Navigation Links
Smoking Linked to Lower Parkinson's Disease Risk

A new analysis of data from previous studies suggests that smokers are less likely to develop Parkinson's disease .

Several studies have suggested cigarette smoking appears to be associated with a reduced risk for developing Parkinson's disease and now an analysis by Beate Ritz, M.D., Ph.D., of the UCLA School of Public Health, Los Angeles, and colleagues has confirmed these suggestions.

As a part of their study the researchers pooled data from 11,809 individuals (2,816 individuals with Parkinson's disease and 8,993 controls of the same age and sex but without Parkinson's disease) involved in 11 studies conducted between 1960 and 2004.

They found that there is an inverse association between cigarette smoking and Parkinson's disease.

"Recent studies also suggested that Parkinson's disease risk is particularly low in active smokers with a long history of intense smoking; some even suggested dose-related risk reductions with increasing pack-years of smoking," the authors write.

"Our analyses confirmed prior reports of an inverse association between cigarette smoking and Parkinson's disease similar in size to those reported in a recent meta-analysis.

"We also showed that associations did not differ by sex or educational status. Although we found that current smokers and those who had continued to smoke to within five years of Parkinson's disease diagnosis exhibited the lowest risk, a decrease in risk (13 percent to 32 percent) was also observed in those who had quit smoking up to 25 years prior to Parkinson's disease diagnosis," the authors write

Other tobacco products also appeared to be protective - men who smoked pipes or cigars had a 54 percent lower risk. The number of chewing tobacco users was small, but there was a suggestion of reduced risk associated with this product.

The researchers found no association between smoking and Parkinson's disease risk in individuals older than 75. In addition, while the association was strong in white and Asian-American individuals, no association was observed in Hispanic or African-American participants.

"The biochemical basis for possible preventative effects of smoking, or of a substance delivered through cigarette smoke, is not well understood, but animal studies have indicated two possible mechanisms: chemical or biochemical processes may exist by which substances contained in cigarette smoke such as nicotine or carbon monoxide exert a protective effect and promote survival of dopaminergic neurons; or cigarette smoke alters the activity of metabolic enzymes or competes with other substrates for these enzymes and thereby alters the production of toxic endogenous (dopamine quinones) or exogenous (MPP+) metabolites," the authors write.

"Ultimately, only randomized intervention trials can confirm that some components in tobacco are truly neuroprotective, negating the possibility that a premorbid personality influences smoking behavior among those who later develop Parkinson's disease," they conclude.

The report appears in the July issue of Archives of Neurology, one of the JAMA/Archives journals.


'"/>




Related medicine news :

1. New hope on the Horizon for People Wishing to Quit Smoking
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Smoking a greater risk than HIV? Yes say health experts!!!!
4. Kick Smoking with Nicotine Drink
5. Smoking spreads Cancer
6. Prescription Drug - Helps People Stop Smoking
7. Quit Smoking
8. Smoking can depreciate intellegence
9. Smoking Delays Pregnancy
10. Smoking Linked To Low Infant Birth Weight
11. GlaxoSmithKline To Cultivate Non-Smoking Environment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... , ... "FCPX editors can now reveal their media with growing colorful split ... Austin - CEO of Pixel Film Studios. , ProSlice Color brings the split ... now reveal the media of their split screens with growing colorful panels. , ProSlice ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... 26, 2016 , ... PawPaws brand pet supplements owned by Whole ... enhance the health of felines. The formula is all-natural and is made from Chinese ... PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Bay Area Lyme Foundation , collaborating ... for Tick Borne Illness , Harvard Medical School ... Medicine, University of California, Berkeley, and the Veterans ... finalists of Lyme Innovation , the first ... scientists, clinicians, researchers, entrepreneurs, and investors from several ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, 2016 ... mobile pulmonary function testing company, is now able to perform sophisticated ... by ndd Medical Technologies , Inc. Patients ... hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients ... get any needed testing done in the comfort of her own ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: