Navigation Links
Software Improvements in Breast MRI Scans

According to a new study,using commercially available software to enhance breast scans done by magnetic resonance imaging (MRI) reduces the number of false positive identifications of malignant tumors and the subsequent need for biopsies.

Teresa Williams, M.D., and colleagues at the Seattle Cancer Care Alliance and the University of Washington Medical Center did a retrospective examination of 154 breast lesions deemed suspicious by radiologists that were only visible on MRI and that had been biopsied under MRI guidance.

They compared the findings and recommendations made by radiologists at the time to new findings using computer-aided enhancement (CAE) software to enhance and evaluate the visible response to contrast agents absorbed by breast tissue.

False positives were reduced by 23 percent when CAE was set to its highest enhancement level, according to the study, which is published in the July edition of the journal Radiology. Williams was a medical resident in radiology at the Seattle Cancer Care Alliance (SCCA) when the research was done. She is now a fellow in pediatric radiology at Childrens Hospital and Regional Medical Center in Seattle.

In summary, our findings suggest that CAE has the potential to improve the discrimination of benign and malignant breast MRI lesions, the authors wrote. We believe that CAE is useful as a tool to supplement the radiologists subjective interpretation, but should not be relied upon exclusively to guide management.

There are challenges associated with breast MRI and one is the time it takes to process and evaluate the many images acquired, said Constance Lehman, M.D., corresponding author and director of radiology at the SCCA.

Computer software programs such as the one evaluated in our study can assist us in interpreting breast MRI scans more easily. Our study suggests that the information provided may improve our ability to distinguish between benign and malignant lesions. Currently, MRI scans are used in addition to mammography when radiologists need a better view of tissue they suspect may be malignant.

MRI as an adjunct to mammography also is standard practice at the SCCA for women who are at high risk for breast cancer and to examine the other, or contralateral, breast of women who are newly diagnosed.

One particular challenge in breast MRI is the interpretation of the morphology and kinetic features the amount of contrast agent absorbed by breast tissue over time on multiple imaging series. Typically, a woman will receive one scan without contrast agent and two more after contrast has been administered. One key analysis function performed by CAE is automatic kinetic assessment.

The detailed CAE lesion kinetic information differs substantially from that obtained by conventional manual placement of a region of interest, the authors wrote. This is because CAE generates detailed data for the entire lesion versus only a portion of the lesion that is highlighted by region-of-placement.

The lesions in the study had been identified and biopsied during 2001-2004 and came from 125 women ages 27-86. They were processed using CADstream 3.0, a CAE system developed by Confirma, Inc. of Kirkland, Wash. The presence of CAE threshold enhancement was sensitive for malignancy in 38 of the 41 malignant lesions examined using the software, according to the study.

However, the software did not perform perfectly; it failed to confirm the malignancy of the three lesions. Given the presence of three false-negative lesions, a finding deemed suspicious by the radiologist should be further evaluated regardless of the enhancement features determined by CAE, according to the study.

Williams said she advocates the use of CAE software analysis of MRI scans as an aid to radiologists interpretations. The software is already commercially available and it h as shown it is useful in reducing the false positive rate of breast MRI, she said.




'"/>




Related medicine news :

1. Africa Set to Control Malaria Using Specialized Software
2. India, a Hot Destination? Software or Sex, Indians are the Best!
3. Safe Software A Must For Doctors
4. New Software to Help Patients
5. Software Tools & Fonts in Seven Indian Languages
6. Computer Software Less Reliable Than Radiologists Eyes in Detecting Cancerous Tumors
7. Software System to Improve the Function of Retinal Implants
8. Simple Procedural Improvements Can Improve Care Of Stroke Patients
9. Improvements in ADHD with Fish Oil
10. University Envisages Improvements in Artificial Arm
11. Results for Wet Age-Related Macular Degeneration Show Significant Vision Improvements
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/17/2017)... NY (PRWEB) , ... January 17, 2017 , ... ... Magazine’s fastest-growing private companies and ranked among the top US security companies for ... of Directors. This announcement brings a year-long independent board nomination process to ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... Montclair State University’s Athletic Training Education program forged a relationship built upon the ... Education Program, which is consists of both student members and certified members of ...
(Date:1/16/2017)... , ... January 16, 2017 , ... California Southern University ... has served on CalSouthern’s Board of Trustees and as a core faculty member, teaching ... has been a professor of psychology at Pepperdine University, where he earned his Doctor ...
(Date:1/16/2017)... (PRWEB) , ... January 16, 2017 , ... With the ... opened on January 8 for use by sports teams and the general public. Built ... volleyball courts that can also be converted into basketball or pickleball courts. The space ...
(Date:1/16/2017)... Smithtown, New York (PRWEB) , ... January 16, ... ... group, SightMD today announced the addition of Victor Giamos, MD to ... Officer of SightMD and Managing Partner at North Shore Eye Care, a division ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... ROCKLAND, Mass. , Jan. 17, 2017  EMD ... Germany , in the U.S. and ... R. Smith has joined the company as Senior ... In this role, Mr. Smith will oversee the Fertility ... Fertility Technologies division, which launched its first product last ...
(Date:1/17/2017)... -- In a preview of the upcoming Society of Critical Care ... developer of the NephroCheck Test, today highlighted events studying current ... at risk of developing moderate to severe acute kidney injury ... Hawaii Convention Center in ... AKI is one of the top 10 hospital in-patient ...
(Date:1/17/2017)... 2017 Interpace Diagnostics Group, Inc., (NASDAQ: ... diagnostic tests and pathology services for evaluating risks of ... dated January 13, 2017 from the NASDAQ Listing Qualifications ... the requirement of the NASDAQ Stock Market to maintain ... The letter noted that for the last ...
Breaking Medicine Technology: