Navigation Links
Sleep Disorder Linked to Heart Failure Patient Deaths

Heart failure patients with untreated sleep apnea are more likely to die than those without this sleep disorder, says a study//.

The study followed 164 patients with heart failure for more than seven years, and found that those with obstructive sleep apnea (OSA) had double the death rate of those patients who did not have sleep apnea. Of the 37 patients with untreated OSA, the death rate was 24% in contrast to 12% for the 113 patients with no sleep apnea.

Obstructive sleep apnea is common in patients with heart failure, and contributes to increased blood pressure, heart rate and other cardiac disturbances. This is the first time that the effect of obstructive sleep apnea on mortality rates of heart failure patients has been studied and reported.

“The vast majority of heart failure patients across North America are not being assessed for the diagnosis of sleep apnea and, as a result, are not being treated for it. Our data says that many of these patients need to be treated for this disorder and that this will have a significant impact on their survival,” said Dr. Douglas Bradley, Head of the Sleep Research Laboratories at Toronto General Hospital, Toronto Rehabilitation Institute, and Mount Sinai Hospital, and Director of the University of Toronto Center for Sleep Medicine and Circadian Biology.

More than 500,000 Canadians are treated for heart failure every year, with an additional 50,000 new cases every year. In the most severely affected, the one-year death rate can be as high as 40%, and it is the leading cause of hospital admission for individuals above the age of 65. Although drug therapy has reduced death rates in the last five to 10 years, and participation in a cardiac rehabilitation program can improve a patient’s quality of life by increasing stamina and decreasing shortness of breath, heart transplantation is the only long-term treatment for patients suffering from end-stage heart failure. However, because there is a severe shortage of donor hearts for transplantation, scientists are looking for alternate therapies. One such approach, suggested by the present study, is treatment of OSA in heart failure patients.

Obstructive sleep apnea occurs when a person stops breathing during sleep at least 15 to 20 times an hour. These recurrent interruptions in breathing deprive the brain of oxygen and activate the sympathetic nervous system, causing increases in blood pressure, heart rate and other disturbances. This, in turn, contributes to the progression of heart failure and mortality.

However, as Dr. Bradley pointed out, most heart failure patients don’t have the usual symptoms linked to OSA, which include: headache in the morning; loud snoring, restless sleep, or daytime sleepiness. “Sleep studies for heart failure patients are crucial in determining whether they have obstructive sleep apnea. Since the risk of death for these patients is significant, we need to be more vigilant in pursuing the diagnosis of obstructive sleep apnea in these patients,” he said.

This research will influence how we investigate and treat patients with heart failure, said Dr. John Parker, Head of Cardiology at the Peter Munk Cardiac Centre, University Health Network and Mount Sinai Hospital, adding that “treating sleep apnea in these patients has become as routine as implanting pacemakers or using defibrillators.”

Patients for the study were recruited from the Heart Failure Clinic of the Mount Sinai Hospital and the sleep studies were performed in sleep laboratories at Toronto General Hospital and the Toronto Rehabilitation Institute. In order to clearly determine the effect of sleep apnea, the characteristics of all the heart failure patients in the two groups were generally the same, including age, gender, severity of symptoms, medications, weight, and diabetes.

The research also suggests that there is a strong trend to a reduced death rate for the patients with OSA who were treated with a device called continuous positive airway pressure (CPAP). The device applies air pressure via a mask placed over the nose during sleep. The continuous air pressure flows through the nose into the throat, propping it open and preventing it from collapsing during sleep. This allows a person to breathe without interruptions.

There were no deaths in the groups of 14 heart failure patients who had OSA and who were also treated with the CPAP device for at least three months. However, of the 37 patients with untreated sleep apnea, nine patients (24%) died. Patients in each group were similar in symptom severity, heart failure therapy and other factors.

Source-NewswiseSRM/B
'"/>




Related medicine news :

1. Sleep apnoea increases post-operative risks
2. Sleep, snoring....stroke
3. Sleeping sickness - a silent killer
4. Deep Sleep Doesnt Increase Memory
5. Sleepwalking has genetic roots
6. Sleepy drivers increase road death toll
7. Sleep apnoea linked to surgical risks
8. Sleep disorders can have anomalistic sexual acts
9. Sleepwalking linked to a gene
10. Sleep Apnea Linked to Bed-Wetting in Kids
11. Race Affects Sleep in Children
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/12/2016)... ... February 12, 2016 , ... According to an ... beginning to account for a significant portion of hernia repairs throughout the United States. ... Beverly Hills Hernia Center notes that this trend has not only been expected, but ...
(Date:2/12/2016)... ... February 12, 2016 , ... Mystic Buddha Publishing House presents Valentine’s ... Buddha, the biography of Rama - Dr. Frederick Lenz. , According to ... of a Buddhist teacher for teaching and helping others. Valentine’s Day celebrates love ...
(Date:2/12/2016)... ... 12, 2016 , ... The law firm of Morrow, Morrow, Ryan & Bassett ... of these scholarships is to encourage applicants to pursue a degree in their field ... two parishes. , “We have available jobs in St. Landry and Evangeline Parishes ...
(Date:2/12/2016)... , ... February 12, 2016 ... ... today announced a new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the advanced ... will recruit top students from U.S. universities who will draw from Siemens’ ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ... funding innovative lymphoma research and serving the lymphoma community through a comprehensive series ... of South Florida’s philanthropic community at its 10th anniversary Fashion Luncheon on Monday, ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... CHAPEL HILL, N.C. , Feb. 12, 2016  Clinical Affairs ... their clinical presence in emerging areas of the world. While some ... regions, others lag in their clinical activity in countries such as ... China and India ... approvals to market products in those countries. --> ...
(Date:2/12/2016)... , Feb. 12, 2016   National Community Pharmacists ... RPh, MBA issued the following statement today in response ... by the Centers for Medicare & Medicaid Services ... NCPA, beneficiary advocates and others: patient advocacy ... are still reviewing the full CMS analysis. Our initial ...
(Date:2/12/2016)...  This month,s issue of the Journal of ... in-depth look at various causes and consequences associated with rising health ... which has generated significant public outrage and calls for ... E. Happe , PharmD, MPH. --> JMCP ... --> In 2014 prescription drug spending in ...
Breaking Medicine Technology: