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Soy Protein Study Generates New Findings

luations of women in the study with metabolic syndrome (MS) a clustering of at least three CVD risk factors: high blood pressure, high triglycerides, low levels of HDL cholesterol (good cholesterol), high glucose, or abdominal obesity (large waist measurement). When compared to women in the study without the syndrome, those with MS had lower levels of high-density lipoprotein cholesterol and higher levels of triglycerides without significant differences in total cholesterol. However, there were significant differences in major lipoprotein subclass measures, showing that women with MS had smaller mean LDL size, higher LDL participle concentration, and smaller mean HDL size; all factors putting them at increased risk for CVD.

During the study, investigators also compiled data on recruitment into the clinical trail. Published this month in Ethnicity and Disease, Lindenstruth’s analysis—“Recruitment of African American and White Postmenopausal Women into Clinical Trials: The Beneficial Effects of Soy Trial Experience”—shows that African American and white women differed significantly in their response to various forms of mass media and personalized techniques employed to recruit participation in the clinical trial. The most effective mechanism for recruiting African American women was direct mail (52%), followed by radio (15%); newspapers were less effective. Conversely, white women responded best to newspaper ads (36%) followed by direct mail (32%); and radio was less effective. These strategies were more effective than the personalized techniques—health fairs, provider referrals, newsletters and churches.

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