Navigation Links
Slowing the Racing Heart

Researchers at the University of Illinois at Chicago explain in the May 11 issue of Circulation Research how an enzyme acts on the heart's pacemaker to slow the rapid beating of the heart's "fight-or-flight" reaction to adrenaline.

A single cell in the upper right chamber is responsible for setting the pace of the beating heart, triggering its neighbor cells to beat. In the human heart, one cell - the pacemaker cell - beats faster or slower to induce a rhythmic heartbeat that varies to increase or decrease the blood flow to the body as we eat, sleep or exercise.

"Disturbances of pacemaker control are common in heart diseases. When the heartbeat becomes non-rhythmic and chaotic, it can result in fatal arrhythmias and stroke," said R. John Solaro, UIC distinguished university professor and principal investigator of the study.

Current treatment of arrhythmia requires destruction of tissue surrounding a chaotic pacemaker, followed by insertion of a mechanical pacemaker that can regulate the heartbeat.

"Understanding the molecular regulation of the heart's pacemaker opens the possibility of less drastic treatment options, including drug interventions," said Solaro, who is also director of the center for cardiovascular research and head of physiology and biophysics at UIC.

Solaro worked with Yunbo Ke, UIC research assistant professor of physiology and biophysics and first author of the paper, and colleagues in England at Oxford and Manchester on characterizing and isolating the pacemaker cell.

The UIC researchers demonstrated that an enzyme called Pak 1, present in high concentrations in the heart, signals depression in the action of adrenaline and adrenaline-like chemicals on the pacemaker cell, playing an important role in slowing down the heart rate.

"The enzyme works through calcium and potassium channels that we know to be key players in the generation and regulati
'"/>




Page: 1 2

Related medicine news :

1. Slowing Down The Progression Of Alzheimer’s Disease
2. Slowing Down The Progression Of Tumour Cells With Omega-6 Fatty Acids
3. Slowing Cartilage Loss In Arthritis With Fruit Extracts
4. NHS Food Slowing Patient Recovery
5. New Drugs Shows Promise in Slowing the Progression of Prostate Cancer
6. Slowing the Racing Heart
7. One in Three Heart Attack Patients Have No Chest Pains
8. Epileptic Seizures Can Be Duec to Heart Problem
9. Bypass Heart Surgery Performed Without General Anesthesia
10. New CPR Guidelines issued by Heart Association
11. White Cells Count Can Predict Heart Attack Death Risk
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Slowing the Racing Heart

(Date:8/20/2014)... The Board of Directors of top ... is pleased to announce the expansion of its ... and the surrounding region. In support of this ... AIA has relocated to the firm’s office in Shanghai, ... and design and to better support regional clients. ...
(Date:8/20/2014)... the most persistent and deadliest infectious diseases in the ... , Scientists who study tuberculosis have long debated its ... humans in Africa to seals and sea lions that ... to Native people there before Europeans landed on the ... as a Source of New World Human Tuberculosis," was ...
(Date:8/20/2014)... through fast-moving waters may be at risk, suggests new ... salmon encounter turbulent, fast-moving water such as rapids ... upstream using a behaviour known as "burst swimming" that ... sockeye passed through extremely fast-moving water, we started to ... spawning grounds," said Nicholas Burnett, a research biologist at ...
(Date:8/20/2014)... 20, 2014 As concerns regarding the ... morcellators ( http://www.injurybeacon.com/power-morcellator/ ) in gynecological surgery continue ... Senators from New York are urging the U.S. Food ... the devices. In a letter dated August 19th, Sens. ... the agency to seriously consider the testimony given during ...
(Date:8/20/2014)... NY (August 20, 2014) Research from Columbia University ... role in stomach cancer growth and that blocking nerve ... effective treatment for the disease. The study was conducted ... collaboration with Duan Chen, MD, PhD, in Norway and ... Medicine . , "Scientists have long observed that human ...
Breaking Medicine News(10 mins):Health News:Perkins Eastman Expands Presence in China 2Health News:Perkins Eastman Expands Presence in China 3Health News:New research shows seals and sea lions likely spread tuberculosis to humans 2Health News:New research shows seals and sea lions likely spread tuberculosis to humans 3Health News:Salmon forced to 'sprint' less likely to survive migration 2Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 2Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 3Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 4Health News:Severing nerves may shrink stomach cancers: Botox injections slow growth of tumors in mice 2
... with current devices , , MONDAY, Jan. 21 (HealthDay News) ... for overcoming the major problems with these tubes that ... Italian researchers report. , The new stent is not ... use, but with a special polymer designed to prevent ...
... in 2007, KNOXVILLE, Tenn., Jan. 21 ... clinical outsourcing, announced today,that it has initiated ... December 2007 and January 2008. These contracts ... medicine programs in seven,states., TeamHealth will ...
... WASHINGTON, Jan. 21 Senator Sam Brownback,and Rep. ... for Life, on,Tuesday, January 22, 2008. The conference ... College Professor Hadley P.,Arkes, Eric Scheidler, Michael Illions, ... live from Family Research Council,s headquarters., Senator ...
... DIEGO, Jan. 21 AMN Healthcare Services,Inc. (NYSE: ... United,States, will host its quarterly conference call to discuss ... 2008, at 5:00 p.m. Eastern,Time. The company expects to ... 2008 at approximately 4:00 p.m. Eastern Time., A ...
... Biosciences,(Nasdaq: MATK ) announced today that life,sDHA(TM), its ... heart health, is now available to,Australian consumers in Pocket ... is the largest juice and smoothie chain in the,Southern ... Pocket Rocket Juice provides,more than 100 percent of Australia,s ...
... kick butts, SAN DIEGO, Jan. 21 RealAge.com, ... a new program to guide and,support nicotine-free wannabes as ... Stop Smoking Center launched today. The center is packed,with ... MD, a,founder of RealAge and coauthor of YOU: Staying ...
Cached Medicine News:Health News:'Drug-Free' Stent Coating Shows Promise 2Health News:TeamHealth Announces Eight New Clinical Outsourcing Contracts 2Health News:Senator Sam Brownback and Rep. Chris Smith to Speak at Blogs for Life 2Health News:AMN Healthcare Services to Host 2007 Fourth Quarter & Year End Earnings Conference Call on Tuesday, February 26, 2008 2Health News:Pocket Rocket Juice from Australia's Boost Juice Features 700 mg of Martek's life'sDHA(TM) 2Health News:Pocket Rocket Juice from Australia's Boost Juice Features 700 mg of Martek's life'sDHA(TM) 3Health News:RealAge Challenges and Cheers Smoke-Free Wannabes in 2008 2
(Date:8/20/2014)...   Easy Breathe , the fastest growing online sleep ... " - has received more than 4.5 million unique page views ... thrilled that so many people are finding our blog and reading ... "We,re committed to making sleep apnea more widely known and hope ... sleep apnea news , troubleshooting advice , and ...
(Date:8/20/2014)... NEW YORK , Aug. 20, 2014 /PRNewswire/ ... new market research report is available in its ... Electronic Medical Records http://www.reportlinker.com/p0833392/EMR-2014-The-Market-for-Electronic-Medical-Records.html ... fast-changing market for electronic medical records (EMR) for ... a comprehensive report of our findings. Our report ...
(Date:8/20/2014)... 20, 2014 Phase I Trial ... US  KalVista Pharmaceuticals ("KalVista"), an ophthalmology company ... announces that it has begun a Phase I, First ... KVD001, for the treatment of DME. The study,s Principal ... Eye Institute, Joslin Diabetes Center; Harvard Medical School Department ...
Breaking Medicine Technology:Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4EMR 2014: The Market for Electronic Medical Records 2EMR 2014: The Market for Electronic Medical Records 3EMR 2014: The Market for Electronic Medical Records 4EMR 2014: The Market for Electronic Medical Records 5EMR 2014: The Market for Electronic Medical Records 6EMR 2014: The Market for Electronic Medical Records 7EMR 2014: The Market for Electronic Medical Records 8KalVista Pharmaceuticals Announces Start of Clinical Development for Novel Treatment for Diabetic Macular Edema 2KalVista Pharmaceuticals Announces Start of Clinical Development for Novel Treatment for Diabetic Macular Edema 3KalVista Pharmaceuticals Announces Start of Clinical Development for Novel Treatment for Diabetic Macular Edema 4
... Galleon Pharmaceuticals, a leader in the pharmaceutical treatment of ... has elected Thomas J. Dietz, Ph.D., as the company,s ... Holdings, LLC, a diversified financial-holdings and services company.   ... then CEO and a director of Pacific Growth Equities, ...
... Reportlinker.com announces that a new market ... Medical Imaging Markets: Contrast ... The application and versatility of ... in significance as the population ages and ...
Cached Medicine Technology:Thomas Dietz, Ph.D., Elected Chairman of Galleon Pharmaceuticals 2Medical Imaging Markets: Contrast Agents 2Medical Imaging Markets: Contrast Agents 3Medical Imaging Markets: Contrast Agents 4Medical Imaging Markets: Contrast Agents 5Medical Imaging Markets: Contrast Agents 6
... enzyme linked immunosorbent assay ... and semiquantitation of anti-glomerular ... in human serum. The ... can be used as ...
An indirect immunofluorescence (IFA) antibody test for the detection and semiquantitation of anti-glomerular basement membrane (GBM) antibodies in human serum. Slide Detail: 6-well Monkey Kidney Subs...
Rheumatoid factor screening...
An enzyme linked immunosorbant assay (ELISA) for the detection and quantitation of Rheumatoid Factor (RF) IgA isotype in human serum....
Medicine Products: