Navigation Links
Sodium Nitrate Destroys The Bacteria That Plugs The Air Passage In CF Patients

Sodium nitrite is commonly used as a preservative to cure meat products. A study shows that it has the ability to kill the bacteria that causes thickening of the mucus in the lungs of cystic fibrosis patients. // The experiment is carried out in laboratory animal models.

Daniel Hassett, Ph.D., an associate professor of genetics at the University of Cincinnati said that Pseudomonas aeruginosa is the bacteria that form mucus and threatens the lives of CF (Cystic Fibrosis) patients.

P. aeruginosa, multiplies extensively in the lungs and airways of CF patients resulting in the formation of antibiotic and phagocyte-resistant biofilms. This is due to a mutation in the gene mucA that the bacteria are able to form the lung-clogging mucus.

In the laboratory when small amount of acidified sodium nitrite is added to the suspension containing mucoid bacteria it results in the conversion of the mucus in to gaseous nitric oxide. This was reported online in the Journal of Clinical Investigation. The mucoid bacteria are killed because of the gaseous nitric oxide.

Bacteria, which lack the mucA mutation, are not affected, but about 87% of the bacteria isolated from the lungs of CF patients have mucA mutation. Hence sodium nitrate can be used as one of the way to destroy bacteria that are resistant to antibiotics and white blood cells.

White blood cells are unable to destroy the bacteria because they're enmeshed in the thick mucous and the White blood cells end up destroying the lungs and airway tissue. The biofilms blocks the entire airway passage and deprives the tissue of oxygen ultimately killing it.

It also showed that Nitrite and its derivatives does not have any ill effects on the cultured human airway epithelia. The researchers say that nitrites could be inhaled and be part as the CF therapy. The patients can continue with this therapy until they develop the normal strains and starts showing signs of improvement. L ater on the patients can be administered conventional antibiotics.

But the researchers indicate the necessity of further studies to rule out toxic side effects before the treatment is available to CF patients.


'"/>




Related medicine news :

1. Sodium nitrite salt intake found to increases blood flow
2. Americans Consume Far Too Much Salt and Sodium
3. Helicobacter pylori effectively killed by Sodium nitrite
4. Sodium Hyaluronate Shows Promise In Treatment Of Shoulder Pain
5. Cadila Gets Tentative USFDA Nod For Pravastatin Sodium Tablets
6. Altered Sodium Channel Function Linked to Heart Failure
7. Low Blood Sodium When Born Linked to Long Term Sodium Intake
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Stroke Destroys Nearly 32, 000 Neurons In Just A Second!
10. New Technique Destroys Kidney Tumors By Freezing Them
11. New Hand Gel Destroys Bird Flu Virus
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... ... , ... The American College of Medical Informatics (ACMI) will present the 2017 ... Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is ... pioneer in the field of medical informatics, this prestigious award is presented to an ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... system that we intend to develop to enable prevention of a major side ... severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader ... a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were ... 11, 2017. , The annual award competition recognizes editorial and design excellence across a ...
(Date:10/12/2017)... , ... October 12, 2017 , ... On Saturday, October ... treadmill relay – Miles by Moonlight to raise money for the American Heart Association ... more. , Teams will work together to keep their treadmills moving for 5 ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 2017   Montrium , an industry leader ... the IQPC Trial Master Files & Inspection Readiness ... EastHORN Clinical Services has selected eTMF Connect ... management. EastHORN, a leading European contract research organization ... transparency to enable greater collaboration with sponsors, improve ...
(Date:9/22/2017)... Sept. 22, 2017  As the latest Obamacare repeal ... Bill Cassidy (R-LA) and Lindsey Graham ... the medical device industry is in an odd place. ... the 2.3% excise tax on medical device sales passed ... want covered patients, increased visits and hospital customers with ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., a ... today announced that it has been ranked #1 by its ... Book™ Rankings 2017 User Survey. ZirMed was recognized as ... large hospitals and medical centers over 200 beds and holds ... healthcare technology user survey history. ...
Breaking Medicine Technology: