Navigation Links
Sodium Nitrate Destroys The Bacteria That Plugs The Air Passage In CF Patients

Sodium nitrite is commonly used as a preservative to cure meat products. A study shows that it has the ability to kill the bacteria that causes thickening of the mucus in the lungs of cystic fibrosis patients. // The experiment is carried out in laboratory animal models.

Daniel Hassett, Ph.D., an associate professor of genetics at the University of Cincinnati said that Pseudomonas aeruginosa is the bacteria that form mucus and threatens the lives of CF (Cystic Fibrosis) patients.

P. aeruginosa, multiplies extensively in the lungs and airways of CF patients resulting in the formation of antibiotic and phagocyte-resistant biofilms. This is due to a mutation in the gene mucA that the bacteria are able to form the lung-clogging mucus.

In the laboratory when small amount of acidified sodium nitrite is added to the suspension containing mucoid bacteria it results in the conversion of the mucus in to gaseous nitric oxide. This was reported online in the Journal of Clinical Investigation. The mucoid bacteria are killed because of the gaseous nitric oxide.

Bacteria, which lack the mucA mutation, are not affected, but about 87% of the bacteria isolated from the lungs of CF patients have mucA mutation. Hence sodium nitrate can be used as one of the way to destroy bacteria that are resistant to antibiotics and white blood cells.

White blood cells are unable to destroy the bacteria because they're enmeshed in the thick mucous and the White blood cells end up destroying the lungs and airway tissue. The biofilms blocks the entire airway passage and deprives the tissue of oxygen ultimately killing it.

It also showed that Nitrite and its derivatives does not have any ill effects on the cultured human airway epithelia. The researchers say that nitrites could be inhaled and be part as the CF therapy. The patients can continue with this therapy until they develop the normal strains and starts showing signs of improvement. L ater on the patients can be administered conventional antibiotics.

But the researchers indicate the necessity of further studies to rule out toxic side effects before the treatment is available to CF patients.


'"/>




Related medicine news :

1. Sodium nitrite salt intake found to increases blood flow
2. Americans Consume Far Too Much Salt and Sodium
3. Helicobacter pylori effectively killed by Sodium nitrite
4. Sodium Hyaluronate Shows Promise In Treatment Of Shoulder Pain
5. Cadila Gets Tentative USFDA Nod For Pravastatin Sodium Tablets
6. Altered Sodium Channel Function Linked to Heart Failure
7. Low Blood Sodium When Born Linked to Long Term Sodium Intake
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Stroke Destroys Nearly 32, 000 Neurons In Just A Second!
10. New Technique Destroys Kidney Tumors By Freezing Them
11. New Hand Gel Destroys Bird Flu Virus
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA ... the Road To Recovery® program to drive cancer patients to and from their cancer ... ensure the highest quality of life and ongoing independence. Getting to and from ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and ... women in the world, and the most handsome men, look naturally attractive. Plastic ...
(Date:6/24/2016)... ... 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... service members that have been wounded in battle and their families. Venture Construction Group ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
(Date:6/23/2016)... , June 23, 2016 Research ... MEMS Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data ... analysis. Assessment of major trends with potential impact on the ... analysis of market segmentation which comprises of sub markets, regional ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
Breaking Medicine Technology: