Navigation Links
Sour Taste Sensors Identified

The cells and receptors responsible for sour taste have been identified by Howard Hughes Medical Institute researcher Charles S. Zuker and Nicholas J.P. Ryba //at the National Institutes of Health after seven years of working together to identify the cells, receptors and signaling mechanisms for three of the five tastes humans can sense -- sweet, bitter, and umami. The sour taste sensors have been found to be the primary gateway in all mammals for the detection of spoiled and unripe food sources. The receptor is found in a subpopulation of taste receptor cells of the tongue that do not function in sweet, bitter, or umami (the taste of monosodium glutamate) taste, the researchers report in the August 24, 2006, issue of the journal Nature.

This finding is "very satisfying," said Zuker, "because it seals the case that we had built before with sweet, bitter, and umami, showing that each taste is mediated by fully dedicated sensors." A contrasting view held that individual tongue cells detect more than one taste modality, with the quality of the taste being encoded in a complicated pattern of nerve signals sent to the brain.

The hunt for the sour receptor began with a search of DNA and protein sequence databases. Angela Huang, a graduate student in Zuker's lab at the University of California, San Diego, and the lead author of the paper, screened the mouse genome for all of the genes encoding proteins that have transmembrane domains -- sections of the protein that allow the protein to be located in cell membranes.

"That screen narrowed the list significantly, from 30,000 to about 10,000," Huang said. She then used what Zuker calls "a stroke of ingenuity" to reduce the list further. Proteins that could detect sour compounds are likely to be found only in small numbers of tissues, including taste cells in the tongue. Huang therefore eliminated from the list all those proteins that are expressed in many different tissues. "That got it do
'"/>




Page: 1 2 3

Related medicine news :

1. Hunger Found To Influence Taste
2. Understanding The Link Between Hunger and Taste
3. Understanding The Role Of Olfaction In Taste
4. More About The Coffee Bean Than Just A Heavenly Taste and Smell
5. Cocoa: Doesn’t Taste Like Red Wine But Has Benefits Like It
6. Punjabis Transfer Taste From Chicken To Prawns
7. Genetic Variation In Bitter-Taste Receptor Gene Increases Alcoholic Risk
8. Functional Taste Cells Cultured In Vitro
9. Twins Taste Trend Inherited – Research Say
10. Sensitive Taste Buds Can Be The Blame for LilOne Not Eating Vegetables
11. Discerning Sour Taste
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sour Taste Sensors Identified

(Date:7/21/2014)... Cannabis Now Magazine recently announced that ... summer. During these festivals, they will strengthen their relationship ... resources to attendees in an effort to continue their ... legitimate and beneficial side of cannabis. , The publication ... the Kush Expo in Anaheim, the Champs Trade Show ...
(Date:7/21/2014)... NY (PRWEB) July 21, 2014 The ... (“League”) and 1199SEIU United Healthcare Workers East (“1199SEIU”) today ... addresses critical issues facing healthcare providers and their employees. ... which will require ratification by League and 1199SEIU members, ... years. In addition, all existing worker benefits, including healthcare ...
(Date:7/21/2014)... human nature to hate losing. , Unfortunately, it,s ... abandoning a solid strategy and thus increasing your chances ... conclusion of a Brigham Young University study published this ... finding is based on an analysis of two decades ... focused on whether coaches adjusted their personnel following games ...
(Date:7/21/2014)... 21, 2014 Ticket Down is ... at the Sun Life Stadium in Miami Gardens, Florida ... between Brazil and Argentina is one that has been going ... rivalries are forming with each passing day. One rivalry that ... Brazil and another South American nation, Colombia. The two teams ...
(Date:7/21/2014)... that HIV and its monkey equivalent, SIV, gain a ... making it difficult to completely eliminate the virus even ... report that SIV can become entrenched in tissues fewer ... detectable in blood plasma (the liquid part) or blood ... Ph.D., of Beth Israel Deaconess Medical Center and the ...
Breaking Medicine News(10 mins):Health News:Cannabis Now Magazine Hits the Marijuana Festival Circuit and Sponsors Two Major Events 2Health News:League of Voluntary Hospitals and Homes and 1199SEIU Reach New Four-Year Collective Bargaining Agreement 2Health News:League of Voluntary Hospitals and Homes and 1199SEIU Reach New Four-Year Collective Bargaining Agreement 3Health News:'Moral victories' might spare you from losing again 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Reports Huge Demand for Colombia vs. Brazil Tickets at Sun Life Stadium in Miami in Early September 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Reports Huge Demand for Colombia vs. Brazil Tickets at Sun Life Stadium in Miami in Early September 3Health News:NIH-supported scientists demonstrate very early formation of SIV reservoir 2
... propose alternative that won,t burden patients, workers, ... Inc., which filed for bankruptcy protection in December, ... workers to ease its continued,financial troubles. However, caregivers ... care. At a rally, workers will unveil their ...
... Healthation CEO Scott Kornhauser,announced the appointment of ... today. Mr. Hebert was a former consulting partner ... complex solutions in the healthcare,industry., Mr. Hebert,s ... and growing market share for Healthation. Prior to,joining ...
... price to the regional, state, or ... nationwide averages, ... on their website, http://www.alijor.com . Users can now view,price summaries ... Provider" feature, patients can compare prices for,consultations, appointments, and follow up ...
... A compound found in grape seed extract reduces plaque ... of Alzheimer,s disease, new research shows. The study appears ... of Neuroscience . , Lead study author Giulio ... and colleagues found that the grape seed extract prevents ...
... cut body fat for those at risk of insulin resistance ... metformin slows the onset of early puberty and reduces the ... conditions, a Spanish study concludes. , "The findings indicate ... when puberty is faster in girls, the appearance of menses ...
... ROCHESTER, Minn., June 17 Researchers have,long suspected ... might affect survival rates following heart attack. In ... researchers present new data,suggesting that people with lower ... after heart attack than more affluent, educated people. ...
Cached Medicine News:Health News:Hospital Workers Say Concessions Will Diminish Patient Care 2Health News:Study indicates grape seed extract may reduce cognitive decline associated with Alzheimer's disease 2Health News:Study indicates grape seed extract may reduce cognitive decline associated with Alzheimer's disease 3Health News:Diabetes Drug May Prevent Early Puberty in Young Girls 2Health News:People With Lower Incomes, Lower Education Levels Have Higher Death Rates After Experiencing Heart Attack 2Health News:People With Lower Incomes, Lower Education Levels Have Higher Death Rates After Experiencing Heart Attack 3
(Date:7/21/2014)... , July 21, 2014 Thoratec Corporation ... device-based mechanical circulatory support therapies to save, support and ... its operating results for the second quarter of fiscal ... company will hold a conference call to discuss its ... parties, at 1:30 p.m., Pacific Daylight Time (4:30 p.m., ...
(Date:7/21/2014)... 2014  EHE International, the recognized leader in preventive ... network, today announced that Dignity Health Medical Group Nevada, ... has been named an EHE-certified preventive care center. Through ... region now have greater access to EHE,s ... "EHE is proud to add Dignity ...
(Date:7/21/2014)... , July 21, 2014 /PRNewswire-iReach/ -- Top ... GPM Pediatrics responds to an article, which suggests that ... Logo - http://photos.prnewswire.com/prnh/20140718/128611 ... about giving coffee to children, but now it happens ... . A new study, published in the journal Pediatrics, ...
Breaking Medicine Technology:Thoratec Schedules Second Quarter Conference Call, Webcast 2EHE International Certifies Dignity Health Medical Group Nevada, LLC as Its Newest Partner 2Dr. Michael Gabriel a Brooklyn Pediatrician Comments on an Article, Which Suggests Caffeine May Be Dangerous for Children 2
... Leading orthopaedic surgeon Simon Moyes has launched a ... from the surgeon,s viewpoint and from inside the joint. ... kind, has been developed by Simon Moyes along ... devices, and is aimed at students, junior surgeons and patients ...
... Jan. 11, 2012  SuccessEHS announces that its newest release ... times when compared to previous releases.  The company has ... Record (EHR) and Practice Management software solution ... The upcoming release will focus on user efficiency and ...
Cached Medicine Technology:Simon Moyes Pioneers New Keyhole Surgery Website 2Newest SuccessEHS Release to Increase Physician Software Usability 2Newest SuccessEHS Release to Increase Physician Software Usability 3
Wet-Field Hemostatic Eraser bipolar tip, packsize is 10/box....
... of foldable intraocular lenses. The instrument consists ... under the implant and divides the implant ... support both halves of the lens so ... the anterior chamber is avoided. The instrument ...
Shafts angled 8 mm from tip to bend with smooth jaws. Flat, cross action handle with holes and dull finish....
Bi-angled insertion jaws designed to enhance surgeon comfort and efficiency. Reverse action releases lens when handle is compressed. Made in titanium....
Medicine Products: