Navigation Links
Smell Decoding System In Brain –Research Find

Researchers of the Duke University Medical Center have found from animal studies that the brain don’t receive fragnance as a single object //, but perceives it, divides it into categories and send to brain's olfactory system (smarter sections) to combine these compounds into a recognizable scent.

Humans may rely on the same smell decoding system, because mice and men have similar brain structures for scent, including an olfactory bulb, the researchers said.

"We wanted to understand how the brain puts together scent signals to make an odor picture. We discovered the whole is the sum of its parts," said Da Yu Lin, Ph.D., who conducted the research as a graduate student studying with neurobiologist Lawrence Katz, Ph.D., a Howard Hughes Medical Institute investigator at Duke. Katz died in November 2005.

The research appears June 16, 2006, in the journal Neuron. The study was supported by the National Institutes of Health, the Howard Hughes Medical Institute and the Ruth K. Broad Biomedical Research Foundation.

Scientists have long debated how the brain makes order out of the hundreds of volatile chemical compounds that assault the nose. Is the brain's odor code redundant, with single cells responding to multiple components in the smell of a freshly baked cookie? Or does the brain process each scent component like a jigsaw puzzle piece, assembling the signals until it recognizes the picture is a cookie?

To find answers, the Duke researchers exposed mice to different odors and measured response of neurons across the olfactory bulb with intrinsic signal imaging. The imaging technique maps brain activity by detecting changes in reflected light from the brain with a sensitive camera.

To start, the researchers separated and identified the volatile compounds in each odor with gas chromatography. "A complex mixture like urine has at least a hundred separate compounds in it," Lin said. They analyzed scents as diverse as peanut butter, coffee and fresh bobcat urine shipped to the laboratory on dry ice.

The researchers then exposed the mice to the original odor and its individual compounds. "We found that glomeruli, the functional units of the olfactory bulb, act as detectors for individual compounds," Lin said. "There are no single detectors for complete smells."

Thus, to distinguish different scents, the brain must integrate the signals of multiple chemical components into an odor "picture." The researchers suspect that this integration doesn't happen in the olfactory bulb. Instead, the bulb likely passes the data to more advanced brain structures where it is assembled and recognized as a specific scent.

Understanding how the olfactory system works in mice may also provide broader insights into human perception, said Stephen Shea, Ph.D., a Duke University Medical Center research associate who participated in the study. Perception relies on combining multiple components, whether the input is smell, sight or sound. Shea suggested that probing the olfactory system could help scientists better understand, for example, how the various biological and neurological components underlying perception formed and evolved.

(Source: Eurekalert)
'"/>




Related medicine news :

1. Lack of Smell And Its Potential Risks
2. More About The Coffee Bean Than Just A Heavenly Taste and Smell
3. Researchers Discover How We Differentiate Smells
4. Decoding the Fungi Genome Will Save Millions of Lives.
5. Decoding the Medicare Code
6. Early Warning System For Breast Cancer
7. Gene connected to Multi-System disorder discovered
8. Reviving the Immune System
9. Painkilling Patch As Effective As Intravenous Delivery Systems
10. Wrestling found To Be Good for the Immune System
11. Computer System To Predict Deep Vein Thrombosis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... is proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon ... beautiful women in the world, and the most handsome men, look naturally attractive. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Frederick area economy by obtaining investment capital for emerging technology companies. ... years that have already resulted in more than a million dollars of capital ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s ... June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... helping service members that have been wounded in battle and their families. Venture Construction ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today that ... Supplier Horizon Award . One of ... was recognized for its support of Premier members through ... clinical excellence, and commitment to lower costs. ... this recognition of our outstanding customer service from Premier," ...
(Date:6/23/2016)... Research and Markets has announced the addition ... States, China, Japan, Brazil, United Kingdom, Germany, France, Italy, ... Surgical Procedure Volumes: Global ... surgical procedure volume data in a geographic context. The ... of growth drivers and inhibitors, including world population growth, ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... rough waters, but it continues to present great opportunities ... featured companies for today: Intrexon Corp. (NYSE: ... ), Arena Pharmaceuticals Inc. (NASDAQ: ARNA ), ... Learn more about these stocks and receive your complimentary ...
Breaking Medicine Technology: