Navigation Links
Stem Cell Technology Gives Hope in Spinal Cord Injuries

Recent research using stem-cell technology in rats with spinal-cord injuries has allowed them to walk again within two weeks//. The results of the study show promise for people with traumatic spinal-cord injuries.

According to lead author Dr. Stephen Davies, assistant professor of neurosurgery at Baylor College of Medicine in Houston the rats were given immature immune system support cells called astrocytes and this resulted in a 40-percent rise in nerve-fiber growth at the site of the injury in only eight days.

The results of the research is published in the April 26 in the open-access Journal of Biology. The Christopher Reeve Foundation has partly funded this research.

Stem cell technology for the repair of the central nervous system in humans has been the focus of several studies over many years. This study has shown advances in the use of that technology. Stem cells have the ability to respond to signals in tissue to become cells of that particular type of tissue.

Stem cells can be either of adult or embryonic origin. Adult stem cells are derived from the body’s tissue or organs whereas embryonic stem cells are derived from eggs fertilized in vitro.

Davies explains that the body normally creates scar tissue to prevent infection during any injury including a spinal cord injury. However this mechanism can have disastrous consequences on the spinal cord because scars inhibit nerve-fiber regeneration thereby leading to paralysis and other problems.

And for this very reason transplanting adult stem cells into an injured spinal cord does not encourage nerve growth. .

This led the Davies team to think of signaling cells similar to stem cells known as the glial-restricted precursors, or GRPs, to become a particular type of embryonic astrocyte which was considered to have a remarkable ability of repairing embryonic spinal cord. This in turn was considered for transplantation into adult spinal cord injuries that could inhibit scarring while encouraging nerve growth at the same time.

For this purpose a specific type of astrocyte support cell was generated from the GRPs, discovered by cell biologist Margot Mayer-Proschel of the University of Rochester Medical Center.

It was observed that rats given this specialized astrocyte cell showed less scar tissue and nerve damage in contrast to the control group, which was transplanted with un-cultured cells. Amazingly their locomotion improved to such an extent that they could walk completely normally within two weeks of the treatment

In addition it was observed that the brains of these rats also demonstrated improvement. This was unusual because degeneration of neurons often occurs with spinal cord injuries due to the degeneration of their nerve fibers running down the spinal cord. However with the astrocyte transplant up to 80 percent of nerve degeneration was suppressed.

Dr. Wise Young, a neuroscientist and director of Rutgers University`s W.M. Keck Center for Collaborative Neuroscience has been a pioneer in treating spinal-cord injury. He has organized clinical trials in China, where the influence of umbilical-cord blood stem cells in the central nervous system is planned.

According to Young 'The paper shows very compelling data for moving GRPs to clinical trial as soon as compatible human cells can be obtained.’

However Davies points out that the lack of availability of stem-cell lines in the United States was a big hurdle to be crossed as hundreds of thousands of the GRP cells would be required to act in a person.

Young still remains optimistic that the day was not too far when scientists would be able to make any cell into a stem cell.

In the future Davies hopes to use the new technology to repair central nervous system injuries in people, as well as other neurodegenerative diseases.


'"/>




Related medicine news :

1. New Technology In MRI Scan Help Test Brain Cancer Therapy
2. Emergence Of New Gene Scanning Technology In Disease Research
3. Scientists Develop New Technology To Find About Human Ancestors’ Teet
4. Scientists Consider About New Technology Called Nanotechnology
5. Prostate Cancer Can Be Treated By Application Of LASER Technology
6. Georgia Institute of Technology develops doppler Vein finder
7. Novel Technology For Early Detection of Gastrointestinal Cancer
8. Winter Blues Treated by Breakthrough Lighting Technology
9. Bio-Technology Initiatives to Feed Research On Sorghum Crop
10. Technology Can Help Fight Health Care Costs
11. Technology at its nano best: hand-held lab-on-a-chip for blood tests
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... California (PRWEB) , ... June ... ... pioneer in the patient payment industry today announced its strategic partnership with ... health system workflows. , The two companies’ proven, proprietary technology combine to ...
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, Inc., ... development and manufacturing of collagen and mineral based ... today that Bill Messer has joined ... to further leverage the growing portfolio of oral ... Bill joins the Collagen Matrix executive ...
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
Breaking Medicine Technology: