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Sling Surgery Better Than Burch for Treating Stress Incontinence in Women

br> This higher bar may account for lower success rates in SISTEr than in earlier trials, but it also "establishes a template for conducting surgical trials for urinary incontinence and for other urological conditions," said John W. Kusek, Ph.D., co-director of kidney and urology trials at NIDDK.

NIH's National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Child Health and Human Development and Office of Research on Women's Health funded the Urinary Incontinence Treatment Network, a group of nine clinical centers and a biostatistical center, to conduct a series of rigorous, long-term trials of common incontinence therapies.

Urinary incontinence is a common and costly condition that reduces quality of life for American women. NIDDK's Urologic Diseases in America project reports that up to three-fourths of women have some degree of incontinence, and the direct cost of incontinence for women was $12.4 billion in 1995.

SISTEr is the first trial completed by UITN, with two other studies in the wings. Results of the second trial, the Behavior Enhances Drug Reduction of Incontinence (BE-DRI), for urge incontinence, are expected later this year. BE-DRI asked 307 women to make changes such as emptying the bladder on a regular schedule and to practice Kegel exercises to strengthen pelvic muscles to learn if these common treatments would allow women to stop drug therapy and maintain the same degree of bladder control.


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