Navigation Links
Statins Reduce Deaths And Strokes After Carotid Surgery

Statins taken for a week before carotid endarterectomy surgery can reduce the risk of near-term death by 80%, and the risk of early stroke by 65%, say Johns Hopkins researchers//.

Bruce A. Perler, M.D., chief of vascular surgery at the Johns Hopkins Hospital, said, "We found that among patients on statins, the 30-days stroke incidence was only 1.2%, versus 4.5% among patients who were not taking statin drugs, a highly statistically significant difference." "The operative or 30-day mortality among patients on statins was only 03%, as opposed to about 2% among patients who were not taking statin drugs - again, a highly statistically significant difference," Dr. Perler added. Dr. Perler presented the results of a retrospective chart review during a briefing at the AMA's annual science reporters' conference.

Carotid endarterectomy is the most frequently performed peripheral vascular surgery procedure, with about 160,000 to 180,000 operations in the U.S. annually.

Although an endarterectomy can significantly reduce the risk of stroke, "even in the best of hands, 1% to 5% of patients will have a stroke as a result of the surgery," Dr. Perler said. "If we can cut that in half or by two-thirds, that's important."

To evaluate whether the use of statins could reduce the rate of perioperative stroke and death, he and colleagues reviewed the charts of 1,566 patients with a mean age of 72 plus or minus 10, who underwent carotid endarterectomy at their center between 1994 and 2004. Endarterectomy alone was performed for 1,440 patients (92%), and combined endarterectomy and coronary artery bypass graft (CABG) was performed for126.

In all, 657 of the patients (42%) had taken a statin for at least one week before surgery. These patients were significantly more likely than non-statin users to have cardiovascular risk factors, including hypertension, high cholesterol, coronary artery disease, history of smoking, and male gen der. Symptomatic disease was the primary indication for surgery in 660 (42%) of the patients.

The authors found that use of any statin for at least one week before surgery was associated with a significant reduction in perioperative strokes, 1.2% vs. 4.5% (P < .01).

Patients on statins also had significantly fewer transient ischemic attacks, 1.5% vs. 3.6%; P < .01), and a lower incidence of all-cause mortality, 0.3% vs 2.1% (P < .01).

Statin users had shorter median hospital stays (two days, range two to five days) compared with those who didn't take statins (three days, range two to seven days, P < .05).
'"/>




Related medicine news :

1. Statins reduce heart attacks
2. Statins reduce risks for angioplasty patients
3. Statins Found To Be Helpful For Patients With Arthritis
4. Long-Term Benefits Of Statins Questioned
5. Statins Not Effective In Treating Calcific Aortic Stenosis
6. Statins Gives New Hope for Increased Survival Rate of Heart Failure Patients
7. The Effects of Statins Questioned
8. Statins Taken For Reducing Cholesterol Found To Reduce Death Rate Associated With Heart Attack As Well
9. Study Finds No Link Between Statins And Breast Cancer Risk
10. Statins reduces cardiovascular risk but no cancer risk.
11. Statins Prescribed To Those Who Are At a Risk Of Developing A Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2016)... ... May 25, 2016 , ... Researchers from SUNY State College of Optometry won ... on visual evoked potential and human attention. The article, VEP and Human Attention: ... NOVA™ ERG and VEP Vision Testing System (Diopsys, Inc., Pine Brook, NJ) to ...
(Date:5/25/2016)... TX (PRWEB) , ... May 25, 2016 , ... ... the United States, named Dr. Anh Tat Nguyen, as the Medical Director of its ... the facility Medical Director of our new DeSoto location,” said Dr. James M. Muzzarelli, ...
(Date:5/25/2016)... New Jersey (PRWEB) , ... May 25, 2016 , ... ... specialized technology firm will be selling the device branded as Stern’s Real Time ... is geared to bedbugs to the hotel and motel industry, colleges for use in ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... According to ... that a group of people randomly assigned to reduce the amount of calories they ... 12 percent drop in body weight enjoyed better sleep, improved quality of life, and ...
(Date:5/24/2016)... ... 24, 2016 , ... BTC Media, a leading digital currency ... to be held in Nashville, Tennessee on September 7, 2016. , The conference ... the event will host teams from around the world, competing to build the ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... Non-invasive diagnostic test realizes the potential of ... be presented at Yissum’s booth, at IATI-BIOMED 2016 conference  ... the Hebrew University of Jerusalem announced today it ... MKI, the technology investment arm of Morris Kahn , ... early detection of multiple diseases by analyzing circulating DNA ...
(Date:5/23/2016)... May 23, 2016 Gamida Cell, ... treatment of cancer and orphan genetic diseases, announced today ... $4.4 million from the Israel Innovation Authority (formerly the ... of Economy and Industry. The mission of the Israel ... various industries, including science and technology, while stimulating economic ...
(Date:5/23/2016)... Conn. , May 23, 2016   ... has entered into an agreement with Egalet Corporation ... patent claims. As part of the agreement the ... and will enable all three companies to develop ... properties. "This agreement reflects the commitment ...
Breaking Medicine Technology: