Navigation Links
Smokeless Cannabis Delivery Device Found Efficient and Less Toxic

A smokeless cannabis-vaporizing device delivers the same level of active therapeutic chemical and produces the same biological effect as smoking cannabis , but without the harmful toxins, according to UCSF researchers.

Results of a UCSF study, which focuses on delivery of the active ingredient delta-9-tertrahydrocannibinol, or THC, are reported in the online issue of the journal "Clinical Pharmacology and Therapeutics."

"We showed in a recent paper in the journal 'Neurology' that smoked cannabis can alleviate the chronic pain caused by HIV-related neuropathy, but a concern was expressed that smoking cannabis was not safe. This study demonstrates an alternative method that gives patients the same effects and allows controlled dosing but without inhalation of the toxic products in smoke," said study lead author Donald I. Abrams, MD, UCSF professor of clinical medicine.

The research team looked at the effectiveness of a device that heats cannabis to a temperature between 180 and 200 degrees C, just short of combustion, which occurs at 230 degrees C. Eighteen individuals were enrolled as inpatients for six days under supervision in the General Clinical Research Center at San Francisco General Hospital Medical Center.

Under the study protocol, the participants received on different days three different strengths of cannabis by two delivery methods-smoking or vaporization-three times a day.

Plasma concentrations of THC were measured along with the exhaled levels of carbon monoxide, or CO. A toxic gas, CO served as a marker for the many other combustion-generated toxins inhaled when smoking.

The plasma concentrations of THC were comparable at all strengths of cannabis between smoking and vaporization. Smoking increased CO levels as expected, but there was little or no increase in CO levels after inhaling from the vaporizer, according to Abrams.

"Using CO as an indicator, t here was virtually no exposure to harmful combustion products using the vaporizing device. Since it replicates smoking's efficiency at producing the desired THC effect using smaller amounts of the active ingredient as opposed to pill forms, this device has great potential for improving the therapeutic utility of THC," said study co-author Neal L. Benowitz, MD, UCSF professor of medicine, psychiatry and biopharmaceutical sciences. He added that pills tend to provide patients with more THC than they need for optimal therapeutic effect and increase side effects.

Patients rated the "high" they experienced from both smoking and vaporization and there was no difference between the two methods by patient self-report of the effect, according to study findings. In addition, patients were asked which method they preferred.

"By a significant majority, patients preferred vaporization to smoking, choosing the route of delivery with the fewest side effects and greatest efficiency," said Benowitz.


'"/>




Related medicine news :

1. Cannabis for pain
2. Cannabis to be tested to help patients with respiratory diseases
3. Cannabis exerts protective effect against cancer
4. Relief For British MS Patients: Cannabis-Based Oral Spray
5. Alcohol And Drug Abuse (Cannabis) Leading Causes For Road Traffic Accidents
6. Government May Downgrade Cannabis
7. Can Cannabis Cause Madness?
8. Campaigners Say No To Cannabis Reclassification
9. No Increased Schizophrenia Risk With Use Of Cannabis
10. Tackling of Cannabis Addiction
11. Australia Set To Implement A national Strategy Tackle Cannabis Abuse
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2017)... ... ... Chocolate Biscuit”: a biographical account following a man who went on to support his country ... Ivey, born in Lynn Haven, Florida and at the age of 5, his family moved ... he joined the Navy and got married right out of boot camp. , He ...
(Date:1/20/2017)... ... , ... “Christmas in Suffolk”: a story of love, secrets, and mystery. ... Lafayette, Indiana where she works in a daycare and looks for inspiration in the ... Christian Faith Publishing, Sara Seymour’s new book is an adventure of love and secrets. ...
(Date:1/20/2017)... ... ... Land of More and More”: a brilliant story for children and adults alike ... achievable answer. “The Land of More and More” is the creation of published author, ... where he works with the children’s ministry department. , Michael says that he ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... Aerolib Learning Management System: an On-demand E-learning system for Clinical and Regulatory ... Administration that is based on Aerolib`s successful education methodology of Disease Specific ...
(Date:1/19/2017)... ... January 19, 2017 , ... With the cold weather here, many people will have to ... efficient when clearing large amounts of snow, but they can be dangerous when used incorrectly. ... Product Safety Commission for the proper use of snow blowers:, , ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... 2017 Avillion LLP, a co-developer and financier ... Weinberg , MD MBA as Chief Medical Officer. Dr Weinberg will ... . ... Weinberg has spent more than 17 years as a pharmaceutical and ... micro-cap biotech. Over the course of his career, he has interfaced ...
(Date:1/19/2017)... , Jan. 19, 2017 Report Details ... Devices Market? Which areas are going to grow at ... revenues to 2026, assessing data, trends, opportunities and prospects. ... graphs. Discover the most lucrative areas in the industry ... you assess forecasted sales across the all the major ...
(Date:1/19/2017)... -- Conference Call and Webcast to Follow Vanda Pharmaceuticals ... release results for the fourth quarter of 2016 on Wednesday, February ... ... 4:30 PM ET on Wednesday, February 15, 2017, during which management ... and other corporate activities. To participate in the conference call, please ...
Breaking Medicine Technology: