heart attack.

Over the past few years, very few topics have had the potential to attract the attention of public and scientists alike. One such is the controversial area of stem cell research and therapy. Day by the day, a number of studies are being published, highlighting the promise of stem cell therapy in the treatment of neurodegenerative disorders, hematological malignancies, injury, and many others.

Evidence is accumulating on the importance of stem cells in regeneration of cardiac tissue. It is even believed to lead to the development of new blood vessels after a heart attack. Mobilization of bone marrow stem cells can be achieved through stimulation of a growth factor protein, called granulocyte colony-stimulating factor (G-CSF).

The researchers conducted a randomized, double blind, placebo-controlled study (REVIVAL-2) to assess effect of G-CSF treatment in a large study population (114 patients) following a heart attack. All the study participants were diagnosed to have a ST-segment elevation, characteristic of acute myocardial infarction.

The patients had undergone angioplasty and other similar percutaneous coronary intervention procedures for opening up a narrowed coronary artery. They were assigned to receive either G-CSF or a placebo for 5 days following treatment. A daily dose of 10 μg/kg of the growth factor was given in the form of an injection.

Although G-CSF protein produced a satisfactory mobilization of bone marrow stem cells, the size of the infarct or the left ventricular function remained unaltered following a heart attack. Furthermore, no increased risk of restenois or other adverse cardiac events could be documented with G-CSF treatment.

The results of this study can be found in the latest issue of JAMA. This study also highlights need for caution about the direct application of experimental results to clinical practice, without careful analysis, that may lead to complications, not foreseen at the moment.


Related medicine news :

1. Cancer Doctors Okays Controversial Prostate Therapy
2. Consensus on "Combination Therapy" for Breast Cancer
3. Gene Therapy shows promise in treating Hemophilia
4. "Make AIDS Therapy affordable" - Physicians demand
5. Hormone replacement Therapy a headache
6. Simple Therapy
7. Therapy for stopping the spread of cancer cells
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Letrozole Beats Tamoxifen in Breast Cancer Therapy
10. Garlic Supplements Impede HIV Therapy
11. Gene Therapy For Cystic Fibrosis
Post Your Comments:

(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... ... June 27, 2016 , ... recently awarded their ... Eyeglasses . , Millions of individuals in the United States and Canada wear eyeglasses. ... way to both correct vision and make a fashion statement. Even celebrities use glasses ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women ... diagnosed with endometriosis. These women need a treatment plan to not only alleviate ... that can help for preservation of fertility and ultimately achieving a pregnancy. The ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
(Date:6/23/2016)... Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new ... affiliate in Latin America . ... ... ... ...
Breaking Medicine Technology: