Navigation Links
Skin-Destroying Ulcer Appears in NSW as New Treatment Guidelines Emerge

Infectious disease specialists have revealed the skin- and flesh-destroying Bairnsdale ulcer has struck a man in NSW for the first time, as experts publish new recommendations for treating the tropical infection. //

Also known as the Buruli or Daintree ulcer, Bairnsdale ulcers are caused by Mycobacterium ulcerans infection, and result in the destruction of skin, soft tissue, and sometimes bone.

Associate Professor Paul Johnson, Deputy Director of the Infectious Diseases Department of Austin Health, in Melbourne, and colleagues have used the Medical Journal of Australia to caution GPs and other doctors to look out for the infection in NSW.

M. ulcerans infection was first described in Australia in coastal Victoria (Bairnsdale) in 1948 and since then has been found in central coastal Queensland and the Northern Territory.

Now, Assoc Prof Johnson and colleagues have identified the first known case believed to have originated in NSW.

“Australian primary care clinicians need to be aware that Bairnsdale ulcer may occur in NSW, to ensure early diagnosis and treatment to minimise disability,” he said.

The finding came as Australian plastic surgeons, GPs, laboratory scientists, pathologists, infectious disease physicians and public health experts collaborated to set down new consensus recommendations for the treatment and prevention of M. ulcerans infection.

Assoc Prof Johnson said the recommendations state that antibiotics and surgery are recommended for large ulcers, while smaller ulcers with clear margins can be treated with surgery alone.

The reason for outbreaks and mode of transmission are not yet known, but Assoc Prof Johnson said in endemic areas, direct exposure to the environment and to mosquitos are risk factors for contracting the infection.

“Wearing protective clothing and insect repellent appears protective,” he said.

“Future research should focus on what determines why a particular area becomes endemic.”

In the same issue of the MJA, Dr Daniel O’Brien, an infectious disease specialist at Barwon Health in Geelong, and colleagues said that treating the ulcers with surgery alone failed to eradicate the infection for one in four patients.

However after studying the treatment outcomes in a case series of 40 people in south-eastern Australia, they found that treating the initial ulcers with a combination of antibiotics for up to three months, as well as surgery, eradicated the infection in all patients.

“The combination of (the antibiotics) rifampicin and ciprofloxacin seems promising, and has the potential to provide an easily accessible, relatively well tolerated and inexpensive oral antibiotic treatment that can result in a significant reduction in ... morbidity and cost,” Dr O’Brien said.

In a related editorial, World Health Organisation tropical disease control officer Dr Kingsley Asiedu, and London-based infectious disease physician Dr Mark Wansbrough-Jones, said further research is needed into the treatment, diagnosis, and transmission of Buruli ulcer.

The disease is most common in Africa, they said, where patients cannot readily access or afford surgery.

“More work is needed to develop an ideal treatment strategy, in both developing countries and more sophisticated medical settings,” Dr Asiedu said.


Related medicine news :

1. Ulcer Surgery connected to danger of Pancreatic Cancer
2. Ulcer causing bug found in stored food
3. Drug Effective for Diabetic Foot Ulcers
4. Prevention Of Recurrent Leg Ulcers
5. Diabetic Ulcers A Probable Cause Of Depression
6. Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
7. Nobel For Ulcer-Defying Aussie Scientists
8. Bifidogenic Growth Stimulator: A Non-Toxic Way To Treat Ulcerative Colitis
9. Concerns About Popular Anti-Ulcer Pill Used For Inducing Labor
10. Novel Treatment Method Directed At Ulcer-Causing Bacteria Deemed A Success
11. Stubborn Ulcerative Colitis Responds to Arthritis Drug
Post Your Comments:

(Date:11/27/2015)... ... 2015 , ... The print component of “Supporting Our Caregivers” ... New York, Minneapolis, South Florida, with a circulation of approximately 250,000 copies and ... vast social media strategy and across a network of top news sites and ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... A simply ... Jones, is an interesting show that delves into an array of issues that are ... that could benefit from open dialogue, this show is changing the subjects consumers focus ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... Dr. ... Medical Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at St., ... observed that both STEMI and Sepsis conditions present in similar ways and require time-critical ...
(Date:11/26/2015)... ... November 26, 2015 , ... CognisantMD and Cambridge ... imaging in the Waterloo region. Using the Ocean Platform, family physicians can now ... their electronic medical record (EMR) without the need for redundant patient entry or ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... opinion process, participated in the 61st annual Employee Benefits Conference. The Employee Benefits ... place Sunday, November 8th through Wednesday, November 11th, 2015. The conference was held ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... Nov. 26, 2015  The total global healthcare industry is ... 2015-2016. Latin America has the highest ... (excluding Japan ), is second with growth ... to face increased healthcare expenditure. In 2013-2014, total government funded ... 43.5% in 2008-2009 to 41.2% in 2013-2014. In real terms, ...
(Date:11/25/2015)... , Nov. 25, 2015 AAIPharma Services ... investment of at least $15.8  Million to expand ... Wilmington, NC . The expansion will provide ... meet the growing demands of the pharmaceutical and ... site expansion will provide up to 40,000 square ...
(Date:11/25/2015)... 2015 Kitov Pharma ceuticals ... a biopharmaceutical company focused on the development of therapeutic ... today announced the closing of its previously announced underwritten ... ), each representing 20 ordinary shares of the Company, ... ADSs and warrants were issued in a fixed combination ...
Breaking Medicine Technology: