Navigation Links
Selenium Supplements May Suppress HIV Viral Load

An article in the January 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals, shows that taking daily selenium supplements appears to increase// the level of the essential mineral in the blood and may suppress the progression of viral load in patients with HIV infection.

Advances in antiretroviral therapy (ART) have given HIV patients a longer life expectancy, however, strict adherence to the therapy is required to keep HIV viral counts low, and there is a risk of toxic effects and metabolic dysfunction. "Thus, complete control of HIV over time using ART is unlikely, and pharmacotherapeutic limitations leave a significant void in the treatment arsenal" - the authors write.

Selenium deficiencies have been observed in patients with HIV spectrum disease and evidence suggests that selenium supplements can improve immune functioning.

Barry E. Hurwitz, Ph.D., University of Miami, and colleagues conducted a double-blind, randomized, placebo-controlled trial of selenium supplements in 262 patients with HIV. Pretreatment assessment included pregnancy screening, blood tests to measure selenium levels, CD4 count (a measure of the state of the immune system; the lower the CD4 count, the more likely a patient with HIV/AIDS is to develop secondary infections or illnesses), HIV viral load (the number of copies of the HIV virus in the blood) and screening for hepatitis C.

Participants were then randomly assigned to treatment groups; 141 took a capsule containing 200 micrograms of high-selenium yeast and 121 took a similar capsule containing inactive yeast and a filler material. After nine and 18 months, physical examinations and measures of the study outcomes--HIV viral load and CD4 count--were performed.

Of the 262 patients for whom treatment was initiated, 174 (91 in the selenium group and 83 in the placebo group) completed the nine-month study assessment. "The intervention resulted in no adv erse events related to the study supplement," the authors write. The two groups had similar selenium levels at the beginning of the study, but after nine months of treatment, the average change in blood selenium level was greater in the treatment group. Higher blood selenium levels predicted a decreased HIV viral load, which in turn predicted increased CD4 count.

"The exact mechanism by which selenium exerts its effects on HIV-1 viral replication is not known, although the literature suggests several possibilities," the authors write. One hypothesis holds that selenium's antioxidant properties may repair damage done to immune cells by oxygen, which is produced at higher levels in the bodies of patients with HIV. However, future research is needed to confirm this relationship.

"Given the challenges of using conventional pharmacotherapy to achieve and maintain virologic suppression in HIV-spectrum disease, our results support the use of selenium as a simple, inexpensive and safe adjunct therapy," the authors conclude.

Source-Eurekalert
SRI
'"/>




Related medicine news :

1. Selenium linked to osteoarthritis
2. Antioxidant Selenium Offers No Major Protection against Heart-Disease
3. Selenium Supplements May Slow Progression of HIV: Report
4. Higher Serum Selenium Linked With Reduced Risks of Prostate Cancer - in Some Men
5. Mislabeled Body-building Steroid Supplements
6. Garlic Supplements Impede HIV Therapy
7. Lactobacillus Supplements shorten the duration of diarrhoea
8. Supplements for Ear Infections
9. Benefits of Vitamin Supplements Unclear
10. Vitamin- B Supplements Beneficial in Depression Treatment
11. Weight Loss Supplements Questioned
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , ... mock evacuation of the facility as part of a disaster drill on October 3rd. ... EMS and Shelton City Emergency Manager, as well as the Connecticut Long Term ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released ... understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture ... Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that is ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... for healthcare compliance program management, will showcase a range of technology and learning ... Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 at ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of ... Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, ... In honor of Morris F. Collen, a pioneer in the field of medical informatics, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s National ... 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. ... for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, Inc. ... earnings conference call and webcast on Friday, November 3, ... (EDT) and ending at approximately 8:30 a.m. (CDT) / ... the company,s 2017 financial performance and guidance for 2018, ... initiatives to enhance operational performance, and long-range financial outlook ...
Breaking Medicine Technology: