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Simulated Heart Tissue Enhances Understanding of Arrhythmias And Defibrillator Failure

e charged with electrical activity and attempts were made to curb it with pace-setting pulses. The team found that the pulses managed to arrest the wave in 80% of cases, while in the remaining cases a single wave multiplied into many waves that continued to catalyze the cardiac cells at a fast rate. In 20% of the cases, the purpose of actually ceasing the wave did not happen; in contrast it actually worsened the condition. This estimation almost matches the frequency of similar occurrences in patients with implanted defibrillators.

ICD devices render a potent shock when fast pulses mobilize tachycardia. Continued study of the engineered tissues could reveal further regarding better methods to arrest arrhythmias. The results have amply suggested the efficacy of using engineered tissue in studying the complex electrophysiological characteristics of the heart, according to Bursac. This would certainly hold the key to progressive drug and gene therapies purported to stabilize heart rhythms.

Source: Eureka Alert
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