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Soft Drink Additive Could Cause Cell Damage

A new scare over soft drinks is in the making following revelations that a common preservative found in such popular brands like Fanta and Pepsi Max has the ability to switch off vital parts of DNA. That would mean serious cell damage.

For when parts of DNA are disabled, as it were, it could eventually lead to cirrhosis of the liver and degenerative diseases such as Parkinson's.

Concerns centre on the safety of E211, known as sodium benzoate, a preservative used for decades by the 74bn global carbonated drinks industry. Sodium benzoate derives from benzoic acid. It occurs naturally in berries, but is used in large quantities to prevent mould in soft drinks such as Sprite, Oasis and Dr Pepper. It is also added to pickles and sauces.

Sodium benzoate has already been the subject of concern about cancer because when mixed with the additive vitamin C in soft drinks, it causes benzene, a carcinogenic substance. A Food Standards Agency survey of benzene in drinks last year found high levels in four brands which were removed from sale.

Now, an expert in ageing at Sheffield University, who has been working on sodium benzoate since publishing a research paper in 1999, has decided to speak out about another danger. Professor Peter Piper, a professor of molecular biology and biotechnology, tested the impact of sodium benzoate on living yeast cells in his laboratory. What he found alarmed him: the benzoate was damaging an important area of DNA in the "power station" of cells known as the mitochondria.

He said, These chemicals have the ability to cause severe damage to DNA in the mitochondria to the point that they totally inactivate it: they knock it out altogether. "The mitochondria consumes the oxygen to give you energy and if you damage it - as happens in a number if diseased states - then the cell starts to malfunction very seriously. And there is a whole array of diseases that are now being tied to damag
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