Navigation Links
St. John's Wort in Pregnancy and Lactation

St. John’s wort (hypericum perforatum) is one of the five best-selling herbs in the United States. It is used by many to treat the symptoms of depression, and many prefer it to prescription medications such as Paxil? and Zoloft. //However, the herb has been the subject of growing concern about its interaction with birth control pills, the blood thinner warfarin, and cyclosporin, a medication used with those who have received organ transplants. A new study examining its effect on pregnant women and those who are breastfeeding contributes to the evidence that the product should be used with caution.

The new study, entitled “St. John’s Wort (hypericum perforatum): Is It Safe During Pregnancy, Breastfeeding and With Prescription Medications? A Systematic Review,” will soon be published in the Canadian Journal of Clinical Pharmacology. It is one in a series that systematically reviews the evidence relating to the safety of herbs commonly used during pregnancy and lactation.

Methodology The aim of the study was to systematically review the literature for evidence on the use, safety, and pharmacology of St. John’s wort focusing on issues pertaining to pregnancy and lactation. The investigators searched seven databases for reports relating to the herb. The databases included AMED, CINAHL, Cochrane CENTRAL, Cochrane Library, MedLine, Natural Database, and Natural Standard. Each database was examined in duplicate for data from its inception. Unpublished research and bibliographies were also included. Data were compiled according to the grade of evidence found.

Results The researchers found varying levels of scientific evidence on the efficacy of use for different conditions; low-level evidence of harm during pregnancy; and strong evidence of side effects during lactation. As St. John’s wort interacts with a number of medications due to its effect on cytochrome P450 enzymes, this may account for some of the findings.

Conclusions The researchers concluded:

§ Caution is warranted when using St. John’s wort during pregnancy and lactation.

§ St. John’s wort may interact with medications prescribed during pregnancy.

§ During pregnancy, a case study and some animal studies reported lower birth weights with use of St. John’s wort.

§ Strong scientific evidence showed that St. John’s wort consumption during lactation did not affect maternal milk production nor affect infant weight, but may cause colic, drowsiness or lethargy.

§ St. John’s wort showed strong scientific evidence of being an effective aid in combating mild to moderate depression and low-level evidence for other conditions.

Recommendations The authors urge women not to assume that because herbs are labeled “natural” that they are safe. They recommend all pregnant and lactating women consult a licensed, health care professional before consuming any herb or medicine in general, and St. John’s wort in particular. Finally, they recommend that any woman experiencing depression let their physician know immediately.

(ource: Newswise)
'"/>




Related medicine news :

1. Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
2. Pregnancy Blues
3. Smoking Delays Pregnancy
4. Pregnancy should not be confined
5. Pregnancy weight linked to breast cancer
6. Pregnancy complications indicate health problems
7. Pregnancy shouldnt be dissuaded in older age
8. Ginseng Associated with Pregnancy Risks
9. Predicting The Risk Of Preeclampsia During Pregnancy
10. Drugs Taken During Pregnancy Found To Affect Unborn Babies
11. Complications Of Pregnancy May Increase The Risk Of Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... that we intend to develop to enable prevention of a major side effect ... hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed ...
(Date:10/12/2017)... , ... October 12, 2017 , ... On Saturday, October ... treadmill relay – Miles by Moonlight to raise money for the American Heart Association ... more. , Teams will work together to keep their treadmills moving for 5 ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief ... advancements to physician colleagues, skilled nursing facility medical directors and other clinicians at ... of Wound Care." , "At many of these conferences we get to educate ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
(Date:10/4/2017)... LAWRENCE, Mass. , Oct. 4, 2017 /PRNewswire/ ... developer of single-use, self-contained, illuminating medical devices, today ... National Health Surveillance Agency (or Agência Nacional ... ®. The first single-use, cordless surgical retractor with ... ONETRAC provides optimal access, illumination and exposure of ...
(Date:10/2/2017)...  Eli Lilly and Company (NYSE: LLY ... quarter of 2017 on Tuesday, October 24, 2017. Lilly ... with the investment community and media to further detail ... will begin at 9 a.m. Eastern time. Investors, media ... of the conference call through a link that will ...
Breaking Medicine Technology: