Navigation Links
Stem Cell Therapy For Heart Attack Found To Be Ineffective

A recent study has now established that stem cell therapy for heart attack may not be as effective as it is claimed to be, when tested under rigorous conditions//. German researchers have stated that bone marrow transplantation may not improve cardiac function following heart attack.

Over the past few years, very few topics have had the potential to attract the attention of public and scientists alike. One such is the controversial area of stem cell research and therapy. Day by the day, a number of studies are being published, highlighting the promise of stem cell therapy in the treatment of neurodegenerative disorders, hematological malignancies, injury, and many others.

Evidence is accumulating on the importance of stem cells in regeneration of cardiac tissue. It is even believed to lead to the development of new blood vessels after a heart attack. Mobilization of bone marrow stem cells can be achieved through stimulation of a growth factor protein, called granulocyte colony-stimulating factor (G-CSF).

The researchers conducted a randomized, double blind, placebo-controlled study (REVIVAL-2) to assess effect of G-CSF treatment in a large study population (114 patients) following a heart attack. All the study participants were diagnosed to have a ST-segment elevation, characteristic of acute myocardial infarction.

The patients had undergone angioplasty and other similar percutaneous coronary intervention procedures for opening up a narrowed coronary artery. They were assigned to receive either G-CSF or a placebo for 5 days following treatment. A daily dose of 10 μg/kg of the growth factor was given in the form of an injection.

Although G-CSF protein produced a satisfactory mobilization of bone marrow stem cells, the size of the infarct or the left ventricular function remained unaltered following a heart attack. Furthermore, no increased risk of restenois or other adverse cardiac events could be documented with G-CSF treatment.

The results of this study can be found in the latest issue of JAMA. This study also highlights need for caution about the direct application of experimental results to clinical practice, without careful analysis, that may lead to complications, not foreseen at the moment.


'"/>




Related medicine news :

1. Cancer Doctors Okays Controversial Prostate Therapy
2. Consensus on "Combination Therapy" for Breast Cancer
3. Gene Therapy shows promise in treating Hemophilia
4. "Make AIDS Therapy affordable" - Physicians demand
5. Hormone replacement Therapy a headache
6. Simple Therapy
7. Therapy for stopping the spread of cancer cells
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Letrozole Beats Tamoxifen in Breast Cancer Therapy
10. Garlic Supplements Impede HIV Therapy
11. Gene Therapy For Cystic Fibrosis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/4/2016)... , ... December 03, 2016 , ... While James Earl ... serving as host for in a show called "Front Page". One of the forthcoming ... years, breast cancer rates have plummeted in large part due to early detection. Like ...
(Date:12/4/2016)... ... December 04, 2016 , ... Patients who wish to ... advantage of a cosmetic procedure known as Carbon Dioxide (C02) Fractional Laser ... of age spots, fine lines, uneven coloration, wrinkles, scarring, skin laxity or ...
(Date:12/2/2016)... ... December 02, 2016 , ... Lori G. Cohen and ... will speak at the American Conference Institute’s 21st Drug & Medical Device Litigation ... Lead Sponsor of the conference. , Cohen, who chairs the firm’s Pharmaceutical, Medical Device ...
(Date:12/2/2016)... ... December 02, 2016 , ... More than 100 business, civic, ... to attend the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. 9, 2016. This inaugural event, ... and operating support to UNCF-member institutions, including Miles College, Oakwood University, Tuskegee University, ...
(Date:12/2/2016)... ... , ... The annual time frame to change Medicare health and prescription drug ... 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their current plan to ... make changes during this period order for their new policy to go into effect ...
Breaking Medicine News(10 mins):
(Date:12/4/2016)... 2016  Results from the Phase II SUSTAIN study ... reduced the median annual rate of sickle cell-related pain ... 2.98, p=0.010) in patients with or without hydroxyurea therapy ... being featured in the official press briefing at the ... Meeting and presented during the Plenary Scientific Session tomorrow ...
(Date:12/2/2016)... December 2, 2016 - bioLytical lanza el INSTI HIV ... la OMS     Continue Reading ... ... , , bioLytical ... anunciado hoy que está expandiendo el lanzamiento de su INSTI HIV Self Test ...
(Date:12/2/2016)... December 2, 2016 According to the ... Market Study on Automated Endoscope Reprocessors: Single Basin Automated Endoscope ... 8.6% Between 2016 and 2024 " the global automated endoscope reprocessors market was ... to expand at a CAGR of 7.2% during an eight-year ... 1,367.6 Mn by 2024. ...
Breaking Medicine Technology: