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Shire Developed DAYTRANA – The First Medication to Treat ADHD Symptom

DAYTRANA (methylphenidate transdermal system), formulated by Shire was the foremost patch medication approved to treat symptoms of ADHD in children//.

Transdermal formulation of methylphenidate - DAYTRANA, is now available in pharmacies in varying doses such as 10 mg, 15 mg, 20 mg and 30 mg. 'The availability of DAYTRANA, the first and only patch for ADHD, provides physicians and parents with a new, practical way to individualize treatment,' said Matthew Emmens, Shire Chief Executive Officer. 'DAYTRANA is a welcome new therapy for patients and Shire is pleased to offer this latest addition to our portfolio, reinforcing Shire as the market leader in ADHD.'

ADHD affects approximately 7.8 percent of all school-age children, or about 4.4 million children in the U.S. ADHD is considered the most commonly diagnosed psychiatric disorder in children and adolescents. ADHD is a neurological brain disorder that manifests as a persistent pattern of inattention and/or hyperactivity-impulsivity that is more frequent and severe than is typically observed in individuals at a comparable age and maturity. If untreated, ADHD can acutely affect a child's life, leading to problems with family members, friends, sports, after-school activities and academics.

About DAYTRANA

DAYTRANA was developed by Noven Pharmaceuticals, Inc., and combines the active ingredient, methylphenidate, with Noven's patented DOT Matrix transdermal technology. This transdermal delivery system was designed to provide continuous release of medication throughout the day. The patch is designed to stay on during the normal daily activities of a child such as swimming, exercising or bathing.

‘Since the effect of the medication in DAYTRANA starts to decrease upon patch removal, the ADHD patch allows parents, at the direction of the physician, to vary the duration of effect of the medication up to the recommended nine-hour wear time,’ said Oscar Bukstein, associate profes
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