Navigation Links
Spread of Breast Cancer can be stopped by a component in Turmeric

According to a study, curcumin, the major ingredient of turmeric and the compound that gives curry its mustard-yellow// colour, inhibits the spread of breast cancer to the lungs in mice. The study can be further investigated in human subjects.

The study, funded by the United States Department of Defence and conducted by researchers at the University of Texas M.D. Anderson Cancer centre, finds that curcumin seems to shut down a protein involved in the spread of breast cancer to other organs.

The study finds that curcumin, a non-toxic natural compound, not only prevents progression of the disease to the lungs, but also seems to be able to reverse the effects of paclitaxel or Taxol, a prescribed chemotherapy for breast cancer that, if used for too long, may actually trigger the spread of the disease. Taxol is so toxic that it activates a protein that produces an inflammatory response, which induces the spread of the disease. Curcumin indirectly acts on the protein and stops the spreading of breast cancer.

'We are excited about the results of the study and the possible implications for taking the findings into the clinic in the next several years,' said Bharat Aggarwal, Ph.D., professor of cancer medicine in M. D. Anderson's Department of Experimental Therapeutics. 'At this time, advanced breast cancer is a difficult foe to fight with few proven treatments available after surgery, chemotherapy and radiation therapy.'

In the study, 60 mice with breast cancer in four groups were randomly assigned either placebo, Taxol, curcumin, or the combination of Taxol and curcumin. Breast cancer was removed when it grew to a size of 10 mm.

In a previous study published in the Aug. issue of the journal Cancer, M.D. Anderson researchers found when a protein called nuclear factor-kapa B or NF-kB, which promotes the inflammatory response necessary to cause breast cancer to spread, was shut down, cancer cells were forced to commit suicide and cancer strains were unable to grow.

Researchers found curcumin acted indirectly to shut down NF-kB. Taxol activated the NF-kB in breast cancer cells, while curcumin stepped in and deactivated NF-kB by blocking a protein known as “IKK" that would otherwise turn on NF-kB, indicating Taxol and curcumin work against each other. Taxol produced the inflammatory response, triggering metastasis, while curcumin suppressed it, causing cell death.

Researchers caution that the current study is preliminary. Trials need to be performed to firm the preventive and therapeutic effects of curcumin in humans.

(Journal Clinical Cancer Research)
'"/>




Related medicine news :

1. Spreading its wings
2. Smallpox Would Spread Rapidly
3. Spreading knowledge to doctors about herbal medicine
4. Stopping Prostate Cancer from Spreading
5. Drug might prevent Prostate Cancer Spread
6. Circumcision Found To Prevent HIV Spread
7. New Way to Detect Spread of Skin Cancer
8. The Logic Behind The Spread Of SARS
9. Vaccine To Stop the Spread of Chickenpox
10. Minimizing The Risk Of HIV Spread
11. Drug might prevent Prostate Cancer Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... Sterling, VA (PRWEB) , ... April 21, 2017 ... ... hosting its first weeklong campaign, AWARE: A Week of Addiction and Recovery Education, ... emerging evidence in treating and preventing substance use disorders. , The mission ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... Health held the much anticipated Regional Primary Care Spring Symposium on April 1, ... the local medical community, offering physicians and healthcare providers an opportunity to learn ...
(Date:4/21/2017)... ... April 21, 2017 , ... Providing for loved ones before ... planning process, or where to even begin. “Now more than ever there are some ... properly protect yourself and your family,” said attorney Lisa Edgar Dickman, founder of the ...
(Date:4/21/2017)... ... April 21, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... in hopes of squashing a global crisis with solution to peace plan. Yisrayl says war ... because the plan is given by the Creator Himself. , Yisrayl says war drums ...
(Date:4/21/2017)... Houston, Texas (PRWEB) , ... April 21, 2017 ... ... repeal…. sound familiar? These are five common elements between the Obamacare program ... feral hog control program which uses Warfarin poison to kill hogs. , ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017 Global Surgical Drainage ... are tubes used to remove excess liquid and air. ... pus, urine, bile or lymph. Surgical drains are used ... such as orthopedics surgery, cardiovascular surgery, neurosurgery, plastic surgery ... post-surgery to prevent accumulation of fluid e.g. blood or ...
(Date:4/19/2017)... -- Companion animal vaccines are ... such as canine, avian and feline. ... as Attenuated Live Vaccines, Conjugate Vaccines, Inactivated Vaccines, ... Vaccines. Attenuated live vaccines are derived from disease-causing ... been weakend under laboratory conditions. Conjugate vaccines are ...
(Date:4/18/2017)... Cogentix Medical, Inc. (NASDAQ: CGNT), a global medical device ... markets with innovative and proprietary products, will release financial ... after the market close on Tuesday, May 2, 2017. ... call and webcast to discuss its financial results the ... p.m. Eastern Time (3:30 p.m. Central Time). Darin ...
Breaking Medicine Technology: