Navigation Links
Severe Mental Retardation Gene Mutation Identified

Researchers have identified a novel gene mutation that causes X-linked mental retardation for which there was no previously known molecular diagnosis,// according to a study.

Investigators F. Lucy Raymond, University of Cambridge and Patrick S. Tarpey Wellcome Trust Sanger Institute, UK describe the ZDHHC9 gene found in those with severe retardation as being mutated to the point of entirely losing function.

"ZDHHC9 is a novel gene," explains Dr. Raymond. "This gene would not have been predicted to play a role in mental retardation based on the previous genetics work. It was found only because we were systematically looking at all the genes on the X chromosome irrespective of what they do."

X-linked mental retardation is severe. Some patients require total care and may not have language ability. The condition runs in families and only affects the male offspring. So far only a few of these genes have been identified.

Working through a large, international collaboration, the researchers collected genetic samples from 250 families in which at least two boys have mental retardation to help identify novel genes that cause X-linked mental retardation. The investigators systematically analyzed the X chromosome for gene mutations.

Dr. Raymond says that the families are receiving information from the study and using it to make decisions in their lives. "We cannot currently make their children better, but knowing that we found a genetic abnormality gives them an explanation for what has happened," she explains. "We had one family that said this knowledge was the best news they had ever been given."

"We have identified the cause of problems in certain families and are able to tell whether or not women are carriers of the condition," Dr. Raymond comments. "Consequently, the families that had previously chosen to forego having children because there was no method of testing can now be tested. We have
'"/>




Page: 1 2

Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Severe stress weakens immunity
3. Severe Acute respiratory Syndrome (SARS)
4. WHO Travel Advice to prevent spread of "Severe Acute Respiratory Syndrome (SARS)
5. Patients With Severe Hemophilia At Risk Of Developing Osteoporosis
6. Severe sleep apnea can cause liver problems
7. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
8. Strong Magnetic Stimulation Can Help Treating Severe Depression
9. Patients Suffering From Severe Mental Diseases Are At Risk Of Being Crime Victims
10. Acute Toxicity Of Nano-Scale Zinc Powder: Severe Renal Damage And Anemia
11. Poor Glycaemic Control In Hispanics With Diabetes Causes Severe Depression
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Severe Mental Retardation Gene Mutation Identified

(Date:12/21/2014)... (PRWEB) December 22, 2014 Weddingshe.com, an ... occasion gowns, has recently released its new selection of ... models are made according to the newest fashion trends. ... stunning dresses for cocktail parties . All of ... 80 percent off. We are making every effort to ...
(Date:12/21/2014)... December 21, 2014 Khanna Vision Institute ... guest at the Aspen Helicopters holiday event for underprivileged ... Santa with sleigh, flown by an aspen helicopter pilot. ... only Santa with sleigh was visible.(please see accompanying video). ... night. Dr.Khanna has helped many pilots with Pi in ...
(Date:12/21/2014)... AngelWeddingDress.com’s new collection of 2015 spring wedding dresses ... new designs in this collection, and all of them ... AngelWeddingDress.com promises to provide the most fashionable designs ... many fashion trends come and go. If ladies have ... AngelWeddingDress.com is ready to assist. , “These new ...
(Date:12/21/2014)... Dennis Thompson HealthDay Reporter ... smokers find e-cigarettes less addictive than traditional cigarettes, new research ... as they did regular cigarettes, thousands of ex-smokers said they ... and irritable over their need to smoke, researchers reported. ... was significantly less for e-cig use than for tobacco use," ...
(Date:12/21/2014)... 2014 The number of Mirena lawsuits ... litigation underway in New Jersey, Bernstein Liebhard LLP reports. ... claims involving the birth control IUD have now been ... filed by women who allege spontaneous migration of the ... perforations and other complications they were inadequately warned about ...
Breaking Medicine News(10 mins):Health News:Stunning Cocktail Party Dresses from Weddingshe.com 2Health News:2015 Spring Wedding Dresses From AngelWeddingDress Just Released 2Health News:E-Cigarettes Less Addictive Than Regular Cigarettes, Study Finds 2Health News:E-Cigarettes Less Addictive Than Regular Cigarettes, Study Finds 3Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3
... International Diabetes Federation (IDF) BRIDGES translational research grant ... seeks to reduce the risk of for people ... The community based diabetes prevention programme will determine ... research studies of lifestyle interventions for diabetes prevention ...
... YORK (May 29, 2008) -- Physician-scientists from NewYork-Presbyterian ... research findings at the American Society of Clinical ... June 3. Among the most significant presentations are ... OncoVEXGM-CSF for Patients With Unresectable Metastatic Melanoma , ...
... N.J., May 30 Lutronic, Inc., one of,the ... systems,announced today that its MOSAIC eCO2 system, the ... with the deep,ablative features of a CO2 laser, ... and,clearance., With intuitive touch-screen software, the powerful ...
... The world was stunned by the,news of ... 70,000 dead and,thousands more injured and homeless. In ... Wheelchair Mission (FWM), a non-profit,organization dedicated to transforming ... with Holistic Integrated Service Foundation (HIS),a nonprofit in ...
... Find New Video ,Milestones in Oncology, Presentations at ... The Society for Translational Oncology,(STO) is pleased to ... uniquely valuable video presentations for practicing,oncologists., (Logo: ... made on the occasion of the 2008 Annual ...
... with advanced cancer were more likely than whites to ... greater preference among blacks for life-extending treatment even in ... study led by researchers at Dana-Farber Cancer Institute in ... the annual meeting of the American Society of Clinical ...
Cached Medicine News:Health News:International Diabetes Federation grant supports study to prevent type 2 diabetes in India 2Health News:NYP/Columbia physician-scientists present at ASCO 44th annual meeting 2Health News:NYP/Columbia physician-scientists present at ASCO 44th annual meeting 3Health News:NYP/Columbia physician-scientists present at ASCO 44th annual meeting 4Health News:Soon to Be Released: Lutronic Announces the MOSAIC eCO2, the World's First 'Smart' Fractional CO2 Laser System for Treating Aesthetic and Dermatological Conditions, Will Soon Be Coming to the U.S. Market for Commercial Use 2Health News:Soon to Be Released: Lutronic Announces the MOSAIC eCO2, the World's First 'Smart' Fractional CO2 Laser System for Treating Aesthetic and Dermatological Conditions, Will Soon Be Coming to the U.S. Market for Commercial Use 3Health News:Free Wheelchair Mission to Distribute 4,400 Wheelchairs to China Earthquake Victims 2Health News:Society for Translational Oncology Launches Updated Website 2Health News:Black patients with terminal cancer more likely to choose aggressive care at end of life 2
(Date:12/19/2014)... December 18, 2014 Radiology ... that is used to store, manipulate, and distribute ... a patient tracking and scheduling system, result reporting, ... RIS with HIS and other databases improves the ... and patient scheduling, patient list management, radiology department ...
(Date:12/19/2014)... Dec. 18, 2014 Capnia, Inc. (NASDAQ: ... of medical diagnostics based on its proprietary Sensalyze™ ... today announced financial results for the third quarter ... "Following the completion of our initial public ... maximize the recently initiated CoSense® commercial launch," said ...
(Date:12/19/2014)... LYON, France , Dec. 19, 2014 /PRNewswire/ ... and Adocia (Euronext Paris: FR0011184241 – ADOC) today announced ... insulin, known as BioChaperone Lispro, for treatment in people ... relies on Adocia,s proprietary BioChaperone® technology and is currently ... will develop BioChaperone Lispro with the goal of optimizing ...
Breaking Medicine Technology:The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3
... UL, a world leader in ... device testing GmbH (MDT) and md registration support Ltd. (MDRS). ... of UL,s Life and Health business unit.   ... for the medical services industry.  MDT specializes in clinical and ...
... BETHESDA, Md., Aug. 2, 2011 /PRNewswire-Asia/ -- Chindex ... American health care company providing health care services in ... network of private primary care hospitals and affiliated ambulatory ... financial results for the second quarter and first half ...
Cached Medicine Technology:UL Expands Presence in Medical Device Market With Acquisition of MDT 2UL Expands Presence in Medical Device Market With Acquisition of MDT 3Chindex International, Inc. to Report Financial Results for the Second Quarter and First Half of 2011 2
4 Gently Curved, Prongs, 5mm Extended, Stainless Steel Tip; with Titanium Handle....
12mm from bend to 0.12mm 1x2 teeth; In Titanium....
Straight Shafts with 0.2mm 1X2 Teeth, 5mm Tying Platform; In Titanium....
Curved Shaft with 5mm Platform; 1x2, 0.12 mm teeth; In Titanium....
Medicine Products: