Navigation Links
Statins Linked to Lower Risk of Infection

Researchers at Johns Hopkins may have discovered an unintended benefit in the drugs millions of Americans take to lower their// cholesterol: The medications, all statins, seem to lower the risk of a potentially lethal blood infection known as sepsis in patients on kidney dialysis.

Sepsis is the leading cause of death in non-coronary intensive care units in the United States, according to the U.S. Centers for Disease Control. It also poses serious risk for kidney patients undergoing regular dialysis treatments.

The Hopkins researchers cautioned that kidney dialysis patients should not necessarily ask their doctors to put them on statins until more studies are done to verify their findings.

Building on earlier, limited studies that suggested risk reduction in animals and some people, Professor of Medicine, Director of the Welch Center and senior author Neil R. Powe, M.D., and his Johns Hopkins team followed 1041 dialysis patients for 10 years, dividing the subjects into those taking statins and those not.

“Those taking statins had a 41 in a 1,000 chance of being hospitalized for sepsis, while the other group not taking statins had a 110 out of 1,000 risk. Although the overall absolute risk is relatively small, the statin group’s risk is dramatically lower,” says Rajesh Gupta M.D., the study’s lead author, who was a senior medical resident at Hopkins when the study was conducted.

Gupta says it remains unclear why or how statins work this way, “but the consistency of the findings with laboratory studies adds a lot of credence to the idea that statins are doing something substantial to reduce risk.”

“Statins are known to have an effect on the body’s immune system, but what that is exactly, and how many statin users it affects, is still not widely understood.”

Statins may regulate the immune response to infection or fight microbes directly, Powe suspects. The study’s authors also supp ose that statins may work like penicillin, since the first statin was originally derived from a fungus which, it is theorized, secretes a statin as a way to starve other competing microorganisms that require cholesterol to survive.

The study included patients from 81 dialysis clinics across 19 states. Only those enrollees who were admitted to the hospital with sepsis were counted, in order to rule out any subjects who became septic during an unrelated hospital stay.

Only 14 percent of those initially enrolled in the study were on statins. Out of the 1,041 patients, there were a total of 303 hospitalizations for sepsis.

Source-NewswiseBR>SRM/B
'"/>




Related medicine news :

1. Statins reduce heart attacks
2. Statins reduce risks for angioplasty patients
3. Statins Found To Be Helpful For Patients With Arthritis
4. Long-Term Benefits Of Statins Questioned
5. Statins Not Effective In Treating Calcific Aortic Stenosis
6. Statins Gives New Hope for Increased Survival Rate of Heart Failure Patients
7. The Effects of Statins Questioned
8. Statins Taken For Reducing Cholesterol Found To Reduce Death Rate Associated With Heart Attack As Well
9. Study Finds No Link Between Statins And Breast Cancer Risk
10. Statins Reduce Deaths And Strokes After Carotid Surgery
11. Statins reduces cardiovascular risk but no cancer risk.
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... 26, 2016 , ... The Woodlands at John Knox Village , Florida’s ... care for living and healing, celebrated its grand opening, today. The Woodlands at John ... provided by Empowered Staff. , “This is an incredibly fulfilling time for John Knox ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... for the Foundation Fighting Blindness, Long Island Chapter on June 4, 2016, 1:30-3:30 ... , Dr. Maisel, founder of Retina Group of New York , is ...
(Date:5/26/2016)... Wash. (PRWEB) , ... May 26, 2016 , ... ... trusted provider of comprehensive treatment for eating disorders, is opening a brand new ... will provide individuals ages 8-17 and their families with even more specialized eating ...
(Date:5/26/2016)... Miami, FL (PRWEB) , ... May 26, 2016 , ... ... day of events featuring guest speaker Dr. Adonis Maiquez MD, ABAARM. Dr. Adonis ... Anti-Aging and Regenerative Medicine, and a member of the Institute for Functional Medicine. , ...
(Date:5/26/2016)... ... May 26, 2016 , ... On May 23rd during the National Eye ... and international water advocate, was honored by Ashram, Inc. as the world’s foremost water ... knelt on the banks of the Nile to fill their red clay pots with ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016   ... endpoints demonstrating non-inferiority in overall bowel cleansing and superiority ... c leansing of the ... http://photos.prnewswire.com/prnh/20130829/633895-a ) , Norgine B.V. today announced new ... litre PEG and ascorbate bowel preparation) versus standard 2 litre PEG ...
(Date:5/24/2016)... -- Joe Marziani has joined VMS BioMarketing as senior vice president of sales, announced ... role, Marziani will lead the company,s business development and sales team, exploring new opportunities ... Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... Dutch surgeons have launched a ground-breaking medical ... and treat patients on a global scale. Medical professionals from ... Asia and the US have already signed up for ... in a totally secure environment. Education  "Imagine ... together with a surgeon at Harvard to treat a bomb victim ...
Breaking Medicine Technology: