Navigation Links
Simple Chemical Reaction may Help Early Disease Diagnosis

A new joint study has shown that using a simple chemical reaction might help detect important molecules in blood and urine.

The technique is effective as it increases the visibility of markers for some genetically caused metabolic disorders up to 100 times when detected through nuclear magnetic resonance spectroscopy equipment.

The study was conducted by a team of researchers led by Daniel Raftery and Bryan Hainline at Purdue University and Indiana University School of Medicine.

As part of the study, researchers used a method of analysis, called metabolomics, which involves the simultaneous analysis of multiple small molecules, or metabolites, which occur in fluids and tissues in the body.

The presence of a particular metabolite, grouping of metabolites or ratio of metabolites can indicate a response to biological stress or a specific disease state.

"The metabolic profile in biofluids, such as blood and urine, provides a snapshot of ongoing biological processes in the human body," Raftery said.

The researchers used nuclear magnetic resonance spectroscopy, a cousin of magnetic resonance imaging to detect hydrogen or carbon atoms to provide insight into the metabolites present and the visibility of certain type of metabolites, amino acids, by chemically tagging the molecules of interest so that they were more easily visible.

"We added a chemical that reacts with the amino acids and similar metabolites and forms a tag that can be seen through nuclear magnetic resonance. The tag actually is an easily identifiable isotope, in this case a carbon atom that is heavier than the standard carbon atom. Because we can easily detect this isotope, it causes these tagged metabolites to effectively pop out against the background of all of the others, Raftery said.

The findings of the study were published in the July issue of the Proceedings of the National Academy of Sc iences.


'"/>




Related medicine news :

1. Long-Term Survival can be Predicted by a Simple Lung Test
2. Simple Therapy
3. Simple Stroke Prevention is Best
4. Few Simple Steps to Lower The Incidence Of SIDS
5. A Simple Blood Test Can Predict Gum Disease
6. A Simple Exercise Can Uncover Undiagnosed Asthma
7. Simple Exercises Might Help Vertigo
8. Simple Steps To Help Fight Asthma
9. Simple Urine Test Can Help To Monitor Disfiguring Birthmarks
10. Revolutionary Simple Pregnancy Blood Test Can Save Both Mother And Child
11. Simple Procedural Improvements Can Improve Care Of Stroke Patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... ... March 29, 2017 , ... Full Contact K9, an Atlanta-based dog ... Protect Law that assists dog owners in creating legally-enforceable pet trusts for their ... the natural next step to protect their new companion. Says Evan Dunbar, CEO of ...
(Date:3/29/2017)... ... ... Brand EXOUS Bodygear announced today a special sale price for the EX-701 Knee ... the price will be only $19.97. The EXOUS Bodygear 65cm exercise ball ... $19.97). , The special promotional prices are to help individuals get their products at ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... in Carnegie, OK, from Dr. Jamie Cameron, with or without a referral. ... to traditional orthodontic treatment. Depending on each patient’s case, treatment with the FASTBRACES ...
(Date:3/29/2017)... ... March 29, 2017 , ... Curio Wellness , ... announce the finalization of the company’s executive management team with prominent executives from both ... is Curio Wellness’ Chief Operating Officer, Ted Dumbauld , who has more than ...
(Date:3/29/2017)... (PRWEB) , ... March 29, 2017 , ... Hamlin Dental ... , is now offering laser dental treatments. Dental lasers are safe and effective options, ... expands patients’ options and can improve the overall quality of care. , Dr. Hamid ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... Research and Markets has announced the addition of the "Global ... ... aesthetic devices market to grow at a CAGR of 8.12% during ... Devices Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
(Date:3/29/2017)... , March 29, 2017 Global intravenous (IV) iron ... billion by 2021, growing at a CAGR of 5%. ... by a doctor to treat anemia or other iron deficiencies. ... in the body. However, in some cases, oral administrations are ... and intravenous (IV) iron therapy comes into the picture. ...
(Date:3/29/2017)... 29, 2017  BioSpecifics Technologies Corp. (NASDAQ: BSTC), ... develop collagenase based-therapies with a first in class ... XIAFLEX ®  in the U.S. and Xiapex ® ... corporate overview at the upcoming 16 th ... 2017 at 8:00 a.m. ET in ...
Breaking Medicine Technology: