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Sperm Retrieval, Difficult in Klinefelter’s Syndrome Patients after 35 Year

A Japanese researcher Dr. Hiroshi Okada with his colleagues conducted a study which proved that the Sperm extraction is very difficult after the age of 35 in case of men suffering from Klinefelter's syndrome. //

The study was conducted at the University School of Medicine in Tokyo. The results of this research were published in the journal Fertility and Sterility.

Klinefelter’s syndrome is a genetic syndrome in which a male patient has 22 chromosomes with one X, Y chromosome and an extra X chromosome.

Normally a male has 22 chromosomes with one X and one Y chromosome.

The patients suffering from this disorder has to undergo testicular sperm extraction before the age of 35 years. The most important feature of this disease is infertility.

They studied a group of 51 men all suffering from Klinefelter's syndrome and azoospermia (the absence of live sperm in semen).

They found that it was easy to obtain sperms from testicular tissue in 26 patients but failed to extract the sperms in case of 25 men.

The patients from whom sperm retrieval was possible were all in the average age of 31 years and in the failed case were all in the average age of 38 years.

The success rate was significantly higher in case of the younger patients below the age of 35 years.


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