Navigation Links
Spread of Breast Cancer can be stopped by a component in Turmeric

According to a study, curcumin, the major ingredient of turmeric and the compound that gives curry its mustard-yellow// colour, inhibits the spread of breast cancer to the lungs in mice. The study can be further investigated in human subjects.

The study, funded by the United States Department of Defence and conducted by researchers at the University of Texas M.D. Anderson Cancer centre, finds that curcumin seems to shut down a protein involved in the spread of breast cancer to other organs.

The study finds that curcumin, a non-toxic natural compound, not only prevents progression of the disease to the lungs, but also seems to be able to reverse the effects of paclitaxel or Taxol, a prescribed chemotherapy for breast cancer that, if used for too long, may actually trigger the spread of the disease. Taxol is so toxic that it activates a protein that produces an inflammatory response, which induces the spread of the disease. Curcumin indirectly acts on the protein and stops the spreading of breast cancer.

'We are excited about the results of the study and the possible implications for taking the findings into the clinic in the next several years,' said Bharat Aggarwal, Ph.D., professor of cancer medicine in M. D. Anderson's Department of Experimental Therapeutics. 'At this time, advanced breast cancer is a difficult foe to fight with few proven treatments available after surgery, chemotherapy and radiation therapy.'

In the study, 60 mice with breast cancer in four groups were randomly assigned either placebo, Taxol, curcumin, or the combination of Taxol and curcumin. Breast cancer was removed when it grew to a size of 10 mm.

In a previous study published in the Aug. issue of the journal Cancer, M.D. Anderson researchers found when a protein called nuclear factor-kapa B or NF-kB, which promotes the inflammatory response necessary to cause breast cancer to spread, was shut down, cancer cells were forced to commit suicide and cancer strains were unable to grow.

Researchers found curcumin acted indirectly to shut down NF-kB. Taxol activated the NF-kB in breast cancer cells, while curcumin stepped in and deactivated NF-kB by blocking a protein known as “IKK" that would otherwise turn on NF-kB, indicating Taxol and curcumin work against each other. Taxol produced the inflammatory response, triggering metastasis, while curcumin suppressed it, causing cell death.

Researchers caution that the current study is preliminary. Trials need to be performed to firm the preventive and therapeutic effects of curcumin in humans.

(Journal Clinical Cancer Research)
'"/>




Related medicine news :

1. Spreading its wings
2. Smallpox Would Spread Rapidly
3. Spreading knowledge to doctors about herbal medicine
4. Stopping Prostate Cancer from Spreading
5. Drug might prevent Prostate Cancer Spread
6. Circumcision Found To Prevent HIV Spread
7. New Way to Detect Spread of Skin Cancer
8. The Logic Behind The Spread Of SARS
9. Vaccine To Stop the Spread of Chickenpox
10. Minimizing The Risk Of HIV Spread
11. Drug might prevent Prostate Cancer Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... ... be giving viewers the lowdown on sciatica in a new episode of "Success ... focuses on current events and innovation and investigates each subject in-depth with passion ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... LA (PRWEB) , ... October 12, 2017 , ... Planet ... in the U.S., announced today its plans to open a flagship location in Covington, ... occupy the former Rooms To Go store next to Office Depot in the Holiday ...
(Date:10/12/2017)... ... 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one of ... innovative new design of the shoulder pad. The shoulder pad provides optimal support ... your pain while using cold therapy. By utilizing ice and water that is circulated ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... DIEGO , Oct. 12, 2017 AVACEN ... recognized the company with their  2017 New Product Innovation Award ... based on extensive primary and secondary medical device market research ... Medical, through its first-to-market OTC, drug-free pain relief product, the ... unique approach to treating fibromyalgia widespread pain. ...
(Date:10/11/2017)... PARK, Calif. , Oct. 11, 2017  BioPharmX ... national scientific team that developed an innovative way to ... quantity of the delivery of new drugs. ... 2017 Fall Clinical Dermatology Conference will show how researchers ... General Hospital, Harvard Medical School used a suite of ...
(Date:10/11/2017)... , Oct. 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") ... Surgical facility in Las Piedras, Puerto Rico ... and blades. ... the facility sustained minor structural damage, temporary loss of ... Repairs have been completed, manufacturing operations have resumed, and ...
Breaking Medicine Technology: