Navigation Links
Simple Chemical Reaction may Help Early Disease Diagnosis

A new joint study has shown that using a simple chemical reaction might help detect important molecules in blood and urine.

The technique is effective as it increases the visibility of markers for some genetically caused metabolic disorders up to 100 times when detected through nuclear magnetic resonance spectroscopy equipment.

The study was conducted by a team of researchers led by Daniel Raftery and Bryan Hainline at Purdue University and Indiana University School of Medicine.

As part of the study, researchers used a method of analysis, called metabolomics, which involves the simultaneous analysis of multiple small molecules, or metabolites, which occur in fluids and tissues in the body.

The presence of a particular metabolite, grouping of metabolites or ratio of metabolites can indicate a response to biological stress or a specific disease state.

"The metabolic profile in biofluids, such as blood and urine, provides a snapshot of ongoing biological processes in the human body," Raftery said.

The researchers used nuclear magnetic resonance spectroscopy, a cousin of magnetic resonance imaging to detect hydrogen or carbon atoms to provide insight into the metabolites present and the visibility of certain type of metabolites, amino acids, by chemically tagging the molecules of interest so that they were more easily visible.

"We added a chemical that reacts with the amino acids and similar metabolites and forms a tag that can be seen through nuclear magnetic resonance. The tag actually is an easily identifiable isotope, in this case a carbon atom that is heavier than the standard carbon atom. Because we can easily detect this isotope, it causes these tagged metabolites to effectively pop out against the background of all of the others, Raftery said.

The findings of the study were published in the July issue of the Proceedings of the National Academy of Sc iences.


'"/>




Related medicine news :

1. Long-Term Survival can be Predicted by a Simple Lung Test
2. Simple Therapy
3. Simple Stroke Prevention is Best
4. Few Simple Steps to Lower The Incidence Of SIDS
5. A Simple Blood Test Can Predict Gum Disease
6. A Simple Exercise Can Uncover Undiagnosed Asthma
7. Simple Exercises Might Help Vertigo
8. Simple Steps To Help Fight Asthma
9. Simple Urine Test Can Help To Monitor Disfiguring Birthmarks
10. Revolutionary Simple Pregnancy Blood Test Can Save Both Mother And Child
11. Simple Procedural Improvements Can Improve Care Of Stroke Patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... ... August 18, 2017 , ... August 18, ... & Hearing,” advocating for active, healthy lifestyles and highlighting the importance of proactive ... with hearing impairments and shares the latest innovations in hearing aid technology. ...
(Date:8/18/2017)... ... , ... The Dawn Johnson Insurance Group, a Missouri-based insurance and financial planning ... support for efforts to educate the local population on cancer realities while attracting donations ... , Each day in America, roughly 4,600 new cases of cancer are diagnosed ...
(Date:8/18/2017)... ... August 18, 2017 , ... Moore Insurance, ... communities in east Texas, is launching a regional charity effort to provide publicity ... 1991, the Pediatric Brain Tumor Foundation (PBTF) has raised nearly $30 million in ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... firm that serves residential and commercial clients in the greater Houston region, is ... community support for the fight against cancer. , Founded by Tony and Amber ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... practitioners specializing in bioidentical hormone replacement therapy and integrative medicine, has become a ... conditions of aging, such as menopause, andropause, thyroid disorder and adrenal insufficiencies. ...
Breaking Medicine News(10 mins):
(Date:8/4/2017)... 2017 The search for test results that ... consult has long been the goal of healthcare providers ... of the largest meeting of lab professionals and IVD ... research firm Kalorama Information.  The firm said scores of ... related supplies and software were at the American Association ...
(Date:8/2/2017)... 2, 2017  Life Flight Network and PeaceHealth Oregon Network ... patient care and operational efficiency for patients at hospitals in ... Cottage Grove , and Florence, ... and Life Flight Network work collaboratively to move patients who ... when a time sensitive emergency exists. ...
(Date:7/31/2017)... Surgical, developer of ground breaking surgical navigation technologies, announced today ... support its strategic sales plan in Maryland ... Surgical has entered into an exclusive sales representative agreement with ... those markets. ... Spartan Medical Purchases 7D Surgical Technology ...
Breaking Medicine Technology: