Navigation Links
Soy Isoflavones Linked to Lower Prostate Cancer Risk

Increased intake of soy isoflavones significantly reduced the risk of prostate cancer amongst Japanese men by as much as 50 per cent//, says a new study.

"To our knowledge, this is the first prospective study to report an inverse association between isoflavone and localized prostate cancer in Japanese, whose intake of soy food is high," wrote lead author Norie Kurahashi from Japan's National Cancer Center.

Over half a million news cases of prostate cancer are diagnosed every year world wide, and the cancer is the direct cause of over 200,000 deaths. More worryingly, the incidence of the disease is increasing with a rise of 1.7 per cent over 15 years.

"The incidence of prostate cancer is much lower in Asian than Western populations… Although isoflavones have been suggested to show a preventive effect against prostate cancer in animal experiments, the results of epidemiologic studies are inconsistent," stated the researchers in the journal Cancer Epidemiology Biomarkers & Prevention.

The study recruited 43,509 Japanese men (average age 57) with a generally high soy isoflavone intake. Dietary assessment was performed using a validated 147-item food frequency questionnaire.

During the five years of follow-up, 307 men were newly diagnosed with prostate cancer (74 cases were advanced), and 220 cases were organ localized. While no relationship between total prostate cancer risk and dietary intakes of genistein, daidzein, miso soup, and soy food was observed, all four food items were associated with significant risk reduction for localised prostate cancer.

The highest intake of soy isoflavones (at least 32.8 milligrams of genistein per day) had a 40 per cent reduced risk compared to those with the lowest intake (less than 13.2 mg/d), the researchers found.

"These results were strengthened when analysis was confined to men ages greater than 60 years, in whom isoflavones and soy food were as sociated with a dose-dependent decrease in the risk of localized cancer, with relative risks for men in the highest quartile of genistein, daidzein, and soy food consumption compared with the lowest of 0.52, 0.50, and 0.52, respectively," stated the researchers.

In contrast, increased isoflavone intake was found to enhance the risk of advanced prostate cancer, said Kurahashi.

The mechanism behind the benefits was linked to the weak oestrogenic activity of soy isoflavones, which may act to reduce testosterone levels and inhibit 5á-reductase - an enzyme involved in the metabolism of testosterone.

"Given that Japanese consume isoflavones regularly throughout life, we do not yet know the period during which the effects of isoflavones on prostate cancer are preventive," concluded the researchers.

Source-Bio-Bio Technology

Related medicine news :

1. Postmenopausal Women May Benefit From Isoflavones Therapy
2. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
3. Cough Syrup Ingredient Linked to Stroke
4. Irregular Periods Linked to Diabetes
5. Hormones Linked To Migraines
6. Triglycerides Linked To Stroke Risk
7. Smoking Linked To Low Infant Birth Weight
8. Nausea Linked To Anxiety And Depression
9. Painkiller Linked to Deaths
10. High Levels of Protein Linked to Brain Shrinkage
11. Snoring Linked To Headaches
Post Your Comments:

(Date:11/27/2015)... CO (PRWEB) , ... November 27, 2015 , ... According ... cities are not changing the way that they are handling security in light of ... police and security presence in an attempt to stop an attack from reaching U.S. ...
(Date:11/27/2015)... ... 2015 , ... An inventor, from Hopkinsville, Ky., thought there ... home, so he invented the patent-pending ELECTRONIC M.D. , The ELECTRONIC M.D. provides ... so, it could help to prevent potential overdose situations. As a result, it ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... 27th edition of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, ... The digital component is distributed nationally, through a vast social media strategy and ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with the ... 2016 Building Better Radiology Marketing Programs meeting will showcase some of the ... 2016, at Caesars Palace in Las Vegas with a pre-conference session on a ...
(Date:11/27/2015)... ... November 27, 2015 , ... The moment you stop improving ... only fulfilling the needs of advisers and clients but going above and beyond ... top-tier customer service. However, there's always room for improvement, which is why the ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... A new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy ... new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for ... new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for ... has found that immunotherapy can be efficiently ...
(Date:11/26/2015)... Research and Markets ( ) ... Future Horizons and Growth Strategies in the Japanese ... Segment Forecasts, Competitive Intelligence, Emerging Opportunities" report ... --> This new 247-page report ... drug monitoring market, including emerging tests, technologies, instrumentation, ...
(Date:11/26/2015)... , Nov. 26, 2015 Research and Markets ... "Advanced Wound Care Market by Type (Dressings, Therapy ... User (In-Patient Facility, Out-Patient Facility), and Geography - Global ... --> --> The ... definition and forecast of the global advanced wound care ...
Breaking Medicine Technology: