Navigation Links
Sertraline Can Prevent Recurrent Depressive Episodes In Diabetics

A study published in the Archives of General Psychiatry has now revealed that the risk of recurrent depression in diabetics may be effectively prevented by the antidepressant medication, Sertraline. //In addition to reducing the frequency of depressive episodes, the drug has also been found to increase the time interval between episodes of depression in diabetics.

It is believed that one in 4 diabetics end up with a diagnosis of clinical depression, leading to a substantial reduction in the quality of life and functional ability. In addition, it can increase the risk of high blood sugar level, diabetic complications and even death.

Conventional treatment with psychotherapy and anti-depressant medication has been found to be effective. However, this is only useful in short term. Furthermore, previous studies have shown that 1 in 7 diabetic patients developed resistance to the commonly used anti-depressant medication owing to incidence of recurrent depression, placing them at an increased risk for abnormally high blood sugar levels.

The researchers included 152 diabetics, all of whom had recovered from their first bout of depression following treatment with sertraline. The study participants were followed for a minimum of one year or till such time their depression recurred. During the same time, they were randomly assigned into two groups; with the experimental group receiving sertraline while the control group received a placebo instead.

Following detection of depression associated symptoms; the patients underwent a psychiatric interview. The patients’ hemoglobin levels, more specifically Hb A1c, an indicator of the blood glucose control level over the past two or three months was measured every two months.

At the end of the study, patients taking sertraline had a reduced risk of developing recurrent depression when compared to their counterparts. At the end of one year, 65.8% of the patients taking sert raline remained in remission from their depression, compared with 47.9% of those in the control group. The time interval between recurrent episodes of depression was found to be 226 days and 57 days in the sertraline and the control group respectively.

‘Using data available at the one-year point, the number needed to be treated was six patients, i.e., it would be necessary to treat six patients to spare one patient from depression recurrence,’ the authors write. All participants’ Hb A1c levels had decreased when they recovered from depression and remained lower as long as they remained depression-free, with no difference between the two study groups. Depression is increasingly understood as a recurrent and debilitating disease, especially for those with diabetes, the authors write. Physicians suspect that the more time an individual spends depressed, the greater the risk for diabetic complications and death. ‘Our study establishes a clear benefit of sertraline for prevention of depression recurrence in patients with diabetes,’ remarked the study authors.

‘Sertraline lengthened the depression-free interval of maintenance and did not interfere with glycemic improvement achieved during the recovery phase. Treatment with sertraline is relatively simple, safe and widely available, and although it is not curative, it offers patients with diabetes a potentially viable method for ameliorating the suffering, incapacity and burden associated with recurrent depression,’ concluded the researchers.

'"/>




Related medicine news :

1. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
2. Prevention is better than cure
3. Prevention of cataracts
4. Medications to Prevent Relapse to Cocaine Use
5. Estrogen Does Not Prevent Recurrent Strokes
6. Over-The-Counter Drugs May Prevent Alzheimers
7. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
8. Alcoholism Drug Fails To Prevent Drinking Relapses
9. Preventing mental decline in the aged
10. Preventing white coat hypertension
11. Simple Stroke Prevention is Best
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. ... from injury. Recently, he has implemented orthobiologic procedures as a method for treating ... one of the first doctors to perform the treatment. Orthobiologics are substances that ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys ... peers for this recognition are considered among the top 2 percent of lawyers practicing ... members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, 2016 ... Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, the ... announced today online at www.diabetesscholars.org by the ... diabetes stand in the way of academic and community ... Foundation,s scholarship program since 2012, and continues to advocate ...
(Date:6/23/2016)... June 23, 2016  Guerbet announced today that it ... Supplier Horizon Award . One of 12 ... recognized for its support of Premier members through exceptional ... excellence, and commitment to lower costs. ... recognition of our outstanding customer service from Premier," says ...
Breaking Medicine Technology: