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Sex Determination Gene Blamed For High Incidence Of Parkinson’s In Me

problems in animals were manifested in animals with low SRY level in the substantia nigra of animal brain.

'We were surprised to find a function for SRY outside the testes. The SRY gene may also explain the sex differences in other dopamine-linked disorders with a higher incidence in males, such as schizophrenia or addiction,' remarked the researchers.

Following this finding, the researchers hypothesize that men with low SRY levels could face an increased risk of developing Parkinson's disease. Furthermore, genetic variations in the SRY gene could confer an increased or decreased susceptibility to the disease. With improved understanding of such genetic mechanisms, it might be possible to identify at-risk individuals at an early stage.


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