Navigation Links
Sperm stem cells could be an alternative to embryonic stem cells in future

Stem cells are one of the fascinating areas of biology today, with new experiments continually replacing our existing knowledge about the potential applications of stem cells.

Scientists have now been successful in manipulating rat // sperm cells to behave like embryonic stem cells, which are capable of giving rise to various cell lineages such as a nerve cell, blood cell or a skin cell. In simple terms, the issue is all about making sperm cells pluripotent. The use of these cells in the treatment of diabetes and Parkinson’s disease is still in infancy due to unresolved ethical issues stemming from the source of these cells - human embryos or mouse cells.

Ordinarily, when germ stem cells divide into two cells, one "daughter" cell differentiates to become a sperm while the other remains a stem cell. The study represents a remarkable breakthrough as the fate of the male germ cells that give rise to sperms have been altered. Surprisingly, the stem cells even retained their capacity to transform into sperms after they were transplanted back into rat testes.

One of the breakthroughs in this study was the development of a new culture medium to grow the cells and the incorporation of a tag, the green fluorescent protein to help enable easy identification of germ cells from a mixture.

The findings of the present study have valuable clinical implications. It can pave way for the development of male contraceptives and a refinement in the animal models used in the study of infertility. It can even serve as an ideal alternative to embryonic stem cells.

"The ability to manipulate male germ-line stem cells and get them to grow and self-renew is a major step," said Dr. Garbers, a Howard Hughes Medical Institute investigator at UT Southwestern.

The researchers have now focused their attention towards genetic manipulation of the derived rat cells so that it can be extrapolated to produce ‘knock out mice’ that ca n be used in studying health and behavioral effects related to the knocked off genes.

The next step is to determine whether human male germ-line stem cells can also be conferred immortality under artificial laboratory conditions. Perhaps, someday, it might be possible to correct genetic defects in humans such as cystic fibrosis in the near future
'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. Now you can identify Sperm and Egg donors
3. Elevated Ozone Levels Hurt Sperm Count
4. Sperm washing helps couples
5. The Falling Sperm Count In Men
6. Anonymous Sperm Donor Traced On Internet
7. Declining Rates Of Sperm Donors Over The Past 5 Years
8. Sperm Retrieval, Difficult in Klinefelter’s Syndrome Patients after 35 Year
9. Researchers Identify Role Of Protein In Sperm Hyperactivation
10. Sperms not silent in the Female reproductive Tract
11. Non-Hormonal Male Contraceptive Based on Sperm Block Underway
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology: