Navigation Links
Scientists reveal mechanism behind high-fat, diabetes link.

As a ray of hope, comes the research that links high fat diet to Type 2 Diabetes and so can suggest ways to avoid it.

Cell journal featured the study which identifies a molecular link between the // consumption of fatty foods and the disruption of insulin production.

University of California, San Diego (UCSD) School of Medicine, scientist say that a single gene encoding the enzyme GnT-4a glycosyltransferase (GnT-4a) is key to enabling the beta cells in the pancreas to sense blood glucose levels and appropriately produce insulin. This enzyme is not able to act by a high-fat diet, resulting in pancreatic beta cell failure and eventually leading to type 2 diabetes.

Done in mice they found that mice lacking the GnT-4a gene had elevated blood glucose concentrations, indicating diabetes. The consequent failure of beta cells to normally secrete insulin resulted in the development of the disease.

According to the latest research, the key role of the GnT-4a enzyme is to maintain glucose transporters on the surface of the beta cells in the pancreas. Pancreatic glucose transporters are necessary at the beta cell surface to sense glucose levels in the blood.

Dr Jamey Marth, UCSD professor of cellular and molecular medicine said, “Our findings suggest that the current human epidemic in type 2 diabetes may be a result of GnT-4a enzyme deficiency. The GnT-4a enzyme is required to synthesize a glycan structure that holds the glucose transporter in place at the beta cell surface. The loss of this key transporter is directly linked to reduced GnT-4a protein glycosylation, a high-fat diet, and type 2 diabetes.”

According to Marth and his colleagues, their latest findings could lead to a new approach to the prevention of diabetes resulting from a high-fat diet. This could be a big step in preventing this lifestyle disease.


'"/>




Page: 1

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists reveal mechanism behind high fat diabetes link

(Date:9/23/2014)... York, NY (PRWEB) September 23, 2014 ... a moderate rate over the past five years. Growth ... health consciousness has encouraged Canadians to consume more fish ... has encouraged food retailers and food-service establishments to increase ... increasing industry revenue. Additionally, strong economic growth in much ...
(Date:9/23/2014)... 2014 Oaksterdam University has begun publishing ... its first post, the University addresses the need for ... industry. , The cannabis industry is becoming big business. ... an 18-month boost of more than $600 million in ... sales. And, the new legal recreational marijuana market in ...
(Date:9/23/2014)... "The primary purpose of the CALL LIGHT ... from Sacramento, Ca.. "Call lights are often found on the ... the IV pole out of the patient's reach. In order ... whenever they need it, I created this caddy." , She ... call device within easy reach. The accessory ensures that the ...
(Date:9/23/2014)... California, Davis, and Academia Sinica, the preeminent academic ... entered into a collaborative agreement to develop a ... cutting-edge research with opportunities to translate innovative technologies ... The agreement was signed Sept.12 in Taipei by ... Davis and President Chi-Huey Wong of Academia Sinica. ...
(Date:9/23/2014)... September 23, 2014 AttorneyOne.com, a recognized ... the latest information from the FDA on Jalapeno ... that its Private Label Jalapeno Bagels are recalled as ... Publix Jalapeno Bagels were sold in the ... , Taking into consideration the latest developments, AttorneyOne.com ...
Breaking Medicine News(10 mins):Health News:Fish and Seafood Wholesaling in Canada Industry Market Research Report Now Available from IBISWorld 2Health News:Fish and Seafood Wholesaling in Canada Industry Market Research Report Now Available from IBISWorld 3Health News:Oaksterdam University Addresses "Why Quality Training Matters in a Growing Marijuana Industry" in First Blog Post 2Health News:Oaksterdam University Addresses "Why Quality Training Matters in a Growing Marijuana Industry" in First Blog Post 3Health News:Academia Sinica, UC Davis sign agreement on exchanges and tech transfer 2Health News:Publix Private Label Jalapeno Bagels Recalled: AttorneyOne Monitors and Keeps Consumers Informed 2
... CellCyte Genetics Corporation (CellCyte) (OTC Bulletin Board: ... published by the Seattle Times reporting ... incorrectly reported that CellCyte ,closes.,In CellCyte,s August 14, ... its bioreactor business segment and generally described its ...
... Dec. 29 Watson Pharmaceuticals,Inc. (NYSE: ... branded pharmaceuticals,today announced that its subsidiary, Watson Laboratories, ... Food and Drug Administration on its,Abbreviated New Drug ... USP, 0.15 mg / 0.02 mg. Desogestrel/ethinyl,estradiol ...
... Priority ReviewEAST BRUNSWICK, N.J., Dec. 29 Savient ... announced that the U.S. Food and Drug Administration ... License Application (BLA) for pegloticase, a novel biological ... also granted the Company,s BLA with a priority ...
... Cross and Blue Shield of Oklahoma announced today the ... their next policy year. This change will not in ... always been available to children with autism. Blue Cross ... interests in the benefits and coverage of certain autism-related ...
... Dec. 29 Eastern Life & Health Insurance Company (ELH), ... EIHI ), announced today that it will add vision to ... include a vision insurance plan and a vision discount program, ... "Adding vision to ELH,s product portfolio enables employers to offer ...
... 29 Life for Relief and Development (LIFE), a ... the civilian victims of the recent conflict in Gaza. ... non-governmental organizations operating in the area, LIFE has obtained ... relief items to Gaza via a specially designated humanitarian ...
Cached Medicine News:Health News:CellCyte Genetics Corporation: Seattle Times Erroneously Reports That CellCyte 'Closes' 2Health News:CellCyte Genetics Corporation: Seattle Times Erroneously Reports That CellCyte 'Closes' 3Health News:CellCyte Genetics Corporation: Seattle Times Erroneously Reports That CellCyte 'Closes' 4Health News:CellCyte Genetics Corporation: Seattle Times Erroneously Reports That CellCyte 'Closes' 5Health News:Watson Pharmaceuticals Receives FDA Final Approval for Generic Mircette(R) 2Health News:Pegloticase BLA Filing Accepted for Priority Review by FDA 2Health News:Pegloticase BLA Filing Accepted for Priority Review by FDA 3Health News:Pegloticase BLA Filing Accepted for Priority Review by FDA 4Health News:Blue Cross and Blue Shield of Oklahoma Announces Autism Benefits 2Health News:Eastern Life & Health Introduces New Vision Product 2Health News:Eastern Life & Health Introduces New Vision Product 3
(Date:9/23/2014)... September 23, 2014 ... lors d,une série de démonstrations personnelles   ... le domaine de l,analyse de la dysmorphologie ... stand n° 1035 lors de la réunion ASHG 2014, ... Diego , en Californie. FDNA présentera ...
(Date:9/23/2014)... 2014 Dans les ... le ferroviaire ou encore l,énergie, les machines, ... accès à leurs données. Ces données de ... au cœur des voitures, trains, avions, appareils ... milliards le nombre de machines connectées d,ici ...
(Date:9/23/2014)... and DUBLIN , Sept. ... ("we" or the "Company"), a biotechnology company pioneering ... autoimmune diseases in emerging nations, today announced that ... common stock for DTC,s Deposit and Withdrawal at ... Transfer Service ("FAST") transfer agent as the distribution ...
Breaking Medicine Technology:FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 2FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 3Altran transforme le big data du monde industriel en nouveau business 2TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 2TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 3TNI BioTech, Inc. Announces Its Stock is Now DTC DWAC/FAST Eligible 4
... Sept. 22, 2011 Prime Therapeutics (Prime), a leading ... program called CareCentered Contracting™, aimed at ensuring Prime members ... health. Through CareCentered Contracting, pharmaceutical companies ... for patients whose medication does not work as expected, ...
... Sept. 22, 2011 Shire plc (LSE: SHP, NASDAQ: ... announces an update on the approval status and availability ... treatment of symptomatic orthostatic hypotension (SOH).  Shire has engaged ... Administration (FDA) for the past 12 months in the ...
Cached Medicine Technology:Prime Therapeutics Launches CareCentered Contracting™ Program 2Shire Provides Update on ProAmatine® (midodrine HCl) 2Shire Provides Update on ProAmatine® (midodrine HCl) 3Shire Provides Update on ProAmatine® (midodrine HCl) 4
... workmanship are the hallmark of these stereozoom ... mind. The top (incident) circular 9W fluorescent ... while remaining cool to the touch. Binocular ... 10x to 44x zoom magnification or high-power ...
... system expandability: the first inverted microscope to ... infinity space. Multi-port design enables optical input/output ... variety of illumination and detector equipment. Extendable ... an optional light source and other attachments ...
... Megapixel color imaging camera system designed ... high performance, megapixel digital cameras provides ... view them on a PC via ... This "live" previewing capability is accompanied ...
... camera with direct digital output. Three-chip color ... Olympus wide array of high-quality color video ... and flexibility you need for an efficient ... high-resolution, real-time image of your specimen that ...
Medicine Products: