Navigation Links
Shelved bowel-syndrome drug still in demand

After receiving thousands of letters from desperate patients, the FDA will convene a panel of outside experts to discuss whether Lotronex, an irritable bowel syndrome(IBS) medication,// can come back on the market. To meet demand, FDA official Victor Raczkowski says, his agency has expanded time allowed for public testimony at the advisory committee meeting.

IBS, affecting up to 15% of Americans, causes symptoms including lower abdominal pain, a sudden need to have a bowel movement, diarrhoea and constipation. Lotronex was the first new IBS treatment in years and the only one approved for women who mainly have diarrhoea, roughly one-sixth of all IBS patients. Glaxo Wellcome, now GlaxoSmithKline, pulled Lotronex in December 2000, 8 1/2 months after the drug's debut. About 300,000 patients had taken it, according to Glaxo.

In June 2000, the FDA began receiving reports of Lotronex users suffering severe constipation and ischemic colitis, or inflammation of the large bowel, caused by reduced blood flow. By year's end, the FDA had learned of 141 such cases, including 7 deaths, according to the Public Citizen Health Research Group, which had petitioned the agency in September 2000 to withdraw the drug. Glaxo and FDA officials have been meeting regularly since January 2001 to discuss ways of limiting adverse effects.
'"/>




Page: 1

Related medicine news :

1. Women with borderline ovarian tumors can still preserve their fertility
2. Drugs Banned worldwide still available in India
3. Antidepressants still being prescribed to Teenagers despite being banned!
4. Tinnitus: a problem which is still ambiguous
5. Anti-depressants may cause stillbirth
6. Chernobyl Disaster still Causing Cancer
7. Free Access to Taxotere Instills New Hope among Early Stage Breast Cancer Patients
8. Post-tsunami trauma still haunts children
9. Wet Distillers Grains Could Play a Role in Cattle Diets
10. "Make AIDS Therapy affordable" - Physicians demand
11. SARS: Indias drugs in demand
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... (PRWEB) , ... April 30, 2016 , ... ... engineer of patented products, announces the Pick Up Springboard, an automotive invention that ... Light Truck Manufacturing industry is worth $162 billion," says Scott Cooper, CEO and ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... Awakening , announces the addition Onnit brand Alpha BRAIN and New Mood Daily-Stress ... Onnit brain and mood optimization products to the store is just one more ...
(Date:4/29/2016)... VA (PRWEB) , ... April 29, 2016 , ... ... with student loans more flexibility in repaying their loans, more information about their ... a time when total outstanding student loan debt, including federal and private loans, ...
(Date:4/29/2016)... Philadelphia, PA (PRWEB) , ... April 29, 2016 ... ... Pennsylvania announced that student team BioCellection won the $30,000 Perlman Grand Prize of ... Impact Prize, the Gloeckner Undergraduate Award, the Michelson People‚Äôs Choice Award, and the ...
(Date:4/29/2016)... , ... April 29, 2016 , ... Dr. Robert Mondavi, ... treatments to improve smiles. Cosmetic dentistry is a fast-growing field as more patients are ... allows patients to learn more about the options currently available to them and which ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... TapImmune,Inc. (TPIV), a clinical-stage immune-oncology company ... and vaccines for the treatment of cancer & metastatic disease, ... Growth Capital Expo to be held on May 3 ... in Las Vegas, Nevada.  The Company presentation will be ... by Dr. John N. Bonfiglio a TapImmune Board ...
(Date:4/27/2016)... 27, 2016   ... in Recurring Consumable Sales  Clinical sales grow ... Technologies (Euronext: MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the ... for the first quarter ended March 31, 2016 and ... of its commercial strategy. First Quarter 2016 ...
(Date:4/27/2016)... April 27, 2016  Bayer Animal Health today ... from the University of Florida College of Veterinary ... Excellence in Communication Award (BECA). Brittany was selected ... awarded a total of $70,000 in scholarship funds ... years, Bayer has provided a total of $232,500 ...
Breaking Medicine Technology: