Navigation Links
Statins Reduce Deaths And Strokes After Carotid Surgery

Statins taken for a week before carotid endarterectomy surgery can reduce the risk of near-term death by 80%, and the risk of early stroke by 65%, say Johns Hopkins researchers//.

Bruce A. Perler, M.D., chief of vascular surgery at the Johns Hopkins Hospital, said, "We found that among patients on statins, the 30-days stroke incidence was only 1.2%, versus 4.5% among patients who were not taking statin drugs, a highly statistically significant difference." "The operative or 30-day mortality among patients on statins was only 03%, as opposed to about 2% among patients who were not taking statin drugs - again, a highly statistically significant difference," Dr. Perler added. Dr. Perler presented the results of a retrospective chart review during a briefing at the AMA's annual science reporters' conference.

Carotid endarterectomy is the most frequently performed peripheral vascular surgery procedure, with about 160,000 to 180,000 operations in the U.S. annually.

Although an endarterectomy can significantly reduce the risk of stroke, "even in the best of hands, 1% to 5% of patients will have a stroke as a result of the surgery," Dr. Perler said. "If we can cut that in half or by two-thirds, that's important."

To evaluate whether the use of statins could reduce the rate of perioperative stroke and death, he and colleagues reviewed the charts of 1,566 patients with a mean age of 72 plus or minus 10, who underwent carotid endarterectomy at their center between 1994 and 2004. Endarterectomy alone was performed for 1,440 patients (92%), and combined endarterectomy and coronary artery bypass graft (CABG) was performed for126.

In all, 657 of the patients (42%) had taken a statin for at least one week before surgery. These patients were significantly more likely than non-statin users to have cardiovascular risk factors, including hypertension, high cholesterol, coronary artery disease, history of smoking, and male gen der. Symptomatic disease was the primary indication for surgery in 660 (42%) of the patients.

The authors found that use of any statin for at least one week before surgery was associated with a significant reduction in perioperative strokes, 1.2% vs. 4.5% (P < .01).

Patients on statins also had significantly fewer transient ischemic attacks, 1.5% vs. 3.6%; P < .01), and a lower incidence of all-cause mortality, 0.3% vs 2.1% (P < .01).

Statin users had shorter median hospital stays (two days, range two to five days) compared with those who didn't take statins (three days, range two to seven days, P < .05).
'"/>




Related medicine news :

1. Statins reduce heart attacks
2. Statins reduce risks for angioplasty patients
3. Statins Found To Be Helpful For Patients With Arthritis
4. Long-Term Benefits Of Statins Questioned
5. Statins Not Effective In Treating Calcific Aortic Stenosis
6. Statins Gives New Hope for Increased Survival Rate of Heart Failure Patients
7. The Effects of Statins Questioned
8. Statins Taken For Reducing Cholesterol Found To Reduce Death Rate Associated With Heart Attack As Well
9. Study Finds No Link Between Statins And Breast Cancer Risk
10. Statins reduces cardiovascular risk but no cancer risk.
11. Statins Prescribed To Those Who Are At a Risk Of Developing A Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/20/2017)... ... February 20, 2017 , ... Today, Illuma Care Connections, a ... during the 2017 Annual HIMSS Conference & Exhibition in Orlando, Florida, ... and integrating eye care into mainstream healthcare delivery is powered by Secure ...
(Date:2/19/2017)... ... 19, 2017 , ... ProBrand Glitch is a set of 30 glitch distortion logo reveals made ... reveal any logo with a glitch reveal in just a few clicks of a mouse. ... animation of each preset. Use these presets to add a uniquely animated logo to any ...
(Date:2/18/2017)... Waltham, Massachusetts (PRWEB) , ... February 17, 2017 ... ... be the leading source of disruptive innovation in the industry, according to the ... Insights Reports are based on surveys of the NEJM Catalyst Insights Council, a ...
(Date:2/18/2017)... CA (PRWEB) , ... February 18, 2017 , ... ... paragraph presets. Use Pixel Film Studios ’ ProParagraph Fashion Volume 2 ... and so many other applications. Users can pick and choose from hand-crafted ...
(Date:2/17/2017)... (PRWEB) , ... February 17, 2017 , ... ... on foundational and sustainable systems change designed to further positively impact the health ... Board of Trustees has long considered it our duty to seriously consider releasing ...
Breaking Medicine News(10 mins):
(Date:2/19/2017)... , Feb. 19, 2017  nThrive™, an ... cycle portfolio and thought leadership at the 2017 ... a category leader award from KLAS. ... discussion focused on how market trends shape the ... particularly a sophisticated, comprehensive Patient Access solution. The ...
(Date:2/19/2017)... SAN FRANCISCO and ORLANDO, Fla. ... (Nasdaq: NKTR ) today announced that positive ... NKTR-214, in patients with renal cell carcinoma (RCC) were ... immuno-stimulatory therapy designed to expand specific cancer-fighting T cells ... tumor micro-environment and increase expression of PD-1 on these ...
(Date:2/18/2017)... -- Research and Markets has announced the addition of the ... ... comprehensive analytics for the US, Canada , ... , Latin America , and Rest of World. Annual ... a six-year historic analysis is provided for these markets. Market data and ...
Breaking Medicine Technology: