Navigation Links
Shelved bowel-syndrome drug still in demand

After receiving thousands of letters from desperate patients, the FDA will convene a panel of outside experts to discuss whether Lotronex, an irritable bowel syndrome(IBS) medication,// can come back on the market. To meet demand, FDA official Victor Raczkowski says, his agency has expanded time allowed for public testimony at the advisory committee meeting.

IBS, affecting up to 15% of Americans, causes symptoms including lower abdominal pain, a sudden need to have a bowel movement, diarrhoea and constipation. Lotronex was the first new IBS treatment in years and the only one approved for women who mainly have diarrhoea, roughly one-sixth of all IBS patients. Glaxo Wellcome, now GlaxoSmithKline, pulled Lotronex in December 2000, 8 1/2 months after the drug's debut. About 300,000 patients had taken it, according to Glaxo.

In June 2000, the FDA began receiving reports of Lotronex users suffering severe constipation and ischemic colitis, or inflammation of the large bowel, caused by reduced blood flow. By year's end, the FDA had learned of 141 such cases, including 7 deaths, according to the Public Citizen Health Research Group, which had petitioned the agency in September 2000 to withdraw the drug. Glaxo and FDA officials have been meeting regularly since January 2001 to discuss ways of limiting adverse effects.
'"/>




Page: 1

Related medicine news :

1. Women with borderline ovarian tumors can still preserve their fertility
2. Drugs Banned worldwide still available in India
3. Antidepressants still being prescribed to Teenagers despite being banned!
4. Tinnitus: a problem which is still ambiguous
5. Anti-depressants may cause stillbirth
6. Chernobyl Disaster still Causing Cancer
7. Free Access to Taxotere Instills New Hope among Early Stage Breast Cancer Patients
8. Post-tsunami trauma still haunts children
9. Wet Distillers Grains Could Play a Role in Cattle Diets
10. "Make AIDS Therapy affordable" - Physicians demand
11. SARS: Indias drugs in demand
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2016)... ... , ... “Epilepsy Awareness,” which can be found at the ... about epilepsy, bearing down on the social stigma and lack of public education ... within their lifetime. With such a large percentage of people affected, it’s critically ...
(Date:12/5/2016)... ... December 05, 2016 , ... Physicians Education Resource®, LLC (PER®) ... on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma, on February 24, 2017. ... to have Amy E. Herman present at this year’s conference, her unprecedented knowledge ...
(Date:12/5/2016)... (PRWEB) , ... December 05, 2016 , ... ... gender, and geographic lines. The goal of Castlewood Treatment Centers has always been ... accessible to as many people as possible. In that spirit, Castlewood has ...
(Date:12/5/2016)... ... December 05, 2016 , ... Dr. Barry M. Weintraub, one of New York ... participated in the 36th Annual Cutting Edge Aesthetic Symposium at the Waldorf Astoria in ... that perfect, yet natural-looking, nose. Dr. Weintraub, who is world-renowned for his expertise in ...
(Date:12/5/2016)... ... 2016 , ... Sideline Products is a Southern York County Pennsylvania-based premier designer ... and the horse. Smaller saddles can pinch and irritate the horse creating safety issues ... properly fitted western saddle so it does not impact the comfort or performance of ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... BOCA RATON, Fla. , Dec. 5, ... Commercialization of Public Research (the Florida Institute) ... agreement SegAna, LLC, an Orlando ... Central Florida. The Florida Institute supports new company ... funding gaps for companies spinning out of Florida-based universities ...
(Date:12/5/2016)... Dec. 5, 2016  Breckenridge Pharmaceutical, Inc. announced ... marketing agreement with development and manufacturing partner Gland ... the terms of this agreement, Breckenridge will market ... the United States . The ... ANDA. The products cover a wide range of ...
(Date:12/5/2016)... 2016  Sharn Anesthesia Inc. announced today that it ... partner for Salter Labs.  The company also received the ... of outstanding sales performance. Salter Labs is ... care, including the market gold standard ECO 2 ... of the Parker Flex-Tip® Endotracheal Tube, which is a ...
Breaking Medicine Technology: