Navigation Links
Sperm Cells attracted By Ovary Scent, Even in Weakened State

A new study by scientists at Indiana University Bloomington have reported that mouse sperm cells are capable of tracking the faintest of scents. //Sperm cells were bang on target, even when ovary extracts were extremely diluted.

"Sperm are known to exhibit chemotaxis toward extracts from various female reproductive organs, but the role of chemotaxis in reproduction is not known," said IUB Associate Professor of Chemistry Stephen C. Jacobson. "The chemicals that actually attract sperm have not been identified. Systematic study of various compounds released by the female reproductive organs under various conditions might further our understanding of these processes." Understanding why, how and when sperm are attracted to ovaries may help scientists understand problems with human conception.

"Defects in sperm chemotaxis may be a cause of infertility, and consequently, sperm chemotaxis could potentially be used as a diagnostic tool to determine sperm quality or as a therapeutic procedure in male infertility," Jacobson said.

The project is a collaboration between research groups led by Jacobson and IUB Distinguished Professor of Chemistry Milos V. Novotny. Their work led to the development of a "flow-through" device, a sort of liquid treadmill for sperm cells, which allows researchers to follow the lateral movement of sperm as the cells swim through a liquid medium.

The device feeds three streams of liquid into a single chamber. Beyond the chamber, flows are split into three exit streams. Flow rate can be regulated simply by raising or lowering the height of the source medium, in this case a buffer solution. The researchers affixed a microscope and camera to the device and then recorded video of the sperm during assays.

"We combined in a microfluidic device the ability to generate a chemical gradient with transporting sperm cells to evaluate sperm chemotaxis," Jacobson said. "The use of microfluidic devices appears to be an ideal approach for precisely controlling the chemical gradient and accurately tracking chemotactic events. This combination led to greater repeatability in the experimental conditions over the course of the assays, which is currently not possible with conventional assays. These results are an important first step toward having an easy-to-use platform to rapidly evaluate and quantify chemotaxis." The researchers hope their device will help other scientists more accurately examine the chemotaxis of all types of cells. The method also eliminates the phenomenon of "trapping," which causes study results to become ambiguous.

"The ability to differentiate chemotaxis from trapping helps to determine whether sperm were attracted to the test substance or the swim velocity was reduced close to the test substance," Jacobson said. "In the latter case, the test substance may have had a negative influence on the sperm, resulting in suppression of their movement." Novotny is the Lilly Chemistry Alumni Chair in the Indiana University Bloomington Department of Chemistry, where he also directs the Institute for Pheromone Research.
'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. Now you can identify Sperm and Egg donors
3. Elevated Ozone Levels Hurt Sperm Count
4. Sperm washing helps couples
5. The Falling Sperm Count In Men
6. Anonymous Sperm Donor Traced On Internet
7. Declining Rates Of Sperm Donors Over The Past 5 Years
8. Sperm stem cells could be an alternative to embryonic stem cells in future
9. Sperm Retrieval, Difficult in Klinefelter’s Syndrome Patients after 35 Year
10. Researchers Identify Role Of Protein In Sperm Hyperactivation
11. Sperms not silent in the Female reproductive Tract
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... , ... June 24, 2016 , ... June 19, 2016 ... dangers associated with chronic pain and the benefits of holistic treatments, Serenity Recovery ... are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
(Date:6/24/2016)... ... ... Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair ... hour by 2020 and then adjusting it yearly to increase at the same rate as ... the wage floor does not erode again, and make future increases more predictable. , The ...
(Date:6/24/2016)... York, NY (PRWEB) , ... June 24, 2016 ... ... publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as a ... that “the most beautiful women in the world, and the most handsome men, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Medical Market Analysis 2016 - Forecast to 2022" report ... The report contains up to date financial data derived from ... of major trends with potential impact on the market during ... market segmentation which comprises of sub markets, regional and country ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: