Navigation Links
Soy Protein Study Generates New Findings

The Beneficial Effects of Soy Trial (BEST), a Baltimore-based randomized controlled study of dietary soy, has yielded an array of results// pertaining to cholesterol reduction, metabolic syndrome, and recruitment for clinical trials.

The multi-disciplinary study team, led by Johns Hopkins University School of Nursing (JHUSON) researcher and lead investigator Jerilyn K. Allen, ScD, RN, reports its findings this month in Menopause and Ethnicity and Disease and today at the American Heart Association 2006 Scientific Sessions.

In “Effect of Soy Protein-Containing Isoflavones on Lipoproteins in Postmenopausal Women” now appearing online in Menopause, Allen and co-authors report that among their BEST study group—216 healthy postmenopausal African American and white women with moderately elevated low-density lipoprotein (LDL) cholesterol levels—those who received isolated soy protein containing isoflavones experienced a significant decrease in total cholesterol, LDL cholesterol, and lipoprotein particles. LDL levels decreased by an average of 3.3%, LDL particles decreased by 5.6%, and beneficial high-density lipoprotein cholesterol (HDL) increased 4.4%. Noting that because lipoprotein levels often increase as a consequence of menopause, Allen cautions that while soy protein alone will not lower cholesterol with the same effectiveness as medications, “the modest effects of soy protein on LDL cholesterol and LDL particle number may be beneficial for heart health in postmenopausal women who do not require statins or other medications to control their levels.”

At the American Heart Association meeting this week, Allen and JHUSON co-authors Sarah Szanton, Kathleen Lindenstruth, and Carol Curtis reported additional BEST study findings on factors associated with cardiovascular disease (CVD). In “Effect of Metabolic Syndrome on Lipoprotein Subclass Particle Size and Concentration in Postmenopausal Women,” the investigators reported on their eva luations of women in the study with metabolic syndrome (MS) a clustering of at least three CVD risk factors: high blood pressure, high triglycerides, low levels of HDL cholesterol (good cholesterol), high glucose, or abdominal obesity (large waist measurement). When compared to women in the study without the syndrome, those with MS had lower levels of high-density lipoprotein cholesterol and higher levels of triglycerides without significant differences in total cholesterol. However, there were significant differences in major lipoprotein subclass measures, showing that women with MS had smaller mean LDL size, higher LDL participle concentration, and smaller mean HDL size; all factors putting them at increased risk for CVD.

During the study, investigators also compiled data on recruitment into the clinical trail. Published this month in Ethnicity and Disease, Lindenstruth’s analysis—“Recruitment of African American and White Postmenopausal Women into Clinical Trials: The Beneficial Effects of Soy Trial Experience”—shows that African American and white women differed significantly in their response to various forms of mass media and personalized techniques employed to recruit participation in the clinical trial. The most effective mechanism for recruiting African American women was direct mail (52%), followed by radio (15%); newspapers were less effective. Conversely, white women responded best to newspaper ads (36%) followed by direct mail (32%); and radio was less effective. These strategies were more effective than the personalized techniques—health fairs, provider referrals, newsletters and churches.



Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:

(Date:10/13/2015)... ... October 13, 2015 , ... ... Debbie Vereb has been named the organization’s Executive Vice President of Operations, and ... hired to key leadership roles in the company. , Debbie Vereb’s appointment to ...
(Date:10/13/2015)... ... 13, 2015 , ... Curly Hair Solutions® is thrilled to ... an exhibition featuring the newest products and services to hit the market for ... more excited to unveil their recent partnership with Trade Secrets, a leading Canadian ...
(Date:10/13/2015)... , ... October 13, 2015 ... ... LLC presented results from GyencoloGeneTM, the world’s first commercially-available next-generation sequencing laboratory ... FIGO World Congress of Gynecology and Obstetrics in Vancouver, BC, Canada. ...
(Date:10/13/2015)... NY (PRWEB) , ... October 13, 2015 , ... ... her award winning programs Elder Care Doula Training and End of Life ... elderly in a holistic model, physically, spiritually and emotionally. Based on her ...
(Date:10/12/2015)... ... October 13, 2015 , ... Career Step, ... the release of its new Professional Medical Coding and Billing with Applied PCS ... ICD-10-CM and ICD-10-PCS code sets, earn the Certified Professional Coder (CPC) and Certified ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... 12, 2015  CME Group,s Center for Innovation ... of Theranos, is the 11 th recipient of the ... revolutionary blood diagnostics company, Theranos , to change health ... a new era of preventive care. CME Group will present ... Conference in Naples, Florida , on ...
(Date:10/12/2015)... 12, 2015 --> ... Review, H2 2015 market research report provides data ... by identifying new targets and MOAs to produce ... . --> . ... across 62 pages, analyzing 6 companies, 8 drug ...
(Date:10/12/2015)... October 12, 2015 --> ... on the global vital signs monitoring devices market in its ... Analysis and Opportunity Assessment 2015-2025." The global vital signs monitoring ... of 9.5% and 9.2% in terms of value and volume, ... FMI offers major insights in detail in this report. ...
Breaking Medicine Technology: