Navigation Links
Smoking Cessation Therapy May be Harmful for ICU Patients

A common smoking cessation therapy used to help reduce adverse events associated with nicotine withdrawal may actually increase the risk of death for smokers admitted to// the intensive care unit (ICU). In a new study presented at CHEST 2006, the 72nd annual international scientific assembly of the American College of Chest Physicians (ACCP), researchers found that smokers admitted to the ICU who received nicotine replacement therapy (NRT) during their stay had a higher risk of death than smokers who did not receive NRT.

“In some critically ill patients, the development of nicotine withdrawal symptoms can worsen their prognosis. As a result, NRT is given to active smokers in the ICU to prevent nicotine withdrawal symptoms,” said lead researcher Amy Lee, MD, Mayo Clinic College of Medicine, Minneapolis, MN. “The hemodynamic effects of nicotine may lead to increased heart rate, systemic arterial blood pressure, and constriction of the coronary arteries. Although these potential adverse effects of NRT have not been shown to worsen the prognosis of healthy volunteers and patients with stable coronary artery disease, they may be detrimental in critically ill patients.”

Lee and colleagues examined the safety of NRT in the ICU by reviewing the medical records of 112 smoking patients admitted to the ICU who received NRT during their stay. Researchers compared patient outcomes between the NRT group and a control group. Among the patients who received NRT, 18 deaths (16.1%) occurred, compared with the 3 deaths (2.7%) in the control group. The hospital mortality rate was 21.4% for the NRT group, compared with 5.4% in the control group. Furthermore, when researchers controlled for severity of illness, NRT was found to be an independent risk factor for mortality (odds ratio 17.0).

There were no statistically significant differences in age, gender, ethnicity, and severity of illness measured by APACHE III prognostic model between the NRT and co ntrol groups. The median ICU length of stay for the NRT group was 24.4 (16.1 – 63.6) hours, compared with 22.6 (14.0 – 42.8) hours for the control group. The median hospital length of stay was 29.6 (18.3 – 127.1) hours, compared with 46.2 (19.8 – 117.3) hours for the control group.

“Although administering nicotine replacement therapy to smokers in the ICU is not a standard practice, some ICUs have nurse-driven protocols aimed at providing NRT for active smokers. We expect NRT to be more widely used in such ICUs,” said senior author Bekele Afessa, MD, FCCP, Mayo Clinic College of Medicine. Common signs of nicotine withdrawal include craving, irritability, depression, restlessness, and sleep disturbances. However, researchers caution that, because of other conditions that mimic nicotine withdrawal in the critically ill, to may be difficult to make an accurate diagnosis.

“Minimizing the effects of nicotine withdrawal in critically ill patients who smoke can present a significant challenge to the ICU team,” said Mark J. Rosen, MD, FCCP, President of the American College of Chest Physicians. “The findings of this study are intriguing and reinforce the need for additional research regarding the effects of nicotine replacement therapy on patients in the ICU.”

Source-Neswise
SRM
'"/>




Related medicine news :

1. New hope on the Horizon for People Wishing to Quit Smoking
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Smoking a greater risk than HIV? Yes say health experts!!!!
4. Kick Smoking with Nicotine Drink
5. Smoking spreads Cancer
6. Prescription Drug - Helps People Stop Smoking
7. Quit Smoking
8. Smoking can depreciate intellegence
9. Smoking Delays Pregnancy
10. Smoking Linked To Low Infant Birth Weight
11. GlaxoSmithKline To Cultivate Non-Smoking Environment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/10/2016)... ... 10, 2016 , ... United Benefit Advisors (UBA), the nation’s ... to its growing list of Partner Firms. S.S. Nesbitt is headquartered in ... Huntsville and in between. , Harnessing the experience and insights of the agency’s ...
(Date:2/10/2016)... ... 2016 , ... AHRA: The Association for Medical Imaging Management ... will serve as keynote speaker at the organization’s 2016 Spring Conference. Fox’s topic, ... effectively communicate with their own organizational staff and leadership. , “I am ...
(Date:2/10/2016)... Palm Beach, Florida (PRWEB) , ... February 10, ... ... & Country Club) announced that it has been awarded the prestigious Distinguished Emerald ... the World award program conducted by BoardRoom magazine, one of the most respected ...
(Date:2/10/2016)... ... February 10, 2016 , ... Workrite Ergonomics this week ... series of monitor mounts ever. , “Our goal was to develop a product ... install system that we have ever created.” said Darren Hulsey, Product Manager for Workrite ...
(Date:2/10/2016)... ... , ... A new leadership team for Mid-South Youth Camp, operated by Freed-Hardeman ... announcement Monday night, Feb. 8, prior to the evening session of the university’s 80th ... of GO! Camp, has been named director. Gayle McDonald, currently the assistant director of ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... 10, 2016 Urologix, the market leader for ... Benign Prostatic Hyperplasia (BPH), announces new private ownership and ... a medical device industry veteran of more than 20 ... Company.  Plymouth, Minn. ... ThermoTherapy™ and Prostiva® RF Therapy, will continue to be ...
(Date:2/10/2016)... -- A Worldwide Clinical Trials expert will present ... Park Plaza in London , 24-25 February ... future advances for late phase research on Wednesday, 24 Feb ... associate director of project management at Worldwide, will focus on ... and standards in late phase research. --> ...
(Date:2/10/2016)... DIEGO , Feb. 10, 2016  Visage ... Pro Medicus Ltd. (ASX: PME), has announced that the ... of Florida (UF) have selected the Visage 7 ... viewer of the Emergent/Critical Care Imaging SIMulation (SIM). ... in Diagnostic Imaging Program (WIDI), a multi-faceted and ...
Breaking Medicine Technology: